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囊纤维化
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  “囊纤维化”译为未确定词的双语例句
     The positive PCNA expression in the equatorial part was greater than that in subcapsular part of anterior capsule at many time stages within the first month after operation (P<0.01).
     术后 2个月后囊纤维化。 ③赤道部PCNA阳性表达强于前囊下部 ,术后 1天、 3天、 1个月与前囊下相比P <0 0 1,术后 1周、 2~ 5个月P >0 0 5。
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  相似匹配句对
     Cystic Fibrosis
     纤维化
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     CFTR and cystic fibrosis
     CFTR与纤维化
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     Pancreatic fibrosis
     胰腺纤维化
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     interstitial fibrosis.
     间质纤维化
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     fimbriatum Hook., D.
     、唇石斛D.
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  cystic fibrosis
The Mutation Spectrum of the CFTR Gene in Cystic Fibrosis Patients from Bashkortostan
      
Mutations of CFTR were studied in patients with cystic fibrosis (CF) from Bashkortostan.
      
Polymorphisms of the Cytochrome P450 (CYP1A1, CYP2E1) and Microsomal Epoxide Hydrolase (mEPHX) Genes in Cystic Fibrosis and Chro
      
Frequencies of CYP1A1, CYP2E1, and mEPHX polymorphic variants were analyzed in cystic fibrosis, chronic obstructive lung disease, bronchiectatic disease, chronic nonobstructive bronchitis, and recurring bronchitis.
      
Mutations in CYP1A1 and mEPHX were shown to modify the severity of respiratory disorders in cystic fibrosis, the combination of CYP1A1 genotype Val/Val with the "very slow" mEPHX phenotype being most unfavorable (odds ratio OR = 12.30).
      
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Objective To study the effect of alginate purity on microencapsule overgrowth, histology and function of microencapsulated hepatocyte (MH). Methods Alginate was purified by filtration and chloroform/butanol extraction. Using purified and crude alginate to make two kinds of MHs, we transplanted each kind of MHs into the peritoneal cavities of rats. After 2 weeks, 1, 2 and 6 months, MHs were washed out to study overgrowth of MH, histology, and expression of enzyme and albumin in hepatocytes. Two kinds of MHs...

Objective To study the effect of alginate purity on microencapsule overgrowth, histology and function of microencapsulated hepatocyte (MH). Methods Alginate was purified by filtration and chloroform/butanol extraction. Using purified and crude alginate to make two kinds of MHs, we transplanted each kind of MHs into the peritoneal cavities of rats. After 2 weeks, 1, 2 and 6 months, MHs were washed out to study overgrowth of MH, histology, and expression of enzyme and albumin in hepatocytes. Two kinds of MHs (the purified and the crude) were transplanted to FHF rats separately to study their differences in liver function support. Results The amount of retrieved MHs was larger in the purified than in the crude ( P <0.001). In the purified group, most hepatocytes had normal morphology, positive enzymatic histochemistry and albumin immuno histochemistry stain in one month of transplantation but were damaged in the crude group only 2 weeks later. Microencapsules were smooth and no overgrowth was observed during 6 months in the purified but all overgrowth one month later after transplantation in the crude. The purified MHs had excellent liver function support in the FHF comparing with the crude and the control. Conclusion The purified alginate may significantly reduce the overgrowth of MHs and improve the function of hepatocytes.

目的研究海藻酸钠纯度对微囊纤维化及囊内肝细胞组织形态、功能的影响。方法采用逐步过滤和氯仿和丁醇萃取蛋白的方法纯化海藻酸钠,用纯化和未纯化的海藻酸钠制作两种微囊化肝细胞,分别作同种异体腹腔移植并观察移植后不同时期(2周、1、2、和6个月)微囊和囊内肝细胞的组织结构、功能表达及对急性肝衰大鼠存活率的影响。结果纯化组的微囊回收率较未纯化组明显增高(P<0.001)。纯化组移植1个月时大部分肝细胞组织形态、酶和白蛋白染色与正常肝细胞差异不显著,未纯化组移植1个月内肝细胞破坏。长期移植(2、6个月),纯化组微囊仍保持完整光滑,但肝细胞破坏;纯化组的微囊化肝细胞治疗急性肝衰较未纯化组效果明显。结论纯化海藻酸钠能降低微囊的纤维化程度,改善囊内肝细胞功能。

To evaluate the long-term and short-term efficacy of the plant with valve rubber tuber implantation for refractory glaucoma and discuss its intraoperative and postoperative complication and management. Methods 50 cases of refractory glaucoma under-went the plant with valve rubber implantation, including 29 cases of neovascular glaucoma, 2 cases of congenital glaucoma, 5 cases of primary angle-closure glaucoma after operation and 14 cases of secondary glaucoma. Results The total success rate of intraocular...

To evaluate the long-term and short-term efficacy of the plant with valve rubber tuber implantation for refractory glaucoma and discuss its intraoperative and postoperative complication and management. Methods 50 cases of refractory glaucoma under-went the plant with valve rubber implantation, including 29 cases of neovascular glaucoma, 2 cases of congenital glaucoma, 5 cases of primary angle-closure glaucoma after operation and 14 cases of secondary glaucoma. Results The total success rate of intraocular pressure (IOP) was 76.0%. One month postoperatively, the success rate was 82.0%. Six months postoperatiively, the success rate was 71.3%. Five years postoperatively, the success rate was 70.0%. The complications include transient hyphema, flat anterior chamber, hypotony, tube blockage, fibroid filtering bleb etc. Conclusions This therapeatic mothod is effective in management of refractory glaucoma in spite of its unnegligible complications.

目的 评价顽固性青光眼经带盘阀门导管植入术治疗的远、近期疗效 ,探讨术中、术后并发症及预防。方法 对5 0例顽固性青光眼行颞上象限前房到赤道部区域的带盘阀门导管植入术。其中新生血管性青光眼 2 9例 ,先天性青光眼 2例 ,原发性闭角型青光眼术后 5例 ,其他继发性青光眼 14例。结果 总眼压控制率为 76 0 % ,其中术后 1月为 82 0 % ,6月为71 3 % ,5年以上为 70 0 %。术后并发症包括前房出血 ,导管口堵塞 ,浅前房、低眼压 ,滤过泡包囊纤维化 ,植入盘脱出等。结论 尽管本手术存在一些不容忽视的并发症 ,但对于顽固性青光眼仍不失为有效的治疗方法。

Objectives To investigate the effects of HOE 077 on the fibrotic overgrowth around implanted microcapsules and viability of encapsulated islets. Methods Porcine islet cells were encapsulated in barium alginate capsules after isolation. The islet containing microcapsules were implanted into the liver of Balb/c mice. HOE 077 was administered with the drinking water ( 1.5 ?mg/ml), while the controls received only water. After 4 weeks, the capsules were retrieved for histological examination. The severity...

Objectives To investigate the effects of HOE 077 on the fibrotic overgrowth around implanted microcapsules and viability of encapsulated islets. Methods Porcine islet cells were encapsulated in barium alginate capsules after isolation. The islet containing microcapsules were implanted into the liver of Balb/c mice. HOE 077 was administered with the drinking water ( 1.5 ?mg/ml), while the controls received only water. After 4 weeks, the capsules were retrieved for histological examination. The severity of fibrotic reaction to the capsules and the viability of islet cells were determined. Results In the control group, encapsulated islet cells implanted into liver were surrounded with cell rich, fibrotic tissue. The mean thickness of cell infiltration was ( 62.12 ± 3.84 )μm and the viability was ( 15.16 ± 2.32 )%. In contrast, the thickness of fibrosis in the HOE 077 treated group was ( 41.44 ± 2.45 )μm and the viability was ( 23.08 ± 2.45 )%. A significant difference in mean cell infiltrating thickness and viability between the two groups was observed ( P < 0.000 1 and P < 0.01 ,respectively). Conclusions Administration of compound HOE 077 could be a novel approach for preventing fibrotic reaction to encapsulated islets and improving the graft survival.

目的 研究抗肝纤维化药物HOE 0 77对胰岛微囊外纤维化反应及细胞活力的影响。方法 猪胰岛分离后包裹在海藻酸钡微囊内 ,移植于Balb/c小鼠肝内。术后HOE 0 77通过溶解于饮用水中给药 ,对照组饮水中不含HOE 0 77。 1个月后处死动物 ,病理检查观察包囊外的纤维化反应程度 ,评价囊内细胞的存活情况。结果 对照组显示了明显的纤维化反应 ,纤维包裹层厚度平均为(6 2 .12± 3.84) μm ,细胞活力为 (15 .16± 2 .32 ) % ;而HOE 0 77治疗组纤维包裹厚度为 (4 1.44±2 .45 ) μm ,活力为 (2 3 .0 8± 2 .45 ) %。统计学分析表明 ,两组在囊外纤维包裹层的厚度及细胞活力上差异均有显著性 (P <0 .0 0 0 1和P <0 .0 1)。结论 抗肝纤维化药物HOE 0 77的应用为减轻微包囊的纤维化反应提供了一个新的途径

 
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