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冠心病风险
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  cad risk
    These datas suggest that they lend strong support for the possibility that in the near future indi-viduals will be offered special exercise prescriptions based on ApoE genotype to improve plasma lipoprotein-lipid profiles and CAD risk.
    上述结论提示我们在不久的将来,依据ApoE基因型制定个体改善血浆脂蛋白和冠心病风险的特异性运动处方将成为可能。
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  “冠心病风险”译为未确定词的双语例句
    The object of the study was to type the single nucleotide polymorphisms(SNPs) in the promoter of TNF-α at-1031、 -863、 -857、 -238 locus in Chinese han population of Hubei and investigated the correlation between TNF-α polymorphisms and CHD.
    本研究的目的是了解中国湖北地区的汉族人群中TNF-α启动子上游-1031、-863、-857、-238位点的多态性,及这些位点的多态性在冠心病患者中的分布频率,判断基因型与冠心病风险的相关性。
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    Higher TWAR IgG antibody titres(IgG≥1:16)were associated with increased risk of CHD(OR 4.36,95% CI 2.32-8.16) Conclusions:There are higher chronic Chlamydia pneumoniae infection rate and TWAR IgG GMT in CHD.
    随着肺炎衣原体IgG抗体水平(IgG≥1∶16)的增高,发生冠心病风险相对增高(OR 4.36,95%CI 2.32~8.16)。 不稳定性心绞痛病人、急性心肌梗塞病人血清肺炎衣原体IgG平均几何滴度及感染阳性率均无明显差别,但两者与正常对照组相比均有非常显著性差异(P<0.001)。
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    Conclusion The decrease in levels of T-Bil and the increase in levels of TC and AST in serum might be associated with the increased risk of the prevalence of coronary artery disease among soldiers in plateau. The association of variations of the levels of T-Bil with the levels of the D-Bil in serum was not found.
    结论T-Bil减低及TC和AST增高,可能与移居高原习服者罹患冠心病风险增加有关,T-Bil改变与D-Bil无关。
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    Association of European population of levels of thrombotic and inflammatoy factors with risk of coronary heart disease: The MONICA Optional Haemostasis Study
    欧洲人群的血栓形成及炎症因子水平与冠心病风险的关系:MONICA选择性凝血研究
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    Elevated serum alanine aminotransferase activity and calculated risk of coronary heart disease in the United States
    血清ALT活性升高与冠心病风险之间的关系
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  cad risk
The recently released Adult Treatment Panel III guidelines suggest that because elevated TGs are an independent CAD risk factor, some TG-rich lipoproteins, commonly called remnant lipoproteins, must be atherogenic.
      
These observations suggest that GST-null genotypes strengthen the effect of smoking on CAD risk by modulating the detoxification of genotoxic atherogens.
      
The increase in CAD risk was most evident among individuals with early-onset CAD (age ≤50 years), whereas in older CAD subjects other factors, and not the adiponectin SNP, were the major determinants.
      
However, it remains unclear as to whether the relative lack of coronary atherosclerosis was the direct consequence of CETP deficiency and/or the lack of traditional CAD risk factors.
      
An increase of low-density lipoprotein triglycerides (LDL-Tg) was found to be an independent coronary artery disease (CAD) risk factor for non-insulin-dependent diabetic (NIDDM) patients in a recent prospective study.
      
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Objective To explore the regularities of the variations of the levels of the total bilirubin in serum and lipid metabolism of acclimatized people Methods 140 acclimatized soldiers were divided into 4 groups,such as 1st group (0 5~1 year, n =50),2nd group (2~4 years ,n =30),3rd group(5~10 years, n =30),and 4 th group (>10 years, n =30),based on their residential durations in plateau The levels of total bilirubin(T Bil),direct bilirubin(D Bil),albumin(Ab),triglycerides(TG),total chelesterol(TC),low...

Objective To explore the regularities of the variations of the levels of the total bilirubin in serum and lipid metabolism of acclimatized people Methods 140 acclimatized soldiers were divided into 4 groups,such as 1st group (0 5~1 year, n =50),2nd group (2~4 years ,n =30),3rd group(5~10 years, n =30),and 4 th group (>10 years, n =30),based on their residential durations in plateau The levels of total bilirubin(T Bil),direct bilirubin(D Bil),albumin(Ab),triglycerides(TG),total chelesterol(TC),low density lipoprotein(LDL c),and high density lipoprotein(HDL c) in serum were determined among soldiers in 4 groups Results No significant differences were found in all observed indexes between the 1 st group and the 2nd group Significant decreases of the levels of T Bil ( P<0 001 ) and significant increases of the levels of TC ( P<0 05 ) in serum were observed in the 3rd group and the 4th group compared with those in the 1st group and 2 nd group No significant differences were observed in the levels of D Bil,Ab,LDL c,HDL c,and TG between all observed groups( P>0 05 ) Conclusion The decreases of the levels of T Bil and the increases of the levels of TC in serum might be associated with the increase of the risk of the prevalance of coronary artery disease (CAD) among acclimatized people in plateau with the residential durations of more than 5 years,in spite of no significant variations of the levels of TG,LDL c and HDL c in serum The association of variations of the levels of T Bil with the levels of D Bil and Ab in serum was not found

目的 探讨高原习服者血清总胆红素 (T- Bil)演变规律及脂代谢的变化。方法 将 140名习服者 ,按留居高原时间分为组 1(0 .5~ 1年 ,n=5 0 )、组 2 (2~ 4年 ,n=30 )、组 3(5~ 10年 ,n=30 )、组 4(>10年 ,n=30 )。检测其血清总胆红素 (T- Bil)、直接胆红素 (D- Bil)、白蛋白 (Ab)、甘油三酯 (TG)、总胆固醇 (TC)、低密度脂蛋白 (L DL- c)及高密度脂蛋白(HDL - C)。结果 组 1和组 2各指标差异无显著性。与组 1和组 2相比 ,组 3和组 4T- Bil显著下降 (P<0 .0 0 1)、总胆固醇 (TC)增高 (P<0 .0 5 ) ;血清直接胆红素 (D- Bil)、白蛋白 (Ab)、低密度脂蛋白 (L DL - c)、高密度脂蛋白 (HDL - c)及甘油三酯 (TG)在各组间差异均无显著性 (P>0 .0 5 )。结论 T- Bil减低及 TC增高 ,可能与留居高原习服者罹患冠心病风险增加有关 ,虽然其 TG、L DL- c和 HDL- c无变化 ;T- Bil改变与 D- Bil、Ab无关

Objective:To evaluate the association between chlamydia pneumoniae infection and coronary heart disease. Methods:TWAR IgG,IgM antibodies were measured by microimmuno fluorescence test on admission in 115 patients with coronary heart disease(CHD)and 60 subjects without CHD. Results:Geometric mean IgG titre(IgG GMT)was significantly higher in patients with CHD(1:57.77±4.42,p<0.001)compared with the controls(1:19.93±4.29,p<0.001).The frepuency of chronic infection was sig nificantly higher in CHD group...

Objective:To evaluate the association between chlamydia pneumoniae infection and coronary heart disease. Methods:TWAR IgG,IgM antibodies were measured by microimmuno fluorescence test on admission in 115 patients with coronary heart disease(CHD)and 60 subjects without CHD. Results:Geometric mean IgG titre(IgG GMT)was significantly higher in patients with CHD(1:57.77±4.42,p<0.001)compared with the controls(1:19.93±4.29,p<0.001).The frepuency of chronic infection was sig nificantly higher in CHD group than in the controls (70.4% vs.36.7%,p<0.001).No significant difference of acute infection(p>0.05)was found between both groups.Higher TWAR IgG antibody titres(IgG≥1:16)were associated with increased risk of CHD(OR 4.36,95% CI 2.32-8.16) Conclusions:There are higher chronic Chlamydia pneumoniae infection rate and TWAR IgG GMT in CHD.Higher TWAR IgG antibody titers are associated with increased risk of CHD.Chronic chlamydia pneumoniae infection may be a risk factor for the developing of CHD.

目的:通过测定血清肺炎衣原体(TWAR)IgG、IgM抗体滴度水平,探讨肺炎衣原体感染与冠心病的相关性。    方法:应用间接微量免疫荧光法,测定115例冠心病病人(冠心病组)和60例健康人(正常对照组)血清肺炎衣原体IgG、IgM抗体滴度。    结果:冠心病组病人血清肺炎衣原体IgG平均几何滴度(GMT)(1∶57.77±4.42)与正常对照组(1∶19.93±4.29)相比有非常显著性差异(P<0.001)。冠心病组肺炎衣原体既往感染阳性率明显高于正常对照组(70.4%vs 36.7%,P<0.001),2组急性感染阳性率无明显差异(P>0.05)。随着肺炎衣原体IgG抗体水平(IgG≥1∶16)的增高,发生冠心病风险相对增高(OR 4.36,95%CI 2.32~8.16)。不稳定性心绞痛病人、急性心肌梗塞病人血清肺炎衣原体IgG平均几何滴度及感染阳性率均无明显差别,但两者与正常对照组相比均有非常显著性差异(P<0.001)。    结论:研究结果表明,冠心病组病人肺炎衣原体感染率及血清肺炎衣原体IgG平均几何滴度均较高,有抗体者(IgG≥1∶16)发生冠心病的风险相对增加,肺炎衣原体感染...

目的:通过测定血清肺炎衣原体(TWAR)IgG、IgM抗体滴度水平,探讨肺炎衣原体感染与冠心病的相关性。    方法:应用间接微量免疫荧光法,测定115例冠心病病人(冠心病组)和60例健康人(正常对照组)血清肺炎衣原体IgG、IgM抗体滴度。    结果:冠心病组病人血清肺炎衣原体IgG平均几何滴度(GMT)(1∶57.77±4.42)与正常对照组(1∶19.93±4.29)相比有非常显著性差异(P<0.001)。冠心病组肺炎衣原体既往感染阳性率明显高于正常对照组(70.4%vs 36.7%,P<0.001),2组急性感染阳性率无明显差异(P>0.05)。随着肺炎衣原体IgG抗体水平(IgG≥1∶16)的增高,发生冠心病风险相对增高(OR 4.36,95%CI 2.32~8.16)。不稳定性心绞痛病人、急性心肌梗塞病人血清肺炎衣原体IgG平均几何滴度及感染阳性率均无明显差别,但两者与正常对照组相比均有非常显著性差异(P<0.001)。    结论:研究结果表明,冠心病组病人肺炎衣原体感染率及血清肺炎衣原体IgG平均几何滴度均较高,有抗体者(IgG≥1∶16)发生冠心病的风险相对增加,肺炎衣原体感染可能是构成?

Objective To determine the association of cigarette smoking and coronary artery diseases (CAD). Methods A case control study involving 355 people classified as CAD or without CAD was performed. But people treated with diuretic,aspirin, lipid lowering agents, heparin or those with renal, hepatic diseases were excluded. Gender, age, body mass index, plasma glucose under fasting, total cholesterol,triglyceride,high density lipoprotein cholesterol, low density lipoprotein cholesterol, fibrinogen, cigarette...

Objective To determine the association of cigarette smoking and coronary artery diseases (CAD). Methods A case control study involving 355 people classified as CAD or without CAD was performed. But people treated with diuretic,aspirin, lipid lowering agents, heparin or those with renal, hepatic diseases were excluded. Gender, age, body mass index, plasma glucose under fasting, total cholesterol,triglyceride,high density lipoprotein cholesterol, low density lipoprotein cholesterol, fibrinogen, cigarette smoking consumption grade (0:no smoking,1:less or equal 100 cigarette year,2:one hundred cigarette year< cigarette index≤200 cigarettes year,3:greater than 200 cigarette year), CAD family history, essential hypertension and CAD severity were analyzed. Results In multiple logistic regression, age, gender, fasting plasma glucose, fibrinogen and cigarette smoking showed significant independent association with CAD. Compared with non smoker, the odds ratio ( OR ) of CAD of grade 3 cigarette smoking was 3.519 (95% CI : 1.538 8.053 , P = 0.003 ). However with grade 1 cigarette smoking group, no significant independent association was found with CAD ( OR = 0.948 , P = 0.959 ). With more than grade 2 [grade 2+3, compared with less than grade 2(0+1)] and grade 3 [compared with less than grade 3 (0+1+2)] cigarette smoking, ORs of CAD were 2.094 ( P = 0.027 ), 3.463 ( P = 0.002 ) respectively.Three handred fifty five people were divided into 3 groups: control, stable angina (SA) and unstable angina (UA) groups. In multinomial logistic regression, when comparing with UA, parameter estimate of cigarette smoking degree in the SA group were β= -0.220 , s = 0.138 , P = 0.112 , OR = 0.803 respertively. Conclutions Cigarette smoking was a significant independent risk factor for CAD. With more cigarettes smoked,a higher odds ratio of CAD was seen. Gender, age,fibrinogen and plasma glucose during fasting were also independent factors significantly associated with CAD. No significant independent association between cigarette smoking and unstable angina was found.

目的 确定吸烟量与冠心病的关系。方法  35 5例行冠状动脉造影的患者 (A组 ,无冠心病患者 14 2例 ;B组 ,冠心病患者 2 13例 ) ,以性别、年龄、体重指数、空腹血糖、总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、纤维蛋白原、吸烟量等级、冠心病家族史、高血压病等多重危险因素以及冠状动脉严重程度评分进行多变量分析。结果 单因素分析 ,冠心病的OR值 95 %可信区间 (CI) :吸烟与不吸烟比较为 1.6 2 9~ 2 .5 98,P <0 .0 5 ;吸烟 3级时与不吸烟比较为 1.2 6 0~3.90 7,P <0 .0 1。多元logistic回归分析显示 :吸烟等级、性别、纤维蛋白原、空腹血糖与冠心病相关 ,年龄与冠心病基本相关。各吸烟级别分别进行多元logistic回归分析显示 :与不吸烟组比较 ,吸烟 1级时与冠心病无关 (OR =0 .94 8,P =0 .95 9) ,吸烟 3级的冠心病风险OR为 3.5 19(P =0 .0 0 3,95 %CI :1.5 38~ 8.0 5 3) ;吸烟 2级以上 (2 +3级 )与 2级以下 (0 +1)比较 ,OR...

目的 确定吸烟量与冠心病的关系。方法  35 5例行冠状动脉造影的患者 (A组 ,无冠心病患者 14 2例 ;B组 ,冠心病患者 2 13例 ) ,以性别、年龄、体重指数、空腹血糖、总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、纤维蛋白原、吸烟量等级、冠心病家族史、高血压病等多重危险因素以及冠状动脉严重程度评分进行多变量分析。结果 单因素分析 ,冠心病的OR值 95 %可信区间 (CI) :吸烟与不吸烟比较为 1.6 2 9~ 2 .5 98,P <0 .0 5 ;吸烟 3级时与不吸烟比较为 1.2 6 0~3.90 7,P <0 .0 1。多元logistic回归分析显示 :吸烟等级、性别、纤维蛋白原、空腹血糖与冠心病相关 ,年龄与冠心病基本相关。各吸烟级别分别进行多元logistic回归分析显示 :与不吸烟组比较 ,吸烟 1级时与冠心病无关 (OR =0 .94 8,P =0 .95 9) ,吸烟 3级的冠心病风险OR为 3.5 19(P =0 .0 0 3,95 %CI :1.5 38~ 8.0 5 3) ;吸烟 2级以上 (2 +3级 )与 2级以下 (0 +1)比较 ,OR为 2 .0 94 (P =0 .0 2 7) ,3级与3级以下 (0 +1+2 )比较OR为 3.4 6 3(P =0 .0 0 2 )。以上病例分为 3组 :对照组、稳定型心绞痛组和不稳定型心绞痛组。用多维logistic回归分析显示 ,与不稳定型心绞痛比较 ,稳定型心绞痛组吸烟对患不稳定型心绞痛的风险OR?

 
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