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基因p
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  gene p
     Unknown Gene P2.18
     未知基因p2.18
短句来源
     The genotypes at I462V site in exon 7 of CYP1A1 gene,GSTM1,GSTT1,I105V site in GSTP1gene,Pst1 and Dra1 sites in CYP2E1 gene,P187S site in NQO1 gene,Kpn1,BamH1 and Taq1 sites in NAT2 gene, and H113Y, R139H sites in mEH gene were determined by PCR-based methods.
     分析了CYP1A1基因第 7外显子I4 6 2V位点、GSTM1、GSTT1、GSTP1基因I10 5V位点、CYP2E1基因 5’非编码区的Pst1位点和第 6内含子的Dra1位点、NQO1基因P187S位点、NAT2基因Kpn1、BamH1和Taq1位点以及mEH基因H113Y和R139H位点的多态性 ;
短句来源
     Study on ras Gene, P~(53) Gene and Pancreas Carcinoma
     ras基因P~(53)基因与胰腺癌研究近况
短句来源
     Identification of the TNF-α Response Element in Human Acyl-coenzyme A: Cholesterol Acyltransferase-1 Gene P1 Promoter
     人酰基辅酶A:胆固醇酰基转移酶-1基因P1启动子的TNF-α效应元件分析鉴定
短句来源
     The effects of CdSO 4 on human lung cancer susceptible gene P450 1A1 in FL/P450 1A1 cell
     硫酸镉对FL/P4501A1细胞中人肺癌易感基因P4501A1的影响
短句来源
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  expression of p
     Detection of expression of p21 gene in neuroblastoma
     神经母细胞瘤细胞周期调控基因p21的表达检测
短句来源
     Through detecting the expression of p53, p14ARF, Rb, p16INK4a and p33INGlb genes in t (8; 21) AML, explore the correlation of these genes with the disease, and provide the clue for deeply investigating the pathogenesis of t(8;21) AML.
     检测p53、Rb及其通路相关基因p14ARF、p16INK4a和p33INGlb在t(8;21)AML的表达和/或缺失情况,探讨这些基因与t(8;21)AML的相关性,为深入研究t(8;21)AML的发生机制提供线索。
短句来源
     Expression of P21~(WAF-1) of Neuron in Second-actue Brain Aging Models
     急性脑老化模型大鼠脑神经元中衰老基因p21~(WAF-1)的表达
短句来源
     Methods Using nested reverse transcription-PCR to analyze the expression of P57KIP2,LIT1,TSSC3 in human oocytes and preimplantation embryos.
     方法应用嵌套式逆转录聚合酶链反应技术检测印记基因P57KIP2、LIT1、TSSC3在人类卵母细胞及植入前胚胎的正常表达。
短句来源
     Expression of p16 and Cyclin D_1 in uterine endometrial carcinomas and its significance
     基因p16及CyclinD_1在子宫内膜癌中的表达及意义
短句来源
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  “基因p”译为未确定词的双语例句
     Studies of P53/MDM2/P21 and HBV Correlation in Hepatoma Cells
     肝癌细胞中肿瘤基因P53/MDM2/P21与HBV关系的研究
短句来源
     Expression and Significance of p53、Rb and Their Pathways Correlated Genes p14ARF、p16INK4a and p33ING1b in Acute Myeloid Leukemia with t(8;21)
     p53、Rb及其通路相关基因p14ARF和p16INK4a、p33ING1b在t(8;21)AML中的表达及意义
短句来源
     Investigation the Relationship between P1A1/ P1A2 Polymorphism of the Platelet Glycoprotein ReceptorⅢ a Gene and Myocardial Infarction
     血小板受体GPⅢa基因P1A1/P1A2多态性与心肌梗塞关系的研究
短句来源
     Aims: To appraise the expressions of drug resistance-associated genes, such as p21(WAF1/CIP1), MRP2, BRCA2, CYP3A5, BCRP and ELK-1 in human colonic carcinoma at the transcriptional level and their significance.
     目的:探讨人结肠癌组织中耐药相关基因p21(WAF1/CIP1)、MRP2、BRCA2、CYP3A5、BCRP和ELK-1转录水平的表达及其临床意义。
短句来源
     Study of Apoptosis and Expression of Apoptotic Related Genes P53,bcl-2,C-myc in Oral Lichen Planus
     口腔扁平苔藓患者细胞凋亡及凋亡相关基因p53、bcl-2、C-myc的表达
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  gene p
For a quarter of a century the gene p53 has attracted close attention of scientists who deal with problems of carcinogenesis and maintenance of genetic stability.
      
Mutations in the tumor suppressor gene p53 often lead to disarrangement of the cell cycle and of genetic integrity control of cells that may contribute to tumor development.
      
A modulation of the p53 target gene (p21/WAF,bax,mdm-2, and thrombospondin-1) expression was observed upon Mts1 induction in the cells expressing the wild-type p53.
      
The results showed that HCC was closely correlated to methylation in promoter of tumor-suppressing gene p16, p53, SFRP1 and SFRP2.
      
In 44 patients with negative lymph node, 9 cases progressed to distant metastasis, 7 of them (77.8%) showed low expression of nm23 gene (P>amp;lt;0.05).
      
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  expression of p
Further, manzamine A (50 μM) substantially down regulated the expression of p53 while sarcophine (50 μM) slightly induced the level of p21.
      
In conclusion, the present results show that the host-vector system used is suitable for high-level functional expression of P-45017α and further application of enzymatic properties of this protein to perform specific steroid biotransformations.
      
Enhanced expression of p73 mRNA in tumor tissue compared with normal bronchogenic epithelium was found in 28 of 34 (82.4%) NSCLC patients.
      
Expression of p73 in NSCLC cells showed correlation neither with deletions of one of the alleles, nor with any parameter reflecting clinical pathology.
      
Transcriptional activity and expression of p53 proved to depend on the proportion between p53 and GSE22.
      
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We have construeted a universal vector pGJP-5 for gene expression in vaccinia virus. A low side-effect Chinese strain, Guang-9, was utilized as a starting virus. The thymidine kinase (TK) gene of Guang-9 in the vector provided not only the homologous sequences for in rive recombination with the vaccinia virus genome, but a so the selective marker for the virus recombinants. The promoter of the gene coding for vaccinia viral 7.5 K protein (P_(7.5)) was inserted into the TK structure gene. On the downstream side...

We have construeted a universal vector pGJP-5 for gene expression in vaccinia virus. A low side-effect Chinese strain, Guang-9, was utilized as a starting virus. The thymidine kinase (TK) gene of Guang-9 in the vector provided not only the homologous sequences for in rive recombination with the vaccinia virus genome, but a so the selective marker for the virus recombinants. The promoter of the gene coding for vaccinia viral 7.5 K protein (P_(7.5)) was inserted into the TK structure gene. On the downstream side of P_(7.5), several restriction sites, BamHI, Sinai, SaeI, EcoRI, were arranged for the insertion of the foreign genes. The inserted foreign gene can be expressed efficiently under the control of the promoter P_(7.5).

我们从弱毒的痘苗病毒广-9株出发,构建了一个通用的痘苗病毒表达载体pGJP-5。广-9株的胸腺嘧啶核苷激酶(TK)基因既作为表达载体与痘苗病毒基因组体内重组的同源顺序,又作为重组病毒的筛选标记。在TK结构基因中插入了编码痘苗病毒7.5K蛋白基因的启动基因(P_(7.5)),它可以有效地启动外源基因在痘苗病毒中表达。同时启动基因P_(7.5)的3′末端有BamHⅠ、SmaⅠ、SacⅠ和EcoRⅠ的限制性内切酶位点可供外源基因插入。

Seeds of severval generations of seven crosses between an apetalous line APL-0256 and seven normal cultivars of rapeseed (Brassica napus L.) were sown in the autumn of 1988 and spring of 1989, in order to study the inheritance of the apetalous character. A tetrapetalous iso-genic line of APL-0256 and a high-yielding conventional cultivar Ningyou 7 were used as controls to evaluate the floral morphogenesis, photo-synthetic physiology, disease resistance and breeding potentials of the apetalous trait.

将正常品种与无花瓣亲本杂交,正反交F_1代中有瓣对无瓣为完全显性。在F_2及B_1中,有瓣:无瓣分别为255:1与15:1,表明无花瓣性状的遗传受着核中四对隐性基因p_1p_1p_2p_2p_3p_3p_4p_4的制约。无花瓣基因的育种价值主要体现在减耗节能,包括个体节能(减少建成花瓣的损耗)和群体节能(降低黄色冠层对自然光的吸收与反射损失),以及对菌核病的形态避病能力(田间发病率仅为1.75%)。

DNA restriction fragment length polymorphisms (RFLPs) of apo A********I-C********III-gene cluster had been determined using Pst ******I , Sst ********I , and EcoR *******I among healthy persons of Han Nationality in Guangdong, China.The frequencies of the P1, P2, S1,S2,R1,and R2 alleles are 0.98, 0.02, 0.96, 0.04, 0.90, and 0.10, respectively.They are consistent with Hardy-Weinberg equilibrium by Chi-Square test.Compared the results with other reports shows a large difference in alleles frequency among the races.In...

DNA restriction fragment length polymorphisms (RFLPs) of apo A********I-C********III-gene cluster had been determined using Pst ******I , Sst ********I , and EcoR *******I among healthy persons of Han Nationality in Guangdong, China.The frequencies of the P1, P2, S1,S2,R1,and R2 alleles are 0.98, 0.02, 0.96, 0.04, 0.90, and 0.10, respectively.They are consistent with Hardy-Weinberg equilibrium by Chi-Square test.Compared the results with other reports shows a large difference in alleles frequency among the races.In Han Nationality of Guangdong, China, the frequencies of P2 allele is lower than those of Japanese, Indian Asians, and Caucasians, the S2 allele frequence is lower than those of Japanese, Saudi Arabians,and Indian Asians, and near those of Caucasians, and the R2 allele frequence is higher a little bit than those of Caucasians.The reasons of these differences may be genetic drift or natural selection operating at this gene cluster, or a combination of both.Haplotypes identified by DNA RFLPs in this gene cluster are linkage disequilibrium.

本文研究了中国广东汉族健康人群apoAI-CⅢ-AIV基因簇DNA限制性内切酶PstI、SstI和EcoRI片段长度多态性。其中等位基因P_1,P_2,S_1,S_2,R_1和R_2的频率分别为0.98,0.02,0.96,0.04,0.90和0.10。经卡方检验符合Hardy-Weinbery氏遗传平衡,与其他种族比较,本文结果显示中国广东汉族人P_2等位基因频率低于日本人、亚洲印第安人和高加索人,S_2等位基因频率低于日本人、菲律宾人、沙特阿拉伯人和亚洲印第安人,而与高加索人相近,R_2等位基因频率稍高于高加索人。不同种族间apoAI-CⅢ-AIV基因簇DNA多态频率无疑存在差异,这种差异可能是由于遗传漂变和自然选择单独或联合作用所致。对P_1、P_2,S_1、S_2和R_1、R_2构成的单倍型和连锁平衡程度进行了分析,结果显示这些单倍型处于连锁不平衡状态。

 
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