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    Conclusion A significant positive correlation exist between the expression of Tiam1 and the gastric carcinoma infiltration and metastasis as well as among kinds of clinical pathological factors, so the expression of Tiam1 can provide valuable reference for the prevention of infiltration, metastasis and the decision of prognosis.
    结论Tiam1蛋白的表达与胃癌浸润转移呈相关关系,并与多种临床病理因素相关,可为胃癌浸润转移的防治和病人的预后判定提供有价值的参考。
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    The mechanism,which wasn't dependent on COX-2 expression,may provide the experimental evidence for nimesulide used for the prevention and treatment of the metastatic breast cancer.
    结论:nimesulide以剂量依赖性方式下调MDA-MB-231、MCF-7乳腺癌细胞株MMP-2、MMP-9mRNA的表达,而MDA-MB-231细胞对nimesulide更敏感,这种作用是COX-2非依赖性途径,为nimesulide用于转移乳腺癌的治疗与预防提供了实验依据。
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    Objective To analyze the change of trend and regulation of incidence age of patients with cervical cancer in Yichang city from 1982 to 2004,and to provide scientific basis for prevention and treatment of cervical cancer.
    目的分析1982~2004年宜昌地区宫颈癌发病年龄变化趋势与规律,为宫颈癌防治提供科学依据。
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    Conclusion The positive rate of PCNA is related with the positive or negative expression of ER,PR in breast cancer. Associating PCNA with ER,PR detection can provide the ancillary evidence to predict the prognosis and to formulate the treatment plan of endocrinetherapy after breast cancer operation.
    结论PCNA阳性表达率与ER、PR阳性或阴性结果有关,PCNA与ER、PR联合检测,可为乳腺癌术后内分泌治疗方案的制定和预测预后提供辅助依据。
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    Objective To explore the association of cytochrome P450(CYP)1A1 and glutathione S-transferase(GST) M1 gene polymorphism and frequent risk factors to the susceptibility of gastric cancer in Chinese Han ethnic group, and to provide molecular methods to define the high risk population of gastric cancer for primary prevention.
    目的探讨中国汉族人群细胞色素P450(CYP)1A1基因型、谷胱甘肽巯基转移酶(GST) M1基因型及常见危险因素与胃癌易患性的关系,为胃癌高危人群的确定和胃癌的一级预防提供分子生物学手段。
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    Conclusion: Functional expression of TAp63γ under Dox induced Tet-on regulation system have been successfully established in EC9706, which provides an ideal experimental platform for the further study of TAp63γ in esophageal squamous carcinoma cell.
    结论:成功构建了Tet-on调控TAp63γ基因表达的EC9706细胞系,为进一步研究食管鳞癌细胞内P63蛋白的生物学行为提供了一个理想的研究平台。
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    COX-2 maybe provides a new way to predict breast cancer risk,prevention and treatment of breast cancer.
    结论:COX-2在乳腺癌的演变过程中起重要作用; COX-2可能为乳腺癌的发病风险的预测和乳腺癌的预防与治疗提供一条新的途径。
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    Conclusion:The best transfection dose of TNFR2 is 5 μg and can reach its peak in 48 h so it provides basic proof for the genetic treatment of the laryngeal squamous cacinoma.
    结论:TNFR2的最佳转染剂量为5μg,48 h可达高峰。 此结果为喉鳞癌的基因治疗提供了依据。
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    Conclusion Ad-VEGF-siRNA can inhibit the expression of VEGF in the osteosarcoma tissues,and this provides theoretical basis for the osteosarcoma vessels targeting therapy with RNA interference technology.
    结论腺病毒介导的VEGF-siRNA能够抑制骨肉瘤组织中VEGF的表达,为RNA干扰技术靶向血管治疗骨肉瘤提供了理论可能。
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    RNA interference (RNAi) technique emergence provides a new way to inhibit gene expression.
    RNA干扰 (RNA interference, RNAi ) 技术的出现为我们抑制基因表达提供了一种新的思路。
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    Objective To analyze the change of trend and regulation of incidence age of patients with cervical cancer in Yichang city from 1982 to 2004,and to provide scientific basis for prevention and treatment of cervical cancer.
    目的分析1982~2004年宜昌地区宫颈癌发病年龄变化趋势与规律,为宫颈癌防治提供科学依据。
短句来源
    Objective To explore the association of cytochrome P450(CYP)1A1 and glutathione S-transferase(GST) M1 gene polymorphism and frequent risk factors to the susceptibility of gastric cancer in Chinese Han ethnic group, and to provide molecular methods to define the high risk population of gastric cancer for primary prevention.
    目的探讨中国汉族人群细胞色素P450(CYP)1A1基因型、谷胱甘肽巯基转移酶(GST) M1基因型及常见危险因素与胃癌易患性的关系,为胃癌高危人群的确定和胃癌的一级预防提供分子生物学手段。
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    Objective:To provide new evidence for understanding the biological behavior of primary ovarian carcinoma,the expression of basic fibroblast growth factor(bFGF)and E26 transformation-specific-1(Ets-1)was detected in primary ovarian carcinoma.
    目的检测碱性成纤维细胞因子(bFGF)和E26转录因子(Ets-1)在卵巢癌中的表达,为评估卵巢癌的生物学行为提供新的依据。
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    Objective:To study the effects of the expression of P21WAF1, MDM-2 and Rb on growth in pancreatic carcinoma, in order to provide some valuable evidences for prognosis.
    目的:探讨P21WAF1、MDM-2、Rb在胰腺癌发生过程中的作用,为预后判断提供理论依据。
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    Objective: To investigate protein expression in the molecular subtypes of diffuse large B-cell lymphoma (DLBCL), so as to provide discernible markers for the pathological diagnosis, treatment and prognosis of DLBCL.
    目的:在蛋白水平上研究国人弥漫性大B细胞淋巴瘤(diffuse large B-cell lymphoma,DLBCL)分子分型的蛋白表型特点,为DLBCL的病理诊断、预后和治疗提供依据。
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    Specific short chain oligonucleotide was designed using the RNAi software according to the mRNA sequence provided by GeneBank,the oligonucleotides was gained through annealing after chemosynthesis and was inserted into HindⅢ/BglⅡlinearized pSUPER-neo-EGFP/H1(pSNE/H1)plasmids. The recombinant expression vector was evaluated using enzyme cutting and sequencing.
    根据GenBank提供的ILK基因mRNA序列,设计具有小发夹结构的两条DNA序列,化学合成后经退火形成双链DNA片段,连接到经HindⅢ/BglⅡ酶切线性化的pSUPER-neo-EGFP/H1(pSNE/H1)质粒上,形成重组载体pSNE-ILK,转化大肠杆菌DH5α,提取质粒经HindⅢ/EcoRⅠ双酶切鉴定和测序鉴定,稳定转染结肠癌细胞HT29。
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    Conclusion rAAV-HPV16E7AS was successfully constructed,which provided a novel route to prevention and treatment of cervical cancer.
    结论已成功构建rAAV-HPV16E7AS,为临床预防和治疗子宫颈癌提供新的手段。
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    ①Hela cells were cultured in vitro and exposed to radiation from 169Yb and 125I seeds(provided by Department of Isotopes,China Institute of Atomic Energy)which were put into the culture solution respectively to observe the killing range of the radiation.
    ①采用Hela细胞体外培养,169Yb和125I(由中国原子能研究院同位素所提供)分别置入培养液中照射细胞,观察射线对细胞杀伤范围。
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    Methods ACC-M cells were provided by Shanghai Second Medical University. Matrine was produced by Guangzhou Mingxing Medicine Factory.
    材料与方法ACC-M 细胞由上海第二医科大学口腔医学院提供,苦参碱由广州明兴制药厂生产,ACC-M 细胞培养于普通RPMI-1640培养基中。
    The research drug was rh-Apo2L provided by Shanghai TRAIL Biotechnology Limited Company.
    试验药品rh-Apo2L由上海恰尔生物技术有限公司提供
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Gindikin that complex analytic objects related to these domains will provide explicit realizations of unitary representations ofH?.
      
Here we provide certain conditions (more general than those in [Ka1]) which guarantee preservation of the topology under a modification.
      
We investigate conditions on kernel operators in order to provide prescribed orders of approximation in the Triebel-Lizorkin spaces.
      
We provide a direct computational proof of the known inclusion ${\cal H}({\bf R} \times {\bf R}) \subseteq {\cal H}({\bf R}^2),$ where ${\cal H}({\bf R} \times {\bf R})$ is the product Hardy space defined for example by R.
      
The space spanned by the translates of φv can only provide approximation order if the refinement maskP has certain particular factorization properties.
      
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As a result, this provides new examples of weakly symmetric spaces that are nonsymmetric, including those already discovered by Selberg (cf.
      
This provides a generalization of results of [9], [7], [6].
      
An important example is the Moser-Trudinger inequality where limiting Sobolev behavior for critical exponents provides significant understanding of geometric analysis for conformal deformation on a Riemannian manifold [5, 6].
      
This factorization provides an alternative for the lattice factorization, with the advantage that it can also be used in the biorthogonal, i.e., non-unitary case.
      
This provides a contrast with the existing comparison between the Heisenberg group itself and Euclidean space in terms of Pompeiu sets.
      
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We investigate conditions on kernel operators in order to provide prescribed orders of approximation in the Triebel-Lizorkin spaces.
      
We use these unitary operators to provide an interesting class of scaling functions.
      
Starting with isovanillin, a two-step sequence involving reductive amination and N-benzylation was performed to provide the compounds in good purity.
      
Each NMR spectra was data-processed to provide 238 intensity-related descriptors as input coordinates in a multidimensional space and analyzed by PR method.
      
Capillary with inner diameter of 100 μm increased the intensity of determination; therefore, color dyes were identified in the visible range and were able to provide more information for comparing types of roller pen inks.
      
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When p is finite, a sequence {λn} of complex numbers will be called aframe forEp provided the inequalities hold for some positive constants A and B and all functions f inEp.
      
The same is true for frequency modulation provided the symbol of the operator is piecewise continuous.
      
Similar result holds for the derivatives of refinable function vectors provided that the dilation matrix is diagonalizable.
      
Doses ranging from 12.5-50 μM provided a dose-dependent reduction in the number of viable cells when compared to controls.
      
In addition, several equivalent characterizations of multivariate exponential distribution are provided in the multivariate HNBUE life distribution class which include many existing results as special cases.
      
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