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   基因预测 的翻译结果: 查询用时:1.245秒
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基因预测
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  gene prediction
     Gene Prediction and Function Research of SARS-CoV(BJ01)
     SARS-CoV(BJ01)基因预测及功能推测
短句来源
     An Analysis of the Measures for Gene Prediction Accuracy
     基因预测准确性的度量标准分析
短句来源
     Gene prediction was carried out with a ctgl6 flanking context of 7250 bp on P. chrysosporium genome, from which a 6083 bp gene with a 3921 bp coding sequence and a putative peptide called Ctgl6pr of 1306 amino acids was deduced.
     对该序列在黄孢原毛平革菌基因组中同源序列上下游7250bp的区域进行基因预测,得到一个长6083bp的基因及编码1306aa的3921bp开放阅读框(ORF)。
短句来源
     It turns out that this algorithm can improve the precision of the gene-prediction, and puts forward a possible way for the future research in gene prediction.
     实验结果表明该算法提高了基因预测的精度,提供了一种可能的研究基因预测方案。
短句来源
     Gene prediction is an important research branch in the field of bioinformatics.
     基因预测是生物信息学领域中的一个重要研究方向。
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  gene finding
     HumGene:A Human Gene Finding Program Based On Generalized Hidden Markov Model
     HumGene:一个基于GHMM的人类基因预测软件
短句来源
     HumGene is a human gene finding program based on generalized hidden Markov model (GHMM). Usually, GHMM algorithm can't be used in human gene finding software directly because of its huge computation.
     HumGene是一个采用广义隐Markov模型(GHMM)的人类基因预测软件.
短句来源
  predicted genes
     Using twelve gene prediction methods to predict coronavirus known genes,we select four better methods including Heuristic models,Gene Identification,ZCURVECoV and ORF FINDER to predict SARS-CoV(BJ01),and use ATGpr for analyzing probability of initiation codon and Kozak rule,search transcription regulating sequence(TRS)in order to improve the accuracy of predicted genes.
     比较 12种基因预测方法对冠状病毒属中已知基因的预测优劣 ,选用Heuristicmodels、GeneIdentification、ZCURVECoV和ORFFINDER 4种较好的方法来预测基因 ,然后运用AT Gpr分析第一起始密码子的可能性及是否符合Kozak规则 ,同时搜索转录调控序列 ,以提高基因预测的准确性。
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  “基因预测”译为未确定词的双语例句
     A neuro-fuzzy inference model with structure learning
     具有结构学习的神经模糊推理模型及其在fRNA基因预测中的应用
     Combining Gene Predictions Using Dempster-Shafer Theory of Evidence
     基于Dempster-Shafer证据理论的组合基因预测
短句来源
     A gene-prediction algorithm based on the statistical combination and the classification in terms of CpG content
     基于统计组合与CpG含量分类的基因预测算法
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     Sequence analysis of thisregion revealed that ORF4, 5, 6, 7 and 8 could be the candidates of Xa23 gene.
     7.使用RiceGAAS软件对阳性BAC克隆序列进行基因预测,确定ORF4、5、6、7和8是候选基因。
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     Research on Information Processing Methods for Gene-Prediction
     面向基因预测的信息处理方法研究
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  gene prediction
Gene prediction of 74-kb region carrying the pla1 locus suggested several candidate genes for the pla1 gene.
      
Automatic gene prediction was not efficient because of the poor ability of the programs used to recognize the short exons encoding the intracellular regions of TSSs.
      
sRNAFinder is a new gene prediction system for systematic identification of noncoding genes in bacteria.
      
sRNAFinder incorporates heterogeneous data sources for gene prediction, including primary sequence data, transcript expression data from microarray experiments, and conserved RNA structure information as determined from comparative genomics analysis.
      
fumigatus by comparative analysis with four other fungal species and the gene prediction program GlimmerM.
      
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  gene finding
Furthermore, we demonstrate that a local structural alignment can be employed for ncRNA gene finding.
      
Gene Finding on the Y: Fruitful Strategy in Drosophila does not Deliver in Anopheles
      
Automated methods for identifying protein coding regions in genomic DNA have progressed significantly in recent years, but there is still a strong need for more accurate computational solutions to the gene finding problem.
      
Large-scale genome sequencing projects depend greatly on gene finding to generate accurate and complete gene annotation.
      
Improvements in gene finding software are being driven by the development of better computational algorithms, a better understanding of the cell's mechanisms for transcription and translation, and the enormous increases in genomic sequence data.
      
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  predicted genes
The search in the 250-kb region overlapping the locus of this gene (sections 88E-89B) and containing 78 predicted genes has revealed only one gene,CG17604, whose protein meets all requirements for the transverse filament protein of the SC.
      
BLASTN and BLASTX analysis of the sequences flanking mapped SSRs indicated that a majority (84%) are derived from non-genic sequences, with a small proportion corresponding to either known repetitive DNA sequence families or predicted genes.
      
By assaying the recombinant events in the region with markers developed using the sequence information, the f5 locus was further narrowed down to a 70?kb fragment containing nine predicted genes.
      
By two-step substitution mapping, gpa7 was finally narrowed down to a 35-kb region that contains five predicted genes in cultivated rice.
      
Several of the predicted genes in the region are homologous to disease resistance loci, including one NBS-LRR resistance gene analogue that is present in multiple tandem copies.
      
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The conserved region of Ran Binding Protein RanBP1 was used as a probe to screen the human retina cDNA library under low stringency. A positive clone named M3 was obtained, which was highly homologous to zhx 1 gene in M. musculus. The gene was positioned to the region of 8q24.11 q24.3 by RH mapping. The full length of the M3 cDNA(obtained by EST assembling)was 4 934 bp, corresponding to that of the main transcript shown in Northern bolt. This cDNA sequence included an open reading frame of 2 622 bp(coding...

The conserved region of Ran Binding Protein RanBP1 was used as a probe to screen the human retina cDNA library under low stringency. A positive clone named M3 was obtained, which was highly homologous to zhx 1 gene in M. musculus. The gene was positioned to the region of 8q24.11 q24.3 by RH mapping. The full length of the M3 cDNA(obtained by EST assembling)was 4 934 bp, corresponding to that of the main transcript shown in Northern bolt. This cDNA sequence included an open reading frame of 2 622 bp(coding for 873 aa) and two kinds of translation modules uAUG and TTATTTAT. The predicted protein had two C 2H 2 zinc finger structures, five homeodomains, one bipartite nuclear localization signal(NLS) and 35 potential phosphorylation sites, which all suggested that M3 gene may both function as transcriptional regulator and be regulated by other upstream factors.

以Ran结合蛋白RanBP1的保守区域作为探针 ,低严谨条件下杂交筛选人视网膜cDNA文库 ,得到阳性克隆M 3,它与鼠zhx 1基因高度同源 .RH作图将其定位于 8q2 4.11~q2 4.3.拼接EST序列并填补缺口 ,得到M 3cDNA全长 4934bp ,与Northernblot得到的主要转录本长度一致 .此cDNA全序列包括 2 6 2 2bp开放阅读框 ,编码 873氨基酸 ,含有 2种翻译调控元件uUAG和TTATTTAT .该基因预测蛋白含有 2个锌指结构 ,5个同源盒保守区 ,1个双侧核定位序列 (NLS)及 35个磷酸化位点 ,表明它既可能作为转录调控因子 ,也可能受到上游因子的调控 .

With the completion of Human Genome draft,bioinformatic research has entered the post genomic era.Studying of the control of gene expression and function using computational methods has gradually become the mainstream of research.For its special role in the control of eukaryotic gene expression,alternative splicing has become an important topic in genomic research.In this study,we analyzed alternative splicing of human genes based on complete coding sequences (cds) of alternatively spliced genes.As reported...

With the completion of Human Genome draft,bioinformatic research has entered the post genomic era.Studying of the control of gene expression and function using computational methods has gradually become the mainstream of research.For its special role in the control of eukaryotic gene expression,alternative splicing has become an important topic in genomic research.In this study,we analyzed alternative splicing of human genes based on complete coding sequences (cds) of alternatively spliced genes.As reported previously we have set up a database AsMamDB.Transcripts probably belonging to one gene were put into a single cluster.We also developed a new multi alignment tool,ASALIGN,aiming to reveal alternative splicing patterns of transcripts belonging to a same gene and identify their alternative and non-alternative regions.Here,through filtering we chose 371 genes that have two or more different cds.Using Asalign we have identified all alternatively spliced regions in the cds of selected genes.We also studied lengths,positions of alternatively spliced regions,shifting of reading frames due to alternative splicing,as well as codon frequencies of non alternative,alternatively spliced regions and their boundaries,and ended with some interesting results.Our study may provide important insights into the alternative splicing phenomenon and clues for prediction of alternative splicing.

随着人类基因组计划 (HGP)的完成 ,生物信息学的研究进入了后基因组时代 ,用计算方法对基因表达调控和基因功能进行研究成为生物信息学研究的核心内容 .由于在真核基因表达调控中的特殊地位 ,选择性剪接成为研究真核基因表达调控的重要内容之一 .本文从收集选择性剪接基因的数据出发 ,尽可能的收集已知的选择性剪接的基因和它们的各种转录产物 ,并进行了适当的筛选以保证数据的质量和统计分析的可靠性 .对挑选出的 371个人类基因 ,提取各种转录产物的编码区 (codingregions,或简称cds) ,应用一种新的针对选择性剪接的多序列比对程序ASALIGN进行多序列比对来揭示不同cds间的剪接关系 ,提出其中的可变区域与不可变区域 ,并对可变区域与不可变区域的长度分布 ,可变区域在cds中出现的位置 ,由于选择性剪接引起的同一段序列读码框相位的变化以及可变区域与不可变区域及二者边界上的密码子使用频率进行了统计分析 ,得到了一些很有意思的结果 .这些统计结果对于选择性剪接机制的进一步研究以及选择性剪接基因的预测提供了良好的线索

Sequencing analysis of the 323 kb contig of rice chromosome 4 identified a gene cluster encoding 7 dihydroflavonol-4-reductase (DFR)-like proteins within a 56 kb region. The 7 DFR-like genes were found to be arranged in a tandem array, and all of them comprised 6 exons and 5 introns. Analysis of the predicted amino acid sequences demonstrated that these 7 proteins shared strong similarities with DFR and other enzymes of the phenylpropanoid biosynthesis pathway. RT-PCR revealed the expression pattern of the 7...

Sequencing analysis of the 323 kb contig of rice chromosome 4 identified a gene cluster encoding 7 dihydroflavonol-4-reductase (DFR)-like proteins within a 56 kb region. The 7 DFR-like genes were found to be arranged in a tandem array, and all of them comprised 6 exons and 5 introns. Analysis of the predicted amino acid sequences demonstrated that these 7 proteins shared strong similarities with DFR and other enzymes of the phenylpropanoid biosynthesis pathway. RT-PCR revealed the expression pattern of the 7 genes was different in various rice tissues. The structural and functional features of these 7 DFR-like genes and their evolutionary implications are discussed.

通过对水稻 4号染色体一段 32 3kb的序列测定和分析 ,在其中 56kb的区域内发现了一个由 7个编码二氢黄酮醇还原酶 (DFR)类似蛋白基因组成的基因簇。这 7个基因在基因簇中串联排列 ,每个基因都由 6个外显子和 5个内含子组成。这 7个基因的预测蛋白质序列都和DFR以及BANYULS蛋白序列类似。DFR和BANYULS都是植物次生代谢类黄酮醇生物合成途径中的结构基因 ,它们的缺失或突变都会造成植物花色素合成代谢的不正常。RT PCR实验证明这 7个基因在水稻的 5个组织中表达不同。文中讨论了这 7个基因的结构和功能特性以及它们的进化关系。

 
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