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     the Tmax (h), Cmax(ug/ml), AUCo-t(ug/ml.h) of isoniazid were 1.32 ± 0.64 ,8.78 ± 3.63, 28.77 ± 20.74(tested group) and 1.07 ± 0.51, 10.03 ±4.64, 30.97 ± 22.81 (control group);
     异烟肼的Tmax(h)、Cmax(ug/ml)、AUCo-t(ug/ml.h)分别为1. 32±0. 64、 8. 78±3. 63、 28. 77±20. 74(试验药)和1. 07±0. 51、 10. 03±4. 64、 30. 97±22. 81(参比药);
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     On the other hand,commercially available bezafibrate sustained tablets(reference tablets) were:t_(max)(4.1±0.4)h,c_(max)(39.66±0.94 )μg/mL,AUC_(0-∞)(327.27±8.97)μg·h/mL.
     h/mL; 苯扎贝特缓释片(参比片)的tmax(4.1±0.4)h,cmax(39.66±0.94)μg/mL,AUC0-∞(327.27±8.97)μg.
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     Methods A single oral dose(5 mg of Glipizide and 500 mg of Metformin hydrochloride) was given to volunteers.
     方法单剂量给予国产的复方格列吡嗪片505mg(试验制剂)和格列吡嗪片5 mg(参比制剂)、盐酸二甲双胍片500 mg(参比制剂)。
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     AIM: To evaluate the bioequivalence between recombinant human growth hormone (rhGH) injection(2 standard: T1 and T2)and rhGH for injection(R).
     目的:评价重组人生长激素(rhGH)注射液(2种规格:T1和T2)与注射用rhGH冻干粉针剂(参比制剂,R)的人体生物等效性。
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     METHODS: This is an open randomized , three period crossover study on twenty four healthy volunteers after a single oral dose of 80 mg valsartan as tablet (T 1),capsule(T 2) and reference (R).
     方法 :2 4名健康男性受试者采用三制剂三周期随机交叉试验设计 ,分别口服单剂量 80mg缬沙坦片剂 (被试制剂T 1)、胶囊 (被试制剂T 2 )和缬沙坦胶囊 (参比制剂R)。
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     A Silver-Silver Chloride Reference Electrode
     AglAgCl电极的研制
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     Study on Solid State Reference Electrode
     固体电极的研究
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     ,10refs.
     10。
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     10refs.
     10。
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     V. C higher than families G.
     V.C家系G.
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The authors extend and improve some known results, and show that there are some errors in reference on inequalities for sequence rearrangement by examples.
      
The blank reference experiment shows that hydrothermal crystallization treatment favors the formation of hexagonal tungsten trioxide, and the tungsten trioxide powder sample prepared by this method has a high degree of crystallinity.
      
This paper provides a reference on calculating the binding-site number in proteins for ligands and studying their interactions by fluorescence spectroscopic methods.
      
The proposed algorithm can easily identify which sector the reference space vector falls in and conduct simple operations to find the duty cycle of each vector.
      
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An improved potentiometric method for determination of chloride ions with mercuric nitrate is described. Silver-silver chloride electrode is used as the indicating electrode while the reference electrode is a silver-electrode, immersed in 0.1 N silver nitrate solution. The addition of an amount of ethyl alcohol, which equals to 74% of the total volume of solution at the end of titration, is advocated. Satisfactory results are obtained. Variations in concentration of mercuric chloride at the end point and pH...

An improved potentiometric method for determination of chloride ions with mercuric nitrate is described. Silver-silver chloride electrode is used as the indicating electrode while the reference electrode is a silver-electrode, immersed in 0.1 N silver nitrate solution. The addition of an amount of ethyl alcohol, which equals to 74% of the total volume of solution at the end of titration, is advocated. Satisfactory results are obtained. Variations in concentration of mercuric chloride at the end point and pH of solution have no effect on titration results. Owing to the fact that no precipitate is formed during the titration, this method is easier to carry out than the argentometry.

本文讨论硝酸汞电位滴定法,用氯化银电极为指示电极,用银电极浸入0.1N硝酸银溶液中为参比电极,在试液中加入相当於滴定终了时总体积74%的乙醇,滴定可得到较硝酸银电位法更为令人满意的结果。

The electrochemical method for the determination of metal chelate stability constants by means of potentiometric measurement with a mercury electrode has been applied to EDTA complexes of divalent metals at 30.0±0.1°in the presence of potassium nitrate. The basic principle of this method is based upon the exchange equilibria of the type

本文改进Schwarzenbach和Reilley等所用的方法,用汞电极测得多种二价金属(Hg,Cu,Pb,Zn,Cd,Mn,Ca,Mg,Sr,Ba)的乙二胺四乙酸螯合物的稳定常数,结果见表5.实验条件:t=30.0±0.1°,μ=0.1,参比电极是0.1 M Ag-AgCl电极.溶液的组分浓度是 Hg:0.001 M HgY~(2-)+0.001 MY~(4-) Cu,Pb,Zn,Cd:0.0001 MHgY~(2-)+0.01 MMeY~(2-)+0.001 MMe~(2+) Zn,Cd,Mn,Ca,Mg,Sr,Ba:0.001 M HgY~(2-)+0.001 MMeY~(2-)+0.001 MMe~(2+) Schwarzenbach主张在测试溶液中预加若干金属汞,而Reilley等则未加.本文对CaY~(2-)作加汞与不加汞的试验,证明加汞并非必要.达到平衡的时间,无论加汞与否,都为十六小时.

The results obtained from the spectraphotometric determinationof the complex of Tecl_5~- and butylrhodamine B with TBP—C_6H_6solution extraction are recommended as follows: (1) The concentration of hydrochloric acid is 4—6 N and butyl-rhodamml B (0.5%) 4 — 6ml. The absorbance of the organic layer ismeasured at 540nm using a reagent blank as a reference. (2) The molar extinction coefficient of the complex is 6.4×10~4,the ion - pair complex of compositon is Tecl_5~-·R~+. (3) The extraction reaction: Te~(4+) +...

The results obtained from the spectraphotometric determinationof the complex of Tecl_5~- and butylrhodamine B with TBP—C_6H_6solution extraction are recommended as follows: (1) The concentration of hydrochloric acid is 4—6 N and butyl-rhodamml B (0.5%) 4 — 6ml. The absorbance of the organic layer ismeasured at 540nm using a reagent blank as a reference. (2) The molar extinction coefficient of the complex is 6.4×10~4,the ion - pair complex of compositon is Tecl_5~-·R~+. (3) The extraction reaction: Te~(4+) + H~+ + Cl_5~-?HTeCl_5 TeCl_5~- + R + ? [TeCl_5~-·R+] The exrtaction equilibrium constant is 1×10~5. (4) The effects of a number of foreign ions have been studied andseveral can be tolerated to an appreciable extent. The method hasbeen successfully applied to the determination of Te in SeO_2.

介绍用TBP——苯溶液萃取光度测定Tecl_5~-与丁基罗丹明B终合物的如下结果: (1)盐酸浓度为4——6N,丁基罗丹明B(0.5%)4——6mI以试剂空白为参比在540nm处测量有机层的吸收。 (2)络合物克分子吸光系数为6.4×10~4,离子对络合物组成为Tecl_5~-.R~+。 (3)萃取反应为: Te~(4+)+H~++Cl_5~-?MHTeCl_5 TeCl_5~-+R+?[TeCl_5~-.R~+]萃取平衡常数为1×10~5. (4)研究了干扰离子的影响及其允许量;该方法已成功地用于二氧化硒中碲的分 离和测定。

 
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