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所有小鼠
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  all the mice
     All the mice were treated with 1 mg/kg aqua fortis scopolamine by subcuta-neous injection, and 30 minutes later the mice in the seizure-induced group were treated with 350 mg/kg(10 g/L) pilocarpine by intraperitoneal injection, and those in the saline group were treated with 35 μL/g saline by intraperitoneal injection.
     所有小鼠皮下注射硝酸东莨菪碱1mg/kg,30min后致痫组腹腔注射毛果芸香碱350mg/kg(10g/L),生理盐水组腹腔注射生理盐水35μL/g。
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     From the first day of experiment, all the mice were treated with 5 g/L cyclophosphamide solution by intraperitoneal injection for successively 5 days, 6 mL/kg per day.
     所有小鼠于实验第1天起,连续5d腹腔注射5g/L环磷酰胺溶液,剂量为6mL/(kg·d)。
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     At day 20, all the mice were killed to obtain bone marrow cells of one side femoral bone of mice. The smear received bcl-2 in situ hybridization immunohistochemical staining after centrifugalization and washing in the bcl-2 control and bcl-2 experimental group.
     实验第20天,所有小鼠全部处死,取小鼠一侧股骨骨髓细胞,bcl-2对照组,bcl-2实验组离心洗涤后涂片做bcl-2原位杂交免疫组化染色。
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     All the mice were sacrificed after 18h.
     18小时后处死所有小鼠
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     ④After 7 days of administration of KA, all the mice were anesthetized, and their brains were harvested, then fixed and embedded.
     ④给药7d后,麻醉所有小鼠,取脑,固定,包埋。
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  “所有小鼠”译为未确定词的双语例句
     Except the control group,rats in other groups received intragastric administration of 0.5 mL of Hp with the concentration of 1×1012 CFU/L,and repeated at each 12 hours for totally 3 times.
     除健康对照组外,所有小鼠经灌胃幽门螺杆菌液0.5mL/只(浓度1×1012CFU/L),每间隔12h重复1次,共3次。
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     All mice were injected with 18F-FLT or 18F-FDG through the tail veins. The biodistribution of 18F-FLT and 18F-FDG in tumor tissue was measured with well-gamma detector 60 min after injection; the PET imaging of mice was performed.
     所有小鼠经尾静脉注入18F-FLT或18F-FDG,注药后60min用井型探测仪测量小鼠18F-FLT和18F-FDG的生物分布,并行PET显像。
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     METHODS: ① Eighty-five anesthetized mice were slowly administrated with 7.69 g/L KA by micropipette which was connected to nose of mouse at the dose of 48 mg/kg.
     方法:①所有小鼠经麻醉后,按48mg/kg剂量将7.69g/L海人藻酸滴入85只小鼠双侧鼻孔中。
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     Methods 160 mice were divided into 4 groups of 40 each. Group A was used as control whereas group B, C and D were experimental groups. Identical skin incision and suturing were executed over the backs of mice on day 0, 7 and 14 after the chemotherapy.
     方法 实验小鼠设 4组 ,每组 40只 ,A组为对照组 ,B、C、D组为化疗后不同时间的实验组 ,给予VCA联合化疗 ,分别于化疗后 0d、7d和 14d在背部做相同切口并缝合 ,所有小鼠术后 7d处死 ,愈合伤口做拉力实验。
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     Results In the treated group, the HBV DNA electrophoresis band disappeared in 20% of the mice after 1 week of 3TC oral administration, 70% after 2 weeks treatment and 100% after 3 weeks treatment, 1 week after termination of 3TC administration, 78% in the 3TC treatment group were retested, and HBV DNA electrophoresis band reappeared.
     结果 实验组用拉米夫定 1周后 2 0 %小鼠血清HBVDNA电泳带消失 ,2周后 ,70 %HBVDNA电泳带消失 ,3周后 ,所有小鼠血清HBVDNA电泳带消失 ,停药 1周后 ,再次检测血清HBVDNA ,78%小鼠血清HBVDNA电泳带又出现。
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  相似匹配句对
     All mice were killed to do experiment.
     处死所有小鼠进行试验。
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     All the mice were killed at the end of the 6th week.
     6周末,将所有小鼠处死。
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     than that in WT mice.
     通小鼠
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     Results: All C.
     结果 :所有C .
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     V(I) for all f.
     V(I)对所有f.
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  all the mice
The exact test for differentiation, however, did not confirm the affiliation of all the mice examined to one population: χ2 = 1446, d.f.
      
Serum samples were collected from all the mice before and after vaccination and at the end of the experiment, and used for antibody detection.
      
All the mice were killed at the age of 9 months and the immunologic function was examined.
      
The highest mortality occurred when all the mice in the aggregate received amphetamine (10 A), whereas, the lowest mortality occurred in mice (1 A) isolated after amphetamine injection.
      
All the mice consumed more food at night than in the day-time, though this nocturnal peak was markedly reduced in old and mature animals.
      
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Albino mice are animals commonly used for experimental studies on malaria. It is very necessary to find a strain of mice most susceptible to the P. yoelii-A. stephensi system. Thus, experimental studies were carried out on 9 inbred strains of mice (SMMC/A, SMMC/B, SMMC/C, SMMC/D, C57BL, C3H, 615, SMMC/C×615, Jin-bai N0.1)and one outbred strain (Kuming strain) by means of both sporozoite-and blood-induced infections. The results obtained are summarized as follows.(1) Although all of the 10 strains became patent...

Albino mice are animals commonly used for experimental studies on malaria. It is very necessary to find a strain of mice most susceptible to the P. yoelii-A. stephensi system. Thus, experimental studies were carried out on 9 inbred strains of mice (SMMC/A, SMMC/B, SMMC/C, SMMC/D, C57BL, C3H, 615, SMMC/C×615, Jin-bai N0.1)and one outbred strain (Kuming strain) by means of both sporozoite-and blood-induced infections. The results obtained are summarized as follows.(1) Although all of the 10 strains became patent after blood inoculation, producing an infection rate of 100%, yet there exists a very significant difference in susceptibility to sporozoite-induced infection between different strains of the test mice. Six strains of them including SMMC/C were found most susceptible to infection, reaching 100% patency. (2) As compared with others, the SMMC/C strain had the shortest prepatent period (4.22±0.43 days) with the least difference in the time of first appearance of the parasites in the circulating blood amongst individuals of this strain. (3) When the anopheline mosquitoes fed on each of the 10 strains, SMMC/C strain was found most infective to the vector with the gland infection rate of 73.20±5.9%. From all the results obtained, with A. stephensi as its transmitter, out of the 10 strains the SMMC/C is considered the most susceptible and suitable animal model for experimental studies on rodent malariaThe observations made on the SMMC/C mice showed the following results. (1) Five thousand sporozoites per mouse intraporitoneally inoculated were required to ensure an infection rate of 100%. (2) More than 90% of the mice became infected following intraporitoneal inoculation of the sporozoites which were preserved in the glucose normal saline mixed with albino rat serum (1:1 in ratio) either at 3-5° or at 23-25° up to 24 hrs after dissection from the mosquitose. (3) Ambient temperature of 18-20℃ was most favourable to development of the parasite in the mice. (4) Young mice were most susceptible to the sporozoite-induced infection, the adult being second to them.All the experimental results obtained are discussed.

小鼠为疟疾实验研究最常用的动物。寻求出小鼠对约氏疟原虫易感的品系(株),对疟疾实验研究是非常需要的。本文报告9株近交小鼠及一株远交小鼠对约氏疟原虫(Plasmodium yoelii yoclii)—斯氏按蚊(Anopheles stephensi)系统的敏感性的实验结果,经蚊传和血传试验表明:(1)输血转种所有小鼠均极敏感,而子孢子感染则各鼠株之间有差异,SMMC/C株等6个鼠株最为敏感,阳性率为100%;(2)子孢子感染的原虫血症出现时间,以SMMC/C株最早,並且出现时间比较一致;(3)斯氏按蚊对各阳性鼠株的易感性以SMMC/C株的腺感染率最高(73.20±59.2%)。因而,认为小鼠SMMC/C株—斯氏按蚊系统作为鼠疟实验动物模型较为适宜。另外,本文还报告,在约氏疟原虫感染SMMC/C鼠株实验中发现(1)每鼠接种子孢子5000个可使全部鼠感染上;(2)子孢子在鼠血清葡萄糖生理盐水在3~5 C或23~25 C下体外保存24小时后,90%以上的小鼠被感染上;(3)环境温度18~20 C对小鼠感染疟原虫发育最适宜;(4)幼鼠对子孢子感染最敏感,成年鼠次之。 对本试验结果进行了讨论。

As reported by us previously, FA pretreated grafts can prolong the mean survival time (MST) of both allo-and xenogenic skin grafts. On the basis that the 2nd set graft will be rejected earlier than the 1st one, the present 2 experiments were designed with the intension of exploring the role of FA in prolonging the survival time of skin grafts.Exp. Ⅰ: In the 1st set grafting, mice were divided into 2 groups, namely, non-pretreated skin grafting (control group) and FA-treated skin grafting(FA group). As soon as...

As reported by us previously, FA pretreated grafts can prolong the mean survival time (MST) of both allo-and xenogenic skin grafts. On the basis that the 2nd set graft will be rejected earlier than the 1st one, the present 2 experiments were designed with the intension of exploring the role of FA in prolonging the survival time of skin grafts.Exp. Ⅰ: In the 1st set grafting, mice were divided into 2 groups, namely, non-pretreated skin grafting (control group) and FA-treated skin grafting(FA group). As soon as 2/3 of the control grafts were rejected, the still living grafts of the FA group were peeled off. Twenty days after the transplantation of the 1st set, the 2nd grafting were performed with non-pretreated skin on both groups of animals. No acceleration of rejection of FA-pretreated allografts was observed, and its MST was as long as that of grafting of control group in the 1st set. It denotes that FA has shown some effect in retarding the development of rejection response of the host. But the result is different in xenografting. There was accelerated rejection in both control and FA groups, indicating that in the 1st set grafting the host has also been sensitized by FA treated grafts, although the grafts themselves were protected by FA and showed no sign of rejection before they were peeled off.Exp. Ⅱ: In the 1st set grafting, all mice were grafted with non-pretreated skin to sensitize the hosts. Twenty days later, non-pretreated or FA treated skin grafts were transplanted. There was not only no accelerated rejection but also prolongation of MST of treated grafts in either allo-or xenografts. It suggests that FA protects the treated grafts against the rejective of the already sensitized hosts.Therefore, the preliminary impression of the role of FA in prolonging allo-or xenografts is mainly a temporary local protective effect against the host's rejection reaction. In allografting, in addition to local protection, there seems to be some effect of FA in retarding the establishment of immune response of the host.

实验一:在第1次植皮时,受皮小鼠分两组,对照组植以新鲜皮片,氟氢松醋酸酯(FA)组植FA处理的皮片。当2/3对照组皮片排斥时,将仍生长良好的FA组皮片撕去。于第1次植皮后20天给予第2次植皮,两组均植以新鲜皮片。在同种移植,FA组的第2次所植皮片未见加速排斥,其平均存活时间与对照组的第1次植皮相近,说明FA对宿主排斥反应的建立有一定的推迟作用。但在异种移植则不同,对照和FA组的第2次所植皮片均呈现加速排斥,说明在第1次植皮时,经FA处理的皮片在被撕去前已使宿主致敏,而皮片本身由于FA的保护作用仍生长良好,无被排斥的征兆。实验二:在第1次植皮时,所有小鼠均植以新鲜皮片,使宿主致敏。20天后分为两组分别植以新鲜皮片及经FA处理皮片。不论在同种或异种移植,经FA处理的皮片不仅未见加速排斥,且其存活期还有所延长。说明FA可以保护被处理皮片对抗已被致敏宿主的排斥反应。总之,关于FA的作用机理,可能是暂时性的局部保护作用,以对抗宿主的排斥。而在同种移植,还有一定的推迟宿主免疫反应建立的作用。

After mouse ascitic carcinoma cells (U14) 2×106 were inoculated subcu-taneously into right footpads of inbred 615-strain mice, the subcutaneous primary tumor growth was resected by right hind leg amputation in 6-10 mice 1,2,3,5,7,9 and 11 days after inoculation respectively. Another 9 mice without hind leg amputation served as controls. All animals were sacrificed on the 26th day. Results showed that tumor invasion was not apparent on the 1st day after transplantation (grade 0). Slight tumor invasion was noticed...

After mouse ascitic carcinoma cells (U14) 2×106 were inoculated subcu-taneously into right footpads of inbred 615-strain mice, the subcutaneous primary tumor growth was resected by right hind leg amputation in 6-10 mice 1,2,3,5,7,9 and 11 days after inoculation respectively. Another 9 mice without hind leg amputation served as controls. All animals were sacrificed on the 26th day. Results showed that tumor invasion was not apparent on the 1st day after transplantation (grade 0). Slight tumor invasion was noticed on the 2nd day (grade Ⅰ); grades Ⅱ -Ⅲ invasion were noticed on the 3rd-5th days; and grades Ⅲ-Ⅳ invasion on the 7-Ⅰth days. Lymphatic metastases appeared on the 7th day after transplantation, both lymphatic metastasis and lung metastases occurred in 80% of the mice Ⅰ days after inoculation. The results indicate a close relationship between tumor cell invasion and metastasis, i.e., tumor metastasis was noticed on the 7th day as tumor invasion reached grade Ⅲ. Also, lymphatic metastasis was noticed 2 days earlier than lung metastasis. Results of this experiment provide very useful data for studies on the treatment of tumor invasion and metastasis and the relationship between lymphatic and hematogenic metastasis.

将小鼠子宫颈癌14号瘤细胞移植于小鼠爪垫皮下,在不同间隔时间切除一批荷瘤动物的后下肢(含原发瘤),所有小鼠均于瘤细胞接种后26d处死。观察肿瘤在局部的侵袭程度及肺,淋巴结出现转移的时间及程度.结果表明,瘤细胞在移植后2d开始侵袭,3和5d侵袭达Ⅱ~Ⅲ级,7、9和11d侵袭达Ⅲ~Ⅳ级。肿瘤移植后7d出现淋巴结转移,9d发生肺转移。11d肺和淋巴结转移占80%。可见局部肿瘤达到Ⅲ级侵袭方出现转移。

 
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