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凋亡
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  apoptosis (
     Single factor analysis showed that apoptosis (χ~2=6.77,P<0.01), mutated p53 (χ~2=6.56,P<0.05), the metastasis of lymph node (χ~2=16.31,P<0.01), and TNM stage (χ~2=15.86,P<0.01)affected the prognosis of lung cancer patients;
     单因素分析肺癌患者预后的影响因素有凋亡(χ2=6·77,P<0·01)、突变型p53(χ2=6·56,P<0·05)、淋巴结转移(χ2=16·31,P<0·01)和TNM分期(χ2=15·86,P<0·01);
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     Single factor analysis showed that apoptosis (χ2=8.31,P=0.003 9), bcl-2(χ2=4.41, P=0.035 7), the metastasis of lymph node (χ2=19.34,P= 0.000 1) and TNM stage (χ2=18.54,P=0.000 1) affected the prognosis of lung cancer patients.
     单因素分析显示,肺癌患者预后的影响因素有凋亡(χ2=8·31,P=0·0039)、bcl-2(χ2=4·41,P=0·0357)、淋巴结转移(χ2=19·34,P=0·0001)和TNM分期(χ2=18·54,P=0·0001);
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     Results:Compared to the spontaneous apoptosis(55±10)% of neutrophils cultared in vitro for 24 h,the cell apoptosis of neutrophils cultured with Mtb-Ag(1.125 mg/ml) decreased(31±3)%(P<0.01);
     结果:与中性粒细胞体外培养24 h后自发凋亡(55±10)%相比,加入Mtb-Ag(1.125 mg/ml)后,中性粒细胞自发凋亡率(31±3)%明显降低(P<0.01);
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     The apoptotic rate of group A was 45.0±0.3%, but neither group B or C showed obvious apoptosis (P <0.01).
     A组细胞凋亡率45.0±0.3%,B,C组均未发生明显凋亡(P<0.01).
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     After exposure to desipramine ( 20 μmol·L -1 ) for 24 h, C6 g l ioma cells would undergo the early cell apoptosis (13.1 %) which was not a ffected by fumonisin B1 (10 μmol·L -1 ).
     地昔帕明(20μmol·L-1)可诱导C6细胞发生早期凋亡(13.1%),而FB1(10μmol·L-1)预处理对凋亡发生率无明显影响。
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  “凋亡(”译为未确定词的双语例句
     ②Apoptosis of L9981 was remarkably induced by MSA at the concentration of 2.5 μmol/L (P<0.05).
     ②MSA浓度在2.5μmol/L时可诱导L9981细胞株进入凋亡(P<0.05)。
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     Apoptosis was programmed cell death process.
     凋亡(apoptosis,AP)是细胞的程序性死亡(programmed cell death,PCD)过程。
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     Moreover, the percentage of hepatic cell oncosis was higher than that of apoptosis in BDL group (25.41% ± 2.18% vs 2.79% ± 1.43%, P < 0.05).
     BDL组胀亡细胞百分比显著高于凋亡(25.41%±2.18% vs 2.79%±1.43%,P<0.05).
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     Both DHEA and DHEA plus E2 at physiological concentrations, had no effects on apoptosis of PBMC from healthy donors(P >0.05),but significantly inhibited that of SLE patients(P< 0.05);
     生理浓度的DHEA及DHEA+E2对健康献血员PBMC凋亡无影响(P>0.05),但可显著抑制SLE患者PBMC凋亡(P<0.05);
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     Eos apoptosis in AM- treated group(15±5, 14±4) was remarkably higher than that in asthmatic group( P<0.01);
     用AM 24h后不同密度Eos数量 ( 36±14, 33±8 )均明显低于哮喘组 (P<0 01, 0 05),AM组Eos凋亡 ( 15±5, 14±4 )明显高于哮喘组(P<0 01);
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  相似匹配句对
     Apoptosis of primordial germ cells
     原始生殖细胞的凋亡
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     decreasing chondrocyte apoptosis.
     抑制软骨细胞凋亡
短句来源
     (5) apoptosis.
     (5 )凋亡精子。
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     APOPTOSIS IN YEAST
     酵母菌凋亡(英文)
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  apoptosis (
Prodigiosin also could induce apoptosis of pancreatic cancer cells at low concentration and results in the fragmentation pattern of DNA.
      
All these results demonstrate that prodigiosin can obviously inhibit the proliferation of pancreatic cancer cells H8898 by arresting the cell cycle and inducing apoptosis.
      
Detection of the apoptosis of Jurkat cell using an electrorotation chip
      
The apoptosis of cells is one of the fields that attract increasing attention in biology today.
      
Usually, the cells are treated with chemicals when detecting apoptosis.
      
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At various stages of life cycle of cells,e. g. proliferation,differentiation and death,occurrence of DNA strand breaks(DSB)is a common event.For several years,we have been investigating DSB in various tissues at different states of differentiation by in situ nick translation (INT),leading to a finding that there are two tpyes of DSB,one is readily detected by INT,and the other is difficult.INT was performed under the conditions in that,in normal small intestine,the nuclei of terminally differentiated epithelial...

At various stages of life cycle of cells,e. g. proliferation,differentiation and death,occurrence of DNA strand breaks(DSB)is a common event.For several years,we have been investigating DSB in various tissues at different states of differentiation by in situ nick translation (INT),leading to a finding that there are two tpyes of DSB,one is readily detected by INT,and the other is difficult.INT was performed under the conditions in that,in normal small intestine,the nuclei of terminally differentiated epithelial cells at the tip of villi is stained,whereas the nuclei of S phase epithelial cells in the crypt remain unstained and the latter become stainable only with proteinase K treatment.Specifically, frozen sections of the tissues were fixed with ethanol/acetic acid and INT was carried out at 37℃ for 3 hrs with 20μmol/L biotin-11-dUTP and 200IU /ml DNA polymerase 1,as described previously.In this study,we also investigated which type the DSB associated with apoptosis and necrosis belong to,As models of apoptosis and necrosis,rat thymus with an i.p.injection of hydrocortisone(10 mg/100 g BW) and rat livers dama ged with CCl4(100 μl/100 g BW) were used,respectively.It was found that the nuclei of steroidtreated thymocytes in the cortex were stained only when treated with proteinase K, while the hepatocyte nuclei treated with CCl4 were stained without protease digestion, These results indicate that the environment and/or nature of DSB in apoptosis differ from that of necrosis and INT is a convenient molecular histochemical tool to discriminate both types of cell death.

用原位缺口翻译法(INT)比较了细胞凋亡和坏死所伴随的DNA断裂(DSB)类型。INT实验条件为:取大鼠小肠制备冰冻切片,乙醇/醋酸固定,加20μmol/Lbiotin-11-dUTP、0.2IU/LDNA聚合酶Ⅰ,于37℃中孵育3h。正常大鼠小肠绒毛顶端上皮细胞可迅速被染色;而位于肠绒毛基底部的S期上皮细胞则不着色,仅在用蛋白酶K处理后才着色。细胞凋亡标本取自皮下注射氢化可的松(10mg/100g体重)的大鼠胸腺;细胞坏死用CCl4(100μl/100g体重)处理的大鼠肝脏。结果表明,经激素处理的胸腺皮质细胞核只有在蛋白酶K处理后才被染色,而CCl4处理后的肝细胞核不必用蛋白酶K消化就能直接显色。说明细胞凋亡的DSB显色特性不同于细胞坏死。

poptosis.programmed cell death.is a natu-ral form of cell death characterized by activeParticipated of a cell in the process leading toits own decrepit and death. Recently.studiessuggested that apoptosis is a result from a setof discrete cellular events that are regulated bya cascade gene expression.Oncogenes and tu-mor suppressor genes are involved in this regu-lation. Apoptosis is closely related to cancer.Failure and bolckage of apoptosis in tumorcells could therefore be the fundamental impor-tance in contributing...

poptosis.programmed cell death.is a natu-ral form of cell death characterized by activeParticipated of a cell in the process leading toits own decrepit and death. Recently.studiessuggested that apoptosis is a result from a setof discrete cellular events that are regulated bya cascade gene expression.Oncogenes and tu-mor suppressor genes are involved in this regu-lation. Apoptosis is closely related to cancer.Failure and bolckage of apoptosis in tumorcells could therefore be the fundamental impor-tance in contributing not only to the evasion ofphysiological countrols on cell numbers.butalso to the resistance both to natural defensesand to clinical therapy.

细胞凋亡是细胞衰老、死亡过程的主要形式。最近研究发现有多种癌基因与抑癌基因参与细胞凋亡过程。因此目前认为癌基因与抑癌基因不仅控制细胞增殖,分化,而且调节细胞凋亡。细胞凋亡受阻或缺陷可能是肿瘤发生的基础之一。

e apphed more sensitive

采用高敏感多重PAP免疫细胞化学技术,研究抗细胞凋亡基因bcl-2在淋巴结何杰金氏病中的表达与分布。结果表明,21例中有7例(33%)可检出bcl-2蛋白阳性的Reed-Sternberg(R-S)细胞;其中2例(混合细胞型)尚含大量反应性淋巴滤泡,其生发中心也呈阳性反心。相反4例作为阳性对照的炎性淋巴滤泡增生中,bcl-2蛋白主要分布于富含长寿命(long-lived)B细胞的套区(mantlezone),而生发中心则均为阴性。结果提示,bcl-2基因高表达介导的细胞凋亡障碍可能与R-S细胞发生有关。

 
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