助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   基因治疗tmj 的翻译结果: 查询用时:0.017秒
图标索引 在分类学科中查询
所有学科
更多类别查询

图标索引 历史查询
 

基因治疗tmj
相关语句
  gene transfer method
     PURPOSE:This study is to confirm that soluble interleukin-1receptor(sIL-1RI)gene can be delivered to articular chondrocytes and synovium in goat temporomandibular joint(TMJ)using direct in vivo gene transfer method by liposome.
     目的:观察脂质体携带的可溶性白介素-1受体(sIL-1RI)基因重组质粒注入山羊颞下颌关节(TMJ)上腔后,在TMJ髁突软骨及滑膜组织中的表达,以及在全身其他重要器官组织中的表达,为施行基因治疗TMJ骨关节病(OA)奠定基础。
短句来源
  相似匹配句对
     Gene Therapy
     基因治疗
短句来源
     Gene Therapy in Heart Failure
     心力衰竭的基因治疗
短句来源
     4 new genes were obtained.
     U基因
短句来源
     A.N. Goss:Toward an international consensus on temporomandibular joint surgery
     TMJ手术的国际共识
短句来源
     Result: The result showed the asymmetric TMJ in children.
     结果 :儿童左右TMJ间隙不对称。
短句来源
查询“基因治疗tmj”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。
  gene transfer method
This novel gene delivery system provided a safer, more simple and efficient gene transfer method for primary hepatocytes, and showed prospecting application in hepatic gene therapy.
      
Method - A nonviral gene transfer method for transfecting multipotent adult progenitor cells (MAPC)
      
We developed an efficient gene transfer method mediated by Agrobacterium tumefaciens for introgression of new rice for Africa (NERICA) cultivars, which are derivatives of interspecific hybrids between Oryza glaberrima Steud.
      
Since the handling stress of stripping gametes from female sliver sea bream brood fish could cause severe mortality, an alternative gene transfer method would be highly desirable.
      
The relative strengths of several commonly used viral promoters in primary cultures of rat mammary epithelial cells were studied using a particle bombardment gene transfer method.
      
更多          


PURPOSE:This study is to confirm that soluble interleukin-1receptor(sIL-1RI)gene can be delivered to articular chondrocytes and synovium in goat temporomandibular joint(TMJ)using direct in vivo gene transfer method by liposome.METHODS:Recombiant liposomes vector carrying sIL-1RI gene was injected into the upper joint cavities of both TMJs of six male goats.At2and4weeks after injection,6joints were dissected respectively and the expression of delivered sIL-1RI gene in synovium and articular cartilage of goat...

PURPOSE:This study is to confirm that soluble interleukin-1receptor(sIL-1RI)gene can be delivered to articular chondrocytes and synovium in goat temporomandibular joint(TMJ)using direct in vivo gene transfer method by liposome.METHODS:Recombiant liposomes vector carrying sIL-1RI gene was injected into the upper joint cavities of both TMJs of six male goats.At2and4weeks after injection,6joints were dissected respectively and the expression of delivered sIL-1RI gene in synovium and articular cartilage of goat TMJ was examined immunohiso-chemically.Meanwhile,the expression of sIL-1RI gene in liver,heart,kidney,and brain of goat was examined immunohisochemically.The protein expression products in TMJ synovial fluid samples were detected by ELISA and statistical significance was assessed using q test.RESULTS:Clear expression of sIL-1RI gene was observed in the synovial membrane,articular cartilage,and subchondral bone tissue of the goat TMJ,while no expression was detected in goat liver,heart,kidney,and brain.The protein expression products could be detected in synovial fluid samples by ELISA,and the level of expression in experimental group were significantly higher than that in the control groups(P<0.05). CONCLUSION:Direct genesurface and articular cartilage of the goat TMJ using the liposomes vector carrying sIL-1RI gene is feasible as an effective in vivo method.

目的:观察脂质体携带的可溶性白介素-1受体(sIL-1RI)基因重组质粒注入山羊颞下颌关节(TMJ)上腔后,在TMJ髁突软骨及滑膜组织中的表达,以及在全身其他重要器官组织中的表达,为施行基因治疗TMJ骨关节病(OA)奠定基础。方法:将脂质体携带的sIL-1RI基因重组质粒分别注入6只山羊TMJ的关节上腔。注射后第2、4周,分别处死3只动物。抽取TMJ关节滑液,用ELISA法检测关节滑液中的蛋白表达量。采用q检验,对实验数据进行方差分析和均数间的两两比较。切取完整关节标本以及肝脏、心脏、肾脏和脑组织,免疫组化法检测重组质粒在这些脏器组织中的表达情况。结果:重组质粒pcDNA3/sIL-1RI在山羊TMJ的滑膜细胞、软骨细胞及软骨下组织均有表达。ELISA方法检测结果显示,实验组表达量明显高于对照组(P<0.05)。在山羊肝脏、心脏、肾脏和脑等全身重要组织器官中未见表达。结论:脂质体携带的重组质粒pcDNA3/sIL-1RI,可在山羊TMJ有效地表达,关节外组织未见表达,因此是安全、可行的。

 
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关基因治疗tmj的内容
在知识搜索中查有关基因治疗tmj的内容
在数字搜索中查有关基因治疗tmj的内容
在概念知识元中查有关基因治疗tmj的内容
在学术趋势中查有关基因治疗tmj的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社