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  h-h
     n algorithm was developed to calculate protein solution conforniations from 2DNOESY intensities. With the complete relaxation matrix analysis programMARDIGRAS the H-H atom distance constraints are evaluated. With the distaneegeometry program DISMAN the three dimensional structures of proteins are calculatedwhich are refined further by the restrained molecular dynamics program r-MD andthe energy rninimization program r-EM.
     建立由2DNOESY诺峰强度计算蛋白质溶液构象的实用方法,先用完整弛豫矩阵分析方法程序计算H-H原子间距约束,然后用距离几何算法程序计算出三锥空间结构,再用有约束的分子动力学算法程序结合能量优化程序精化结构,并模拟出该结构的NOESY诺峰强度与实验NOESY谱峰强度对比,经多次迭代计算与精化得到合理稳定的蛋白质构象。
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     Using a quasiclassical trajectory method, the results including vibration rotation coupled excitations and a aligned propensity of the rotational excitations for H-H 2O colliding system were presented, which are agreement essentially with the recent experiments.
     利用半经典微扰理论计算了在H-H2O的非弹性碰撞中的H2O分子的转动、振动激发,并将计算结果与实验结果进行比较。
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     These features are obtained by long-term physiological experiments, or by H-H equation with computer simuiation which we carried out The neuron models, which have these nine neuron properties, are not convenient for mathematical analysis.
     这些特性是从长期的生理实验中获得的,也可以由H-H方程经计算机模拟获得[1],我们作了这些模拟。 由这九个特性构成的神经元模型不便于作统一的数学分析。
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     The resuItsshowed that the subunit structure of fibroin expresses two different types : Bombyx moriand Bombyx mandarina are H-L type , Antheraea pernyi、Antheraea yamamai、Philosamia cynthia Philosamia cynthia ricini are H-H type , The six silkworms havespecies specificility in amino acid composition of their fibroin.
     结果表明,丝心蛋白亚基的组成家蚕、野桑蚕表现为H-L型,天蚕、柞蚕、樗蚕、蓖麻蚕为H-H型。
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     The molecular mechanics calculation started with the sugar-rings inchair-form,CH_3 used instead of R_F group.Conformer 1 is convinced as the stableone in polar solvents by energy minimization. Good agreement is observed betweenthe calculated and expermental H-H distances of conformer 1.
     分子力学计算中,根据能量最低原则,算得φ_(oc1'oc4)角为89.4°,中φ_(oc6c5o)(及φ_(oc6'c5'o)角)角为-177.2°时的构象最为稳定,从这一稳定构象读得的相应8对H-H间的距离与NOESY的结果符合。
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     SEMICLASSICAL PERTURBATION THEORY CALCULA TIONS ON THE INELASTIC COLLSIONS OF H AND H 2O ROTATIONAL AND VIBRATIONAL EXCITATIONS OF H 2O
     利用半经典微扰理论研究H-H_2O的非弹性碰撞—H_2O的转动、振动激发
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     By using the double tracer, drawing 14 C sucrose into phloem of cotton stem and 3H water into xylem of cotton stem were researched in this experiment. The photosynthate transports in phloem by liquid form and the water of the liquid mainly comes from the xylem.
     带库棉花果枝的韧皮部与木质部基部不分离,通过韧皮部引入14C-蔗糖溶液(5%)、木质部引入3H-H2O的双标记技术所作的研究表明,同化物在韧皮部中以液流形式运输,液流中的水主要来源于木质部,运输一定量的14C-同化物需一定量的3H-H2O。
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     The result shows that the photosynthate and the water from xylem transportation in phloem are closely interrelated, and the quantitive relationship is Y=0 10773X .
     由LS-9800液闪仪测出韧皮部中14C-同化物的放射性计数和对应CaO中3H-H2O的放射性计数,由此计算出韧皮部运输的同化物的量(Y)与伴随运移水分的量(X)之间的定量关系为:Y=0.10773X。
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     Four typer of solid superacid and their preparation methods have been discussed here, which are: (1 )sulfated metal oxides, (2 ) Cs2.5H0.5W12O40 salt, (3) AlCl3 - sulfonic acid resin complexes, (4 ) perfluorinated ion exchange polymer (Nafion - H PEIEP).
     目前研究较多的固体超强酸有负载硫酸超强酸、Cs2.5盐、AlCl3/PS-DVB磺酸树脂体系和全氟磺酸树脂(Nafion-H-H PEIEP)四种。
短句来源
     To P -lactamderivatives 3a and 4a,we studied their Nuclear Overhauser Effect(NOE) differenceexperiments, and their conformation was testified together with analysis of thevicinal proton-proton coupling constants.
     对于β-内酚胺衍生物3a和4a,通过测试NOE差谱,并结合H-H偶合常数证实了产物的构象。
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  hh
This work for the first time compares results obtained with studies of parametric robustness of the Hh-and Dpp/BMP signal cascades responsible for morphogenesis and molecular evolution of the Hh-and Dpp/BMP cascade genes.
      
Special attention is paid to events of the molecular evolution of the Hh-and Dpp/BMP cascade genes that matched with the emergence of the major taxonomic types and classes of Bilateria.
      
The review considers the main regularities and molecular mechanisms of the process, as well as the functions of Hint domains in other protein families (Hh proteins, bacterial BIL domains, etc.).
      
Several reproductive parameters were studied in males homozygous (hh) or heterozygous (Hh) for thehooded mutation as compared with completely pigmented wild-type males (HH).
      
The proportion of sterile males in homogeneous matings of homozygotes hh was twice as high as in matings of heterozygotes.
      
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PaoTa bIa BbIoHeHa o pykoBocTBoM po. B. B. ooBa B oooeckoMHcTTyTe A. H. CCCP. ABTop BbIpaaeT yoky aoapHocTb a pykoBocTBooMob. B cTaTbe bIo apecTppoBaHHo 17 BoB, oTHocxc k 3 poaM (Ceratina,Neoceratina Allodape), 4 Hx BTc HoBbIM BaM: Ceratina (Ceratinidia)popovi, Ceratina (Ceratinidia) denticulata, Ceratina (Ceratinidia) laeviuscula Neocera-tina chinensis; 9 BoB BepBbIe ykabIBaTc B KTae. keMppbI bI copaHHbI B o-aaHoM KTae yacTHkaM kce. 1. Ceratina (Ceratinidia) popovi n. sp. (pc. 1--6) . Ha 7--8 MM. ooBa HeMHoo...

PaoTa bIa BbIoHeHa o pykoBocTBoM po. B. B. ooBa B oooeckoMHcTTyTe A. H. CCCP. ABTop BbIpaaeT yoky aoapHocTb a pykoBocTBooMob. B cTaTbe bIo apecTppoBaHHo 17 BoB, oTHocxc k 3 poaM (Ceratina,Neoceratina Allodape), 4 Hx BTc HoBbIM BaM: Ceratina (Ceratinidia)popovi, Ceratina (Ceratinidia) denticulata, Ceratina (Ceratinidia) laeviuscula Neocera-tina chinensis; 9 BoB BepBbIe ykabIBaTc B KTae. keMppbI bI copaHHbI B o-aaHoM KTae yacTHkaM kce. 1. Ceratina (Ceratinidia) popovi n. sp. (pc. 1--6) . Ha 7--8 MM. ooBa HeMHoo pe cBoe HbI, paBHa pHe py.Mey aHTeHHabHo Mko eTbIM pcyHkoM okoBo acT a MeeTccBbIe 15 Toek. epHbI c eTbIM pcyHkoM. . ooeH . Ha 6.5 MM. oee epHbI. aH kpa 7 TepTa aocTpe-HHbI, cepeHa aHeo kpa 7 cTepHTa c 3 epHbIM xTHopoBaHHbIM THaM. B ok k Ceratina (Ceratinidia) okinawana Mats. et Uch., Ho oTaeTcpoko ooBo, MeHbM paMepoM oee cTpoHbIM TeoM pyM pHa-kaM. 2. Ceratina (Ceratinidia) denticulata n. sp. (pc. 7--13) . Ha 9 MM. ooBa HeMHoo pe cBoe HbI. pko yko. MeyaHTeHHabHo Mko eTbIM pcyHkoM okoBo acT a MeTc oee 15 Toek. epHbI c eTbIM pcyHkoM. pyb 1 TepT pka epHbIe, 2--4 TepTbIc pepBaHHbIM eTbIM oocaM. . ooeH . Ha 7.5--8 MM. Okpacka Tea epHee. Ⅶ TepT c MaeHbkMyoM, cepeHa aHeo kpa Ⅶ cTepHTa c 4 epHbIM xTHopoBaHHbIM T-HaM. B ok k Ceratina (Ceratinidia) popovi。Wu, Ho oTaeTc epHo pybepBbIM TepToM pka pepBaHHbIM eTbIM oocaM Ha Ⅱ Ⅲ Tep-Tax pka, Ⅶ TepToM caMa pyM pHakaM. 3. Ceratina (Ceratinidia) laeviuscula n. sp. (pc. 14) . Ha 7--8 MM. ooBa pe cBoe pHbI py. o oT a-koe. HaHk B pekx papocaHHbIx Tokax. Mey aHTeHHabHo MkoeTbIM pcyHkoM okoBo acT a HepeBbIaeT 15 Toek. yHkTpoBka Tep-ToB o cepeHe papocaHHbIe, a o kpaM ye. epHbI c eTbIM pcyHkoM. B ok k Ceratina (Ceratinidia) popovi Wu, Ho oTaeTc oee akMoM pyM pHakaM. 4. Neoceratina chinensis n. sp. (pc. 15--22) . Ha 4 MM. ooBa kBapaTHa, HH ooBHa a BbIyka. YckHHbIe, oxoT o Tka. e opoHTabHo oHbI poMeyToHoo ceMeHTa.pko okpyoe, Ⅶ TepT c TpeyobHo opo cbHo BbITHeT BH. ooBa cpeHecka ecTe. B ok k Neoceratina australians Perkin, Ho oTaeTc epHbIM TeoM (eeeHoBaToo oTTeHka), pyo yHkTpoBko cpeHecHk, Tko pyMpHakaM.

中、苏两国生物学工作者于1955—1957年间在云南及四川两省所采集的膜翅目蜜蜂总科Ceratinini族的17个种,分属于Ceratina、Neoceratina 及Allodape 3属。文中共记述了4个新种,另有9个种均为我国新记录。 此项工作系在苏联科学院动物研究所故通讯院士波波夫(B.B.)教授指导下完成的。文中雄性生殖器原图均系波波夫教授亲缯。 所记种类的单个标本及新种的正模标本均保存于中国科学院动物研究所。

In this paper concepts of δ—neighborhood amplitude and two—dimensional ε—spline function are intraduced. The following smoothing formula is geven, i, e x,y)=1/hh' integral from -∞ to ∞ integral from -∞ to ∞ Ω_1((x-s)/h)Ω_1((y-t)/h')(s,t)dsdt for measured values f_i, j at equally spaced nodes, where (x,y)=sum from i=1 to M sum from j=1 to N f_(i,j)Ω_1((x-x_i)/Δx)Ω_1((y-y_j)/Δy), Ω_1(x) is the first approximation function of δ—function. The following theorem is presented as a main result. Theorem: (x,y)...

In this paper concepts of δ—neighborhood amplitude and two—dimensional ε—spline function are intraduced. The following smoothing formula is geven, i, e x,y)=1/hh' integral from -∞ to ∞ integral from -∞ to ∞ Ω_1((x-s)/h)Ω_1((y-t)/h')(s,t)dsdt for measured values f_i, j at equally spaced nodes, where (x,y)=sum from i=1 to M sum from j=1 to N f_(i,j)Ω_1((x-x_i)/Δx)Ω_1((y-y_j)/Δy), Ω_1(x) is the first approximation function of δ—function. The following theorem is presented as a main result. Theorem: (x,y) is a second order ε—spline function of δ—neighgorhood amplitode at measured volues f_(i,j) on the close domain Ω: x_1≤x≤x_M, x_1≤y≤x_N, where ε=(p+q)/3-pq/9, p=h/Δx,q=h'/Δy,δ=(Δx~2+Δy~2)~(1/2) Appling to the plane numerical field is obtined the 9—points smoothing formule: _(i,j)=(1-p/3)(1-q/3)f_(i,j)+q/6(1-q/3)(f_(i-1,j)+f_(i+1,j)+q/6(1-p/3)(f_(i,j-1)+f_(i,j+1))+pq/36(f_(i-1,j-1)+f_(i-1,j+1)f_(i-1,j+1)+f_(i+1,j-1)+f_(i+1,j+1)).

本文引入了δ邻域差幅和二维δ—Spline函数的概念,给出下面的磨光公式,即对等间距节点(x_i,y_i)上的测值f_(i,j), 其中δ—函数的一次逼近。主要结果是下面的定理定理:(?)(x,y)是f_(i,j)在闭区域Q:x_1≤x≤x_M,y_1≤y≤y_N上的一个关于δ—差幅的2阶ε—Spline函数,其中ε=p+q/3=pq/9,p=h/△x,q=h'/△y,a=(△x~2+△y~2)~(1/2). 应用到平面数值场得到九点平滑公式(?)_(i,j)=(1-p/3)(1-q/3)f_(i,j)+p/6(1-q/3)(f_(i-1,j)+f_(i+1,j))+q/6(1-p/3)(f_(i,j-1)+f_(i,j+1))+pq/36(f_(i-1,j-1)+f_(i-1,j+1)+f_(i+1,j-1)+f_(i+1,j+1))。

Homoharringtonine (HH) is an effective antileukemic agent. We have studied its effeot on the volume ratio between nuoleolus and nucleus, as well as number of nucleolus per nucleus by the quantitative stereologic eleotronmioroscopio method. It has been demonstrated that HH at the dosage of 1.5 mg/kg could significantly stimulate the enlargement of nuoleolus volume by 2.8 times, and increased the number of nuoleolus by 1.7 times in comparison with the controls. It is suggested that such nucleolus stimulating...

Homoharringtonine (HH) is an effective antileukemic agent. We have studied its effeot on the volume ratio between nuoleolus and nucleus, as well as number of nucleolus per nucleus by the quantitative stereologic eleotronmioroscopio method. It has been demonstrated that HH at the dosage of 1.5 mg/kg could significantly stimulate the enlargement of nuoleolus volume by 2.8 times, and increased the number of nuoleolus by 1.7 times in comparison with the controls. It is suggested that such nucleolus stimulating action might be due to the inhibitory effect on ribosomal level of protein synthesis.It was also observed that HH at 1.5 mg/kg could induce a series of ultrastructural alteration in cardiac muscle cells of mice e. g. lysis of myofibrils, especially myosin, chromosome sparse distribution, pale of nuclear matrices, swelling of mitochondria and dilation of sarcoplasmio reticulum etc. When the dosage was increased to 3 mg/kg, obscurity and breakage of Z band, and damage of mitochondrial cristae were developed. For comparison, another cardiopathic antitumor agent Daunomycin was studied too, it could induce more serious ultrastructural abnormalities in cardiao muscle cells, such as vacuoles spreading everywhere in cardiac cytoplasm, breakage of mitochondria, appearance of 500~800 A filamentous struoture in capilaxies or interstitial of cells. Above-mentioned alterations induced by both drugs were similar to nonspecific deformations caused by cardiac anoxia.

高三尖杉酯碱(高杉)为治疗白血病有效药物。在超显微结构的研究中发现它除了产生一般性的细胞损伤外,还能选择性地对核仁产生刺激作用,见到核仁增大及增多。我们应用电子显微镜对肝细胞作定量观察,测定单位核体积所含核仁体积(Nu/N)的结果显示:用高杉1.5毫克/公斤腹腔注射20小时后,Nu/N显著增大,几乎为对照组肝细胞核仁的三倍,具体数值分别为0.14±0.02和0.05±0.01,统计学测验相差非常显著。同时实验组核仁数目也较对照肝细胞增加一倍左右,后者平均每核含有1.76个核仁,前者则为3.08,差别也显著。由于核仁是rRNA前体的合成部位,当核糖体蛋白质合成受抑制时,往往会经反馈作用引起核仁代偿性增大。因此,结合高三尖杉酯碱生化作用的研究,认为它可能是因为抑制了核糖体的蛋白质合成起始部位,从而导致核仁刺激作用。同时还定量分析了高三尖杉酯碱对核被表面积和厚度的影响,未见显著作用。在临床及动物实验中可见到,用高三尖杉酯碱治疗会发生心率不齐或心电图异常等变化。我们研究了它对小鼠心肌亚显微结构的变化,发现在注射1.5毫克/公斤后20小时小鼠心肌原纤维溶解,核质疏松、线粒体肿胀和肌浆网扩张等现象,如剂量增至3毫克/公斤...

高三尖杉酯碱(高杉)为治疗白血病有效药物。在超显微结构的研究中发现它除了产生一般性的细胞损伤外,还能选择性地对核仁产生刺激作用,见到核仁增大及增多。我们应用电子显微镜对肝细胞作定量观察,测定单位核体积所含核仁体积(Nu/N)的结果显示:用高杉1.5毫克/公斤腹腔注射20小时后,Nu/N显著增大,几乎为对照组肝细胞核仁的三倍,具体数值分别为0.14±0.02和0.05±0.01,统计学测验相差非常显著。同时实验组核仁数目也较对照肝细胞增加一倍左右,后者平均每核含有1.76个核仁,前者则为3.08,差别也显著。由于核仁是rRNA前体的合成部位,当核糖体蛋白质合成受抑制时,往往会经反馈作用引起核仁代偿性增大。因此,结合高三尖杉酯碱生化作用的研究,认为它可能是因为抑制了核糖体的蛋白质合成起始部位,从而导致核仁刺激作用。同时还定量分析了高三尖杉酯碱对核被表面积和厚度的影响,未见显著作用。在临床及动物实验中可见到,用高三尖杉酯碱治疗会发生心率不齐或心电图异常等变化。我们研究了它对小鼠心肌亚显微结构的变化,发现在注射1.5毫克/公斤后20小时小鼠心肌原纤维溶解,核质疏松、线粒体肿胀和肌浆网扩张等现象,如剂量增至3毫克/公斤时,Z带密度下降,局部断裂甚至消失,线粒体嵴也有些损伤。同时用另一对心脏有影响的抗癌药柔红霉素作比较,在等毒性剂量下(2.5与5毫克/公斤)所起的影响比高三尖杉酯碱严重得多。在高剂量组(5毫克/公斤)可产生空斑、肌纤维严重稀疏、线粒体破碎,Z带损伤,肌细胞广泛空泡化现象,毛细血管或细胞间质中出现纤维样物质等。这些变化可以说明临床和实验治疗所观察到的心肌毒性表现。

 
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