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羟基维生素d
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  hydroxyvitamin d
     Methods The rat model of renal calcium oxalate stones formation was induced by administering ethylene glycol and 1α Hydroxyvitamin D 3 [1α (OH)VitD 3] for 4 weeks.
     方法用乙二醇和 1α 羟基维生素D3 灌胃制作大鼠肾草酸钙结石模型。
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  “羟基维生素d”译为未确定词的双语例句
     Determination of 25-OH-D_3 concentration in human serum by HPLC
     HPLC法测定血中25-羟基维生素D_3的含量
短句来源
     RESULTS The method was linear over the range of 0.1 - 1.2 mg·L-1 for vitamin A and β-carotene, 20.0 - 240.0 μg·L-1 for vitamin DsJO. O- 120 μg·L-1 for vitamin 25-OH-D3 and 2.0-24.0 mg·L-1 for vitamin E.
     柱温:30℃。 结果维生素A和β-胡萝卜素在0.1-1.2 mg·L-1,25-羟基维生素D3在10.0-120.0 μg·L-1,维生素D3在20-240μg·L-1,维生素E在2.0-24.0 mg·L-1内线性良好;
短句来源
     The study was carried out to investigate the effects of 1,25 dihydroxyvitamin D 3 1, 25(OH) 2D 3 on cytoskeleton in rat osteoblast like cells (ROS 17/2.8) by immunofluorescent staining methods and on gene expression in human osteoblast like cells (OS 732) by a dot blot techique.
     用荧光免疫法研究了1,25双羟基维生素D3对大鼠成骨样细胞(ROS17/2.8)细胞骨架的影响和用斑点杂交技术研究了1,25(OH)2D3对人成骨样细胞(OS-732)基因表达的影响。
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     Evaluation of serum 25-hydroxy vitamin D level in children of Beijing
     北京市儿童血清25-羟基维生素D的水平探讨
短句来源
     Results: The ranges of calibration curves were 80 ~ 800 ng/ml (r =0. 9992).
     结果; 25-羟基维生素D_3在80-800 ng/ml浓度范围内线性良好(r=0.9992)。
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  相似匹配句对
     Comparison of Antihydroxyl Free Radical for Flavones and Vi tamin C
     黄酮及维生素C的抗羟基自由基的比较研究
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     Naturals vitamin E
     天然维生素E
短句来源
     ON THE SYNTHESIS OF METHIONINE METHYL SULFONIUM SALTS(VITAMIN U)
     维生素U的合成
短句来源
     Evaluation of serum 25-hydroxy vitamin D level in children of Beijing
     北京市儿童血清25-羟基维生素D的水平探讨
短句来源
     Mechanism for apoptosis of tumor cell induced by N-(4-hydroxyphenyl) retinamide
     N-(4-羟基苯基)维生素甲酰胺诱导肿瘤细胞凋亡的机制
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  hydroxyvitamin d
Since 1αOhase can locally convert 25-hydroxyvitamin D into 1α,25-dihydroxyvitamin D (1,25(OH)2D), an active metabolite of vitamin D, it is suggested that local production of 1,25(OH)2D by macrophages may promote atherosclerotic calcification.
      
Serum levels of calcium, PTH, 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D, urinary calcium excretion, blood pressure, and bone mineral density (BMD) were measured.
      
1,25-Dihydroxyvitamin D and 25-hydroxyvitamin D-mediated regulation of TRPV6 (a putative epithelial calcium channel) mRNA expres
      
Neuropsychological function in relation to serum parathyroid hormone and serum 25-hydroxyvitamin D levels
      
A low level of serum 25-hydroxyvitamin D was significantly associated with a high depression score.
      
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1 α 25-dihydroxy-vitamin D3(1α 25 (OH)2 D3)induced differentiation of human promyelocytic leukaemia cells ( HL-60 ) into mature myeloid cells in vitro. The ratio of nuclei to cytoplasma decreased; Their nucleoli reduced; Cells became irrgular and extended the pseudopods. 1 α 25 (OH ) 2 D3 caused significant increase of nitroblue tetrazolium ( NBT ) reduction and α-non-specific acid esterase (α-NAE ) and acid phosphatase (ACP ) activities. These data and morphological characteristics suggest that HL-60 cells...

1 α 25-dihydroxy-vitamin D3(1α 25 (OH)2 D3)induced differentiation of human promyelocytic leukaemia cells ( HL-60 ) into mature myeloid cells in vitro. The ratio of nuclei to cytoplasma decreased; Their nucleoli reduced; Cells became irrgular and extended the pseudopods. 1 α 25 (OH ) 2 D3 caused significant increase of nitroblue tetrazolium ( NBT ) reduction and α-non-specific acid esterase (α-NAE ) and acid phosphatase (ACP ) activities. These data and morphological characteristics suggest that HL-60 cells were conclusively identified as monocytes/macrophages. The histogram of DNA distribution ahylyzed by flow cytometry demonstrated G0 + G1 phase increased and S phase increased and S phase decreased remarkably after treatment with lα, 25 ( OH ) 2 D3 as compared with untreated cells.

1α,25二羟基维生素D_3在体外可诱导HL-60细胞向单核/巨噬样细胞发展。在形态上,核/质比例减少,核仁减少,细胞变得不规则并伸出伪足;在细胞化学方面,细胞对NBT还原能力增强,α萘酚醋酸酯酶和酸性磷酸酶阳性率明显增加,细胞周期的变化是:二倍体细胞明显增多,G_0+G_1期增加和S期减少。表明在1α,25(OH)_2D_3作用下,HL-60细胞向成熟分化,细胞DNA合成受抑制。

Serum concentration of 25-hydroxyvitamin D [25(OH)D_3] in 592 Beijing normal subjects (age: O-87 years), 256 cases maternal and cord blood and 361 patients with 20 different disorders (altogether1209 subjects) were determined by competitive protein binding assay. Decreased serum levels of 25(OH)D_3 compared with normal ware observed in patients with rickets, tetany, pneumonia infantilehepatitis, bone tumor, diabetes and renal disease and increased serum levels of 26 (OH) D_3 was inpatients with Vitamin D overdose...

Serum concentration of 25-hydroxyvitamin D [25(OH)D_3] in 592 Beijing normal subjects (age: O-87 years), 256 cases maternal and cord blood and 361 patients with 20 different disorders (altogether1209 subjects) were determined by competitive protein binding assay. Decreased serum levels of 25(OH)D_3 compared with normal ware observed in patients with rickets, tetany, pneumonia infantilehepatitis, bone tumor, diabetes and renal disease and increased serum levels of 26 (OH) D_3 was inpatients with Vitamin D overdose and fatty liver. Serum values of 1,25-dihydroxyvitamin D_3 [1,25(OH)_2D_3] were detected by radioreceptor assay in35 Beijing normal subjects, 28 cases of maternal and cord blood and 68 patients (131 in total). Serumvalues of 1,25(OH)_2D_3 was lower than normal in uremic, nephrotic syndrome and osteoporotic patientsand higher than normal in pregnant women. The results show that the variations of serum 25(OH)D_3 and 1,26(OH)_2D_3 are valuble indicatorsfor diagnosis, evaluating treatment and prognosis of metabolic bone disease.

本文采用竞争性蛋白结合法(CPBA)测定1209例受检者血清25羟基维生素D_3[25(OH)D_3],其中包括0~87岁健康人592例,孕妇与新生儿256例,患者361例(20个病种);并采用放射受体法测定131例受检查者血清1,25二羟基维生素D_3[1,25(OH)_2D_3],其中健康人35例,孕妇与新生儿28例,患者68例。结果表明,血清25(OH)D_3和 1,25(OH)_2D_3水平的变化对钙磷代谢失调及代谢性骨病的诊断、评价治疗和预后有重要参考意义。

The hydroxycolecalciferol preparations(including its analogs) and its clinical uses are introduced. The emphasis is put on the methods of preparing stabilized preparations. Its uses in cosmetics and dermatoses are briefly mentained.

简述羟基维生素D_3(活性V_(D3),包括相关物质)的临床应用及制剂。着重介绍了制备稳定的活性V_(D3)制剂的方法。并涉及其在透皮吸收制剂、化妆品方面的应用。

 
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