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诱导特异性
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  inducing specific
     The transfected DCs were capable of inducing specific killing of the target tumor cells, with the highest killing rate of (39.7±7.2)%.
     加病毒组DC可诱导特异性杀伤,最高杀伤率(39.7±7.2)%。
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     Objective To observe the changes of peripheral CD4+ T cells and CD8+ T cells between pre- and post-immunization of T cell vaccination, further to investigate the mechanism of T cell vaccination in inducing specific immune tolerance.
     目的 观察T细胞疫苗免疫前后外周血CD4~+和CD8~+T细胞的变化情况,探讨T细胞疫苗诱导特异性免疫耐受的作用及其机理。
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     CONCLUSION Fragement of 490 bp bcr abl gene immunization was capable of inducing specific CTL to kill the target cells that have expressed the bcr abl fusion gene.
     结论 位于融合位点两侧的 bcr- abl基因肌肉免疫小鼠能够诱导特异性 CTL ,杀伤 bcr- abl融合基因转染的靶细胞
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     The expression of IP-10 was assayed by Western blot and chemotaxis assay. The ability of stimulating syngeneic T cells and the effect of inducing specific kill activity of DC vaccine were detected.
     RT-PCR和Western blot检测转染DC IP-10的表达,测定转染DC上清对T细胞的趋化指数,检测DC瘤苗刺激T细胞的增殖以及诱导特异性CTL的杀伤作用。
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     DCs were pulsed with RM-1 prostate cancer cell lysate, and IL-12 was assay in the supernatant of sensitized DC culture fluid by enzyme linked immunosorbent assay(ELISA). The effect of inducing specific kill activity of DC vaccine was detected.
     RM-1前列腺癌细胞裂解物产物致敏DC,酶联免疫反应(ELISA)法检测致敏DC培养液上清IL-12,检测该瘤苗体外诱导特异性CTL的杀伤作用。
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  “诱导特异性”译为未确定词的双语例句
     Study of Specific Antitumor Immune Response Induced by pcDNA3.1/HSP70-MAGE-3 Fusion DNA Vaccine
     pcDNA3.1/HSP70-MAGE-3融合DNA疫苗诱导特异性抗肿瘤免疫应答的实验研究
短句来源
     Specific antitumor immune response induced by pcDNA3.1+/MAGE-3 DNA vaccine in mice
     pcDNA3.1+/MAGE-3 DNA疫苗诱导特异性抗肿瘤免疫应答的实验研究
短句来源
     Specific antitumor immune response induced by pcDNA3.1/MAGE-3-HSP70 fusion DNA vaccine
     pcDNA3.1/MAGE-3-HSP70融合蛋白诱导特异性抗肿瘤免疫应答的研究
短句来源
     Objective To study the biological characteristics of cytotoxicity T lymphocyte(CTL)induced by dendritic cell(DC)transfected with the Epstein-Barr virus latent membrane protein 2A (EBV-LMP2A) recombinant adenovirus.
     目的观察EB病毒(Epstein-Barr virus,EBV)-潜伏膜蛋白2A(latent membrane protein2A,LMP2A)转染人树突状细胞(dendritic cell,DC)诱导特异性细胞毒性T细胞(cytotoxicity Tlymphocyte,CTL)的体外生物学特性;
短句来源
     Human Papillomavirus 16 E7-Specific Cytotoxic Lymphocyte Induction Through Mouse B7-1 Costimulating with E7 of HPV16 or E7C Subgene Fragment
     人乳头瘤病毒16型E7或E7C与共激活分子B7-1协同诱导特异性CTL的研究
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  相似匹配句对
     INDUCTION OF DONOR-SPECIFIC CELLULAR IMMUNOSUPPRESSION
     供体特异性细胞免疫抑制的诱导
短句来源
     THE PREPARATION OF IMMUNOTOXIN AND INDUCE OF IMMUNE UNRESPONSIVENESS
     免疫毒素的制备及特异性淋巴细胞无反应性的诱导
短句来源
     The specificity was also 100%.
     特异性100%。
短句来源
     in troducing stimulus;
     诱导刺激;
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  inducing specific
In rabbits, aluminum-hydroxide(alum)-precipitated native GA733 antigen was superior to alum-precipitated Ab2 in inducing specific humoral immunity.
      
Inducing specific reactivity against B cells in mice by immunizing with an Fc fusion protein containing self-Igβ
      
These anti-mimotope antibodies were capable of inducing specific lysis of 518A2 melanoma cells in ADCC assays with murine effector cells.
      
We found that the peptide CEA694-702 binds weakly to HLA-A*0201 molecules and is ineffective at inducing specific CD8+ T-cell responses in healthy donors.
      
The combination of MHC class I and class II epitopes is more effective than 6B11 in inducing specific cellular immune response against ovarian cancer.
      
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Enriched human peripheral T lymphocytes were exposed to elevated temperature of 40-42℃(heat shock) to mimic the circumstances encountered in vivo under fever.More than ten peptides with different apparent molecular mass have been induced during heat shock.The most predominant peptides synthesized were those with apparent Mr of 71 and 90K.Some minor ones,usually expressed after 3 hours of heat shock were also found.Kinectics of major heat shock protein (HSP) synthesis have been investigated with either different...

Enriched human peripheral T lymphocytes were exposed to elevated temperature of 40-42℃(heat shock) to mimic the circumstances encountered in vivo under fever.More than ten peptides with different apparent molecular mass have been induced during heat shock.The most predominant peptides synthesized were those with apparent Mr of 71 and 90K.Some minor ones,usually expressed after 3 hours of heat shock were also found.Kinectics of major heat shock protein (HSP) synthesis have been investigated with either different heat shock temperature or incorporating labeled amino acids during a prolonged period of heat shock up to 20 hours.

将人外周血富集的T淋巴细胞置于40—42℃(热休克)的环境中培养,以模拟机体发热时细胞所处的环境温度,通过标记氨基酸参入实验发现热休克至少可诱导十余种分子量不同的多肽合成,其中以71,000和90.000d分子量的多肽合成最为旺盛。本文还对主要热休克蛋白的诱导特异性和动力学方面的特点进行了研究和讨论。

Following intramuscular injection of specific transfer factor(S-TF) and immuno-ribonucleic acid(S-iRNA) extracted from the spleens of heavily infected schistosomiasis rabbits and adult schistosome antigen-immunized serum IgG(ISIgG) singly or in combination, the protective immunization against challenge with Schistosoma japonicum cercariae in rabbits was studied. The results were as follows: (1) No protection was found when S-TF or ISIgG was injected alone; (2) Both combinations of S-TF plus ISIgG and S-iRNA...

Following intramuscular injection of specific transfer factor(S-TF) and immuno-ribonucleic acid(S-iRNA) extracted from the spleens of heavily infected schistosomiasis rabbits and adult schistosome antigen-immunized serum IgG(ISIgG) singly or in combination, the protective immunization against challenge with Schistosoma japonicum cercariae in rabbits was studied. The results were as follows: (1) No protection was found when S-TF or ISIgG was injected alone; (2) Both combinations of S-TF plus ISIgG and S-iRNA plus ISIgG could induce specific cellular and humoral immunity which resulted in significant protection against S. japonicum cercarial infection. The time for immunizing injection should be prior to cercarial infection or within 14 days after infection. The authors concluded that S. japonicum schistosomules, and not adult schistosomes, are subjected to the acquired immunity.

采用从血吸虫病重感染兔脾中提取的S-TF和S-iRNA,以及血吸虫成虫抗原免疫血清单独或合并注射家兔,并观察其预防血吸虫感染的结果:(1)单独注射S-TF或血吸虫成虫抗原免疫血清组对血吸虫感染无保护作用;(2)合并注射S-TF加免疫血清IgG,单独注射S-iRNA及合并注射S-iRNA加免疫血清IgG,均能诱导特异性细胞免疫和体液免疫,对血吸虫感染有明显预防作用,但注射时间应在动物感染前或感染后血吸虫未发育至成虫之前。此种获得性免疫仅作用于童虫,对成虫无影响。

Hybridoma (D3) secteing monoclonal anti-idiotype antibody against MS1-5 was produced by fusion of sp2/0 myeloma cells and spleen cells of syngeneic mice immunized with the mixture of MSl-5 D3 was identified with a series of experiments inclu-. ding competitive and neutralizing inhibition ELISA. D3 antibody could induce anti-sporozoite antibody when administered into rabbit and BALB/c mice, on the other hand, rabbit anti-sporozoite could react specifically with D3. It was found that D3 could competitively inhihibit...

Hybridoma (D3) secteing monoclonal anti-idiotype antibody against MS1-5 was produced by fusion of sp2/0 myeloma cells and spleen cells of syngeneic mice immunized with the mixture of MSl-5 D3 was identified with a series of experiments inclu-. ding competitive and neutralizing inhibition ELISA. D3 antibody could induce anti-sporozoite antibody when administered into rabbit and BALB/c mice, on the other hand, rabbit anti-sporozoite could react specifically with D3. It was found that D3 could competitively inhihibit the binding of sporozoite with antisporozoite of various origin, and also neutralized by anti-sporozoite, D3 hybridoma cells could be stained specifically with anti-sporozoite antibody These results showed that anti-idiotype antibody produced by D3 hybridoma is the anti-idiotype dearing internal image of CSP epitope, i. e Ab2 β.

本实验用抗疟原虫子孢子混合单抗MS1—5免疫同系小鼠获得一株抗独特型单克隆抗体(D3)。经竞争抑制ELISA、IFA以及放免中和抑制试验等证实:D3能模拟抗原CSP诱导特异性抗子孢子抗体的产生,使兔抗D3具有抗子孢子的抗体活性。反之,兔抗子孢子抗体又具有抗D3的活性,两者的相互结合既能被异种抗子孢子抗体所中和,又能被抗原所竞争。不仅如此,D3杂交瘤细胞表面的Ig还表现出于孢子抗原决定簇的抗体结合活性。表明D3抗体是一株具有抗原内影像的抗独特型抗体,即Ab2β。

 
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