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  p 16
     p16 positive rate of 11 recurrent adenomas was 0%which was significantly lower than that of 41 non-recurrent adenomas (36.6%) (P< 0.01).
     11例复发组 p16蛋白阳性率为0,显著低于41例未复发组 p16蛋白阳性率36.6% (P<0.01)。
短句来源
     The expressions of p16~ Ink4a and Rb proteins were also related to the pathological grades. The positive rate of p16~ Ink4a was significantly higher in G_2 and G_3 than that in G_1(P<0.05), and that of Rb was significantly lower in G_3 than in G_1 (P<0.05).
     p16Ink4a与Rb蛋白表达与子宫颈腺癌的病理分级有关,G2、G3组p16Ink4a阳性表达率明显高于G1组(P<0·05),G3组Rb阳性表达率明显低于G1组(P<0·05)。
短句来源
     The relative expressions between p16 mRNA and HPV16/18 E7 mRNA showed positive correlation(r=0.813,P<0.01).
     HPV16 / 18E7阳性组 p16mRNA的表达阳性率明显高于阴性组 ,差异有显著性 (t=4 .12 7,P <0 .0 1) ;
短句来源
     Co-negative expressions of p16 and p15 genes and protein in hydatidiform mole which had become invasive or choriocarcinoma were higher than in other cases( χ 2=4.675,P <0.05).
     葡萄胎恶变组P16、P15 蛋白表达联合阴性率高于无恶变组(χ2 = 4.675, P<0.05);
短句来源
     Rusults:The positive rate(18.9%)of p16 in the case with lymphnode metastasis was significantly lower than that(48.0%) without lymphnode metastasis (P <0.05);
     结果 :有淋巴结转移组 p16蛋白阳性率 18.9%显著低于无淋巴结转移组 48.0 % (P<0 .0 5 ) ;
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  “组p16”译为未确定词的双语例句
     Homozygous deletions were found in 35.00%(14/40), 47.06%(8/17), 8.33%(1/12), 45.45%(5/11) and 0%(0/13) of all ALL, HR-ALL, SR-ALL, relapse-ALL and ANLLcases, respectively.
     ALL组p1 6基因纯合子缺失为 35 .0 0 % (1 4/4 0例 ) ,其中HR—ALL为 47.0 6 % (8/1 7例 ) ,SR—ALL8.33% (1 /1 2例 ) ,复发ALL为 45 .45 % (5 /1 1例 ) ,未见点突变 ;
短句来源
     It was found that the rate of DNA hypermethylation in active SLE patients was higher (20/24,83.33%) than that in inactive SLE patients (9/21,42.85%) (x~2= 8.008~b; P=0.005, <0.01; OR=6.67; 95%CI [2.05 ~ 11.29]).
     活动期SLE组p16基因呈甲基化状态者所占比率83.33%(20/24)比非活动期SLE组42.85%(9/21)高,差异也有明显统计学意义(x~2=8.008~b;P=0.005,<0.01;OR=6.67)。
短句来源
     In the group of the survival times of over 3 years and of ander that period the rate was 84.1% and 38.1% respectively( P <0 05).
     生存期 3年以上组p16蛋白阳性率为 84 1% ,显著高于生存期 3年以下组的 38 1% (P <0 0 5 )。
短句来源
     The correletion rate of the two CKIs was 11.1%(4/36),and that of the three CKIs was 2.8%(1/36) in the tumor.
     淋巴转移组P16、P2 7蛋白阴性频率 40 % (6 / 15 )和 2 6 .7% (4 / 15 )明显高于未转移组的 4.8% (1/2 1)和 9.5 % (2 / 2 1) ,但差异无显著性 (P >0 .0 5 ) ;
短句来源
     The positive rate and intensities of staining in survival group were higher than those in death group (P<0.01).
     存活组较死亡组p16蛋白染色阳性率和染色强度高(P<0.01);
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  相似匹配句对
     ] group.
     ]
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     Group B: SD to Wistar rat heart tarnsplantation;
     B
短句来源
     * (16!)
     *(16!)
短句来源
     16 cases were in control groups.
     对照16例。
短句来源
     Control group ;
     对照16例;
短句来源
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  p 16
To provide the highest penetration of the laser emission into a medium, the irradiation of samples were carried out with tuning far from the maximum of the Si-O bond absorption band (1055 cm-1) using the 10P16 line (Ωlas= 947.78 cm-1).
      
In addition to the known nuclear reaction 14N(n, γ)15N, which allows the nitrogen component of explosives to be detected, it is proposed to use the reaction 16O(n, p)16N (β-, γ) → 16O.
      
Multiplex methylation-sensitive PCR was employed in studying the methylation of the RB1 and CDKN2A/p16 promoter regions in 52 retinoblastomas.
      
Methylation of p16 was for the first time observed in retinoblastoma (9 tumors, 17%).
      
Aberrant methylation of the p16 promoter was the second mutation event in two tumors and was not accompanied by RB1 defects in one tumor.
      
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In the eastern part of North China coalfield, there is a distinct difference in coal quality between the Taiyuan formation and Shanxi formation, both being of the Late Paleozoic era. In addition to influences exerted on those formations due to coal petrographical constitutions and the degree of coal metamorphism, there is a third influencing factor, that is, reductivity of coal. Coal reductivity depends on the paleogeographic environment in which the coal-bearing sediments were formed; this is evidenced in manifestations...

In the eastern part of North China coalfield, there is a distinct difference in coal quality between the Taiyuan formation and Shanxi formation, both being of the Late Paleozoic era. In addition to influences exerted on those formations due to coal petrographical constitutions and the degree of coal metamorphism, there is a third influencing factor, that is, reductivity of coal. Coal reductivity depends on the paleogeographic environment in which the coal-bearing sediments were formed; this is evidenced in manifestations both in time and in space. Reductivity is a geochemical feature generally found in the Late Paleozoic coal-bearing sedimentary formations of the district.

我国华北聚煤区东部晚古生代太原组(C_3)和山西组(P_1~1)煤的性质有明显差别,其原因除受煤岩组成和变质程度的影响外,煤的还原性质是第三个影响因素。煤的还原性质受控于含煤建造沉积的古地理环境,在时间上和空间上均有明显的表现。还原性是该区晚古生代含煤建造煤层沉积的一个普遍存在的地球化学特征。

236 female workers exposed to vinyl chloride(VC) and 239 women not exposed to this occupational hazard were examined. The concentrations of VC in workplaces was 1-7 times as the MAC(30mg/M~3) in the examined vinyl chloride polymerization plant and lower in the polyvinyl chloride plastic finishing works. Maternal exposure did not appear to influence on the involuntary infertility and out come of pregnancies or the frequency of major congenital abnomalities, but the incidence of pregnancy toxaemia was found to...

236 female workers exposed to vinyl chloride(VC) and 239 women not exposed to this occupational hazard were examined. The concentrations of VC in workplaces was 1-7 times as the MAC(30mg/M~3) in the examined vinyl chloride polymerization plant and lower in the polyvinyl chloride plastic finishing works. Maternal exposure did not appear to influence on the involuntary infertility and out come of pregnancies or the frequency of major congenital abnomalities, but the incidence of pregnancy toxaemia was found to be higher among the female workers exposed to higher VC. Among 11 pregnant women exposed to VC, the Hb% level and the thrombocyte number were lower than that of the mated control group.The results of animal experiment indicated that the effects of teratogenesis were not found in rats and mice which had been exposed to 5000 ppm VC during pregnancy, however, the embryotoxicity was found. At 10 ppm VC, the embryotoxicity was not appeared. The conception abilities of female animals were not affected at both concentrations.

本文观察了氯乙烯(VCM)对女工及雌性动物妊娠机能及胎儿(仔)发育的影响。共调查了236名氯乙烯作业女工,其中氯乙烯聚合工厂女工106名,车间空气中氯乙烯浓度经常超过卫生标准1—7倍;聚氯乙烯塑料加工女工130名,车间空气中VCM一般不超过卫生标准;以机械加工女工及女售货员239名为对照。结果为氯乙烯作业女工原发性不孕、自然流产及子代先天缺陷的发病率均不高。但氯乙烯聚合工厂女工的妊振高血压综合征发病较高。第一胎妊娠时的发病率为22.6%,相当于对照组女工的1.8倍。11名妊娠女工妊娠28~29周时,血色素含量及血小板计数低于对照女工(p<0.01)。大、小鼠于妊前2周及整个妊娠期以5000 ppm VCM吸入染毒时均未出现致畸,但胎鼠有皮下出血、骨骼发育迟缓、小鼠胎鼠体重低于对照组(p<0.05)。10 ppm染毒时无此等改变。结果认为女工可以参加空气中VCM浓度低于卫生标准的氯乙烯作业,但须加强对妊娠女工的劳动保护。

Le but de ce travail est d'étudier l'influence des différents types des herbes médicinales chinoises (Yang toniques et Yin toniques) sur le système béta-adrénorécepteur-cAMP. L'activité de ce système est mesurée par l'élévation du cAMP plasmique induite par stimulation de l'isoprotérénol (1,8μg/10gm de poids du corps, par vole sous-cutanée, 10 min. avant la collection du sang).L'étude a montré que la réponse de cAMP plasmique à l'isoprotérénol est beaueoup plus grande chez les souris hyperthyroidiennes (L-thyroxin...

Le but de ce travail est d'étudier l'influence des différents types des herbes médicinales chinoises (Yang toniques et Yin toniques) sur le système béta-adrénorécepteur-cAMP. L'activité de ce système est mesurée par l'élévation du cAMP plasmique induite par stimulation de l'isoprotérénol (1,8μg/10gm de poids du corps, par vole sous-cutanée, 10 min. avant la collection du sang).L'étude a montré que la réponse de cAMP plasmique à l'isoprotérénol est beaueoup plus grande chez les souris hyperthyroidiennes (L-thyroxin 0,4mg/souris/jour, sous-cutané, pendant 4 jours) que chez les souris normales (630±41 et 384±27 pmol/ml respectivement, P<0,001). Yang toniques (Racine d'Aconit et Ecorce de Cinnamone lgm par ml de décoction, 0, 6ml/souris/jour, per os, pendant 6 jours) élèvent beaueoup plus la réponse des souris hyperthyoidiennes (979±72, P<0, 01).Par contre, Yin toniques (Racine de Rehmannia 1mg/ml de décoction, 0,6ml/souris/jour, per os, pendant 6 jours) dépriment la réponse des souris hyperthyroidiennes (489±23, P<0,01). La combinaison de Racine de Rehmannia avec Qi toniques (Racine d'Astragalus) montre un effet similaire (409±38, P<0,01).Il est donc de tirer une conclusion que parmi les divers types des herbes médicinales chinoises, les Yang toniques et les Yin toniques peuvent modifier l'activité au système béta-adréno-récepteur-cAMP, au moin dans certaines conditions pathologique. Les actions des Yin toniques et des Yang toniques semblent opposantes les unes les autres et leurs sites d'action sont probablement au niveau des récepteur ou au dessous de celui-là, mais le site d'action exact reste d'(?)tre clarifié.

本实验复制了甲亢小鼠模型,用皮下注射异丙基肾上腺素1.8 ug/10克体重后,以血浆中cAMP定量变化为指标观察了助阳药附桂合剂,滋阴益气药生芪合剂,滋阴药生地煎剂的作用。实验结果:经用异丙肾刺激后,甲亢组cAMP含量(630±40.53)(M±SE,pmol/ml)显著高于正常对照组(384±27.40)(P<0.001)。甲亢服附桂组,其血浆cAMP含量(979±72.14)明显高于甲亢对照组(P<0.01)。甲亢服生芪组,其血浆cAMP含量(409±38.09)明显低于甲亢对照组(P<0.01)。甲亢服生地组,其血浆cAMP含量(489±23.28)亦低于甲亢对照组(P<0.01)。实验结果表明甲亢小鼠的β受体系统对异丙肾的反应性呈现亢进状态,助阳药附桂合剂促进其反应性进一步提高,而滋阴益气药生芪合剂和滋阴药生地能降低其反应性。

 
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