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pc型
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  pc type
    The abdomen is the common primary location, and PC type is predominant in children.
    最常见发病部位为腹腔,PC型组织学类型常见。
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  pc type
Calculations were done on an Apple PC type MacIIcx and on a Micro VAX 3000, considering samples in two and three dimensions at varying particle concentrations.
      
The present article considers problems involved in the representation of Ukrainian text in IBM PC type personal computers.
      
Improvement of nonlinearity and extension of wavelength region using tandem (PV+PC) type HgCdTe detector (Dual-MCT) in FTIR spec
      
A tandem (PV+PC) type HgCdTe detector (Dual-MCT) was fabricated to improve the nonlinear detector response and extend the wavelength region in Fourier transform infrared spectrometer.
      
All data are collected and processed on PC type computers in the situation room at the USCG Base.
      
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Objective The presence of liver fibrosis in patients with beta-thalassemia major has been demonstrated to be an important negative prognostic factor. Identification of liver fibrosis in early stage would be of great value. Hyaluronic acid (HA) , type Ⅲ pre-collagen (PCⅢ), collagen Ⅳ (CⅣ) and laminin (LN) as serum markers were widely used in the diagnosis of liver fibrosis in patients with chronic viral infections or alcoholic liver diseases. However, their values in thalassemic liver fibrosis have not been studied....

Objective The presence of liver fibrosis in patients with beta-thalassemia major has been demonstrated to be an important negative prognostic factor. Identification of liver fibrosis in early stage would be of great value. Hyaluronic acid (HA) , type Ⅲ pre-collagen (PCⅢ), collagen Ⅳ (CⅣ) and laminin (LN) as serum markers were widely used in the diagnosis of liver fibrosis in patients with chronic viral infections or alcoholic liver diseases. However, their values in thalassemic liver fibrosis have not been studied. This work was to determine the serum HA, PCⅢ, CⅣ and LN levels in children with beta-thalassemia major and evaluate the diagnostic utility. Method Serum HA, PCⅢ, CⅣ and LN in 49 hospitalized children with beta-thalassemia major (aged 1-15 years with the media age of 6.27 years) and 41 healthy children served as controls (aged 1-13 years with media age of 6.40 years) were detected by radioimmunoassay (RIA). Forty-five of 49 cases were performed percutaneous liver biopsies, and the histopathological fibrosis was compared with the four serum markers. The correlation and discriminate analysis were used. Results All the serum levels of HA, PCⅢ, CⅣ and LN in beta-thalassemia were significantly higher than those in controls ( P <0.01). In 36 of 45 cases, the histopathology showed liver fibrosis including stageⅠand stageⅡ by biopsies with a positive rate of 80%. The serum levels of four markers increased successively with the aggravation of liver fibrosis from stage 0 to stageⅡ, and significant correlation was observed between the level of HA or PCⅢ and the stage of fibrosis (HA, r =0.379, P =0.017; PCⅢ, r =0.455, P =0.04). While there was no difference between the level of CⅣ or LN and fibrosis (CⅣ, r = 0.312, P =0.053; LN, r =0.310, P =0.055). Using discriminate analysis, the discriminate function of co-detection of the four markers for the diagnosis of fibrosis was 0.002 HA+0.003PCⅢ+0.002CⅣ+0.006LN-1.859, which had a sensitivity of 93.88%, specificity of 68.29%, predictive value of positive test and negative test of 77.97% and 90.32%, respectively. Moreover, there was a significant correlation between the serum level of HA or PCⅢ and the liver iron concentration (HA, r = 0.318, P =0.035; PCⅢ, r =0.305, P =0.044). Conclusion The results suggest that, in beta-thalassemia major with chronic liver disease, HA and PCⅢ showed more practical value in diagnosing liver fibrosis than the levels of CⅣ and LN. The combination of the four serum markers could improve the accuracy and reliability of the diagnosis. A validation study is necessary before introducing into the prediction function during the clinical practice.

目的 探讨血清肝纤维化指标透明质酸 (HA)、Ⅲ型前胶原 (PCⅢ )、Ⅳ型胶原 (CⅣ )和层粘蛋白 (LN)在重型β地中海贫血 (简称 β地贫 )肝纤维化诊断中的价值。 方法 检测 4 9例重型 β地贫患儿和 4 1例正常小儿血清HA、PCⅢ、CⅣ、LN水平 ,其中 4 5例地贫患儿行肝组织学检查 ,进行肝纤维化的对比研究。结果 β地贫组血清HA、PCⅢ、CⅣ、LN四项指标水平均显著高于正常小儿组 (P <0 0 1) ,HA、PCⅢ水平与纤维化分期呈低度正相关 (r=0 379、0 4 5 5 ,P均 <0 0 5 ) ,CⅣ及LN水平与纤维化分期无显著性相关 (r=0 312、0 310 ,P均 >0 0 5 )。四项指标联合诊断肝纤维化的判别函数为 :0 0 0 2HA +0 0 0 3PCⅢ +0 0 0 2CⅣ +0 0 0 6LN - 1 85 9。判断的准确率为 82 16 % ,诊断的灵敏度、特异度、阳性预测价值和阴性预测价值分别为 93 88%、6 8 2 9%、77 97%和 90 32 %。HA、PCⅢ水平的升高与肝脏铁含量有一定的相关性 (r =0 34...

目的 探讨血清肝纤维化指标透明质酸 (HA)、Ⅲ型前胶原 (PCⅢ )、Ⅳ型胶原 (CⅣ )和层粘蛋白 (LN)在重型β地中海贫血 (简称 β地贫 )肝纤维化诊断中的价值。 方法 检测 4 9例重型 β地贫患儿和 4 1例正常小儿血清HA、PCⅢ、CⅣ、LN水平 ,其中 4 5例地贫患儿行肝组织学检查 ,进行肝纤维化的对比研究。结果 β地贫组血清HA、PCⅢ、CⅣ、LN四项指标水平均显著高于正常小儿组 (P <0 0 1) ,HA、PCⅢ水平与纤维化分期呈低度正相关 (r=0 379、0 4 5 5 ,P均 <0 0 5 ) ,CⅣ及LN水平与纤维化分期无显著性相关 (r=0 312、0 310 ,P均 >0 0 5 )。四项指标联合诊断肝纤维化的判别函数为 :0 0 0 2HA +0 0 0 3PCⅢ +0 0 0 2CⅣ +0 0 0 6LN - 1 85 9。判断的准确率为 82 16 % ,诊断的灵敏度、特异度、阳性预测价值和阴性预测价值分别为 93 88%、6 8 2 9%、77 97%和 90 32 %。HA、PCⅢ水平的升高与肝脏铁含量有一定的相关性 (r =0 342、0 30 5 ,P均 <0 0 5 )。结论 血清HA、PCⅢ在重型 β地贫肝纤维化诊断中的价值高于CⅣ及LN ,四项指标联合检测可提高临床诊断的准确性和可靠性。

Objective To investigate the clinical, pathological features of castleman disase (CD) in children. Methods The clinical data, pathological sections and prognosis in 9 cases of CD were analysed. Results There were five boys and four girls, the average age was (8.9 ± 3.2) years. There were 7 localized type and 2 systematic type. Most of localized type patients had local pressure symptoms, and a minor systematic symptoms, such as fever and loss of weight, two systematic type patients had a remarkable systematic...

Objective To investigate the clinical, pathological features of castleman disase (CD) in children. Methods The clinical data, pathological sections and prognosis in 9 cases of CD were analysed. Results There were five boys and four girls, the average age was (8.9 ± 3.2) years. There were 7 localized type and 2 systematic type. Most of localized type patients had local pressure symptoms, and a minor systematic symptoms, such as fever and loss of weight, two systematic type patients had a remarkable systematic sysptoms. Five cases in abdomen, 2 in mediastinum, one at the cervix and the other at the axilla. The diameter of tumors were 2. 5 to 12.0 cm. Microscopically, 6 plasma cell (PC) type, 2 hyaline vascular (HV) type, the other was a mixed variant (MV) type. The follow-up indicated that the prognosis of localized type patients was excellent, while the systematic type was poor. Conclusions It should be thinking of the CD diagnosis when a child has symptoms of long period fever, weight loss, and accompany the mass by B ultrasono-graphy and CT. The abdomen is the common primary location, and PC type is predominant in children. The effect of resecting localized tumor is excellent, while the prognosis of systematic CD is poor

目的探讨Castleman病(CD)的临床及病理形态特征。方法对小儿CD 9例的临床资料、病理切片和随访结果进行分析。结果本组男5例,女4例.年龄(8.9±3 2)岁。局限性7例,系统性2例。局限性病例大多有局部压迫症状,发热、体质量减轻等全身表现较轻;系统性病例均有显著全身表现。肿块位于腹腔5例,纵隔2例,颈部及腋下各1例,肿块直径2.5 ~12.0 cm。镜下浆细胞(PC)型6例,透明血管(HV)型2例,混合(MV)型1例。随访结果示局限性病例预后良好,系统性预后不良。结论小儿有较长时间发热、消瘦,B超及CT等检查有肿块时应考虑CD可能。最常见发病部位为腹腔,PC型组织学类型常见。局限性病例手术切除良好,系统性病例预后不佳。

 
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