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血浆gmp
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  gmp
     Result:Plasma GMP140 and TXB2 levels of high dose GPC were respectively 7.89±1.02ng/ml, 131.71±42.13 pg/ml, significantly lower than those of HFD group.
     结果:高剂量GPC组大鼠血浆GMP140和TXB2含量分别为7.89±1.02ng/ml和131.71±42.13pg/ml,均低于高脂对照组,差别有显著性意义(P<0.05)。
短句来源
     Furthermore,plasma GMP140 content in severe group was significantly higher than that in mild group 〔(3218±681)μg/L vs.(1302±321)μg/L,P<001〕.
     重型组血浆GMP140含量〔(32.18±6.81)μg/L〕明显高于轻型组〔(13.02±3.21)μg/L,P<0.01〕;
短句来源
     The plasma levels of GMP 140,TXB 2 and MPAR in test group were 7.5±0.3 μg/L,237±28 ng/L and (22±4)%, respectively, which were significantly lower than that of control group(9.9±0.5 μg/L,352±46 ng/L and (29±6)% respectively, P <0.05)).
     结果 :试验组冠状静脉窦血浆 GMP- 14 0 ,TXB2 和 MPAR分别为 7.5± 0 .3μg/L、2 33± 2 8ng/L和 (2 2±4 ) % ,均明显高于对照组 (9.9± 0 .5μg/L ,35 2± 4 6 ng/L和 (2 8± 6 ) % ,P<0 5 )。
短句来源
     Results:In patients with congestive heart failure of Qixu Xueyu type the plasma levels of GMP140,TXB 2,6ketoPGF 1α ,and TXB 2/6ketoPGF 1α were significantly higher than those in healthy subject group ( P <0 01 or P <0 001).
     结果:气虚血瘀型心力衰竭患者血浆 G M P 140、 T X B2、6 keto P G F1α及 T X B2 /6 keto P G F1α均较健康组明显增高( P< 001 或 P< 0001)。
短句来源
     Of the patients whose bleeding volume exceeding 50 ml,the GMP140 content was significantly different from that of the patients whose bleeding volume less than 20 ml〔(3958±729)μg/L vs.(1535±390)μg/L,P<001〕.
     出血量>50ml组血浆GMP140含量〔(39.58±7.29)μg/L〕显著高于出血量<20ml组〔(15.35±3.90)μg/L,P<0.01〕;
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     Influence of Tablet of Allicin on Plasmal GMP -140, TXB_2, 6 - K - PGF_(1α), NO and Hemorrheology in Patients of Ischemic Heart Disease
     大蒜素片对缺血性心脏病患者血浆GMP—140、TXB_2、6—K—PGF_(1α)、NO及血液流变学的影响
短句来源
     Results No significant difference existed between the two groups in platelet counts, amount of blood loss and transfusion needed, and plasma GMP-140, TXB_2 and 6-K- PGF_(1α)(t=0.65-1.70,P>0.05).
     ③结果两组间血小板计数、术后出血量及输血量、血浆GMP-140、TXB2和6-K-PGF1α比较差异无显著性(t=0.65~1.70,P>0.05)。
短句来源
     Before and after laser treatment,the GMP-140,6-K-PGF1α and TXB2 were detected.
     ILIB治疗后可使患者血浆GMP - 140、TXB2、TXB2 / 6 -K -PGF1α下降 (P <0 .0 5 )。
短句来源
     Additionally,it was markedly higher in nonsurvivors compared to survivors 〔(3331±845)μg/L vs.(1465±534)μg/L,P<001〕.
     恶化死亡组血浆GMP140含量〔(33.31±8.45)μg/L〕明显高于治愈组〔(14.65±5.34)μg/L,P<0.01〕。
短句来源
     There was a positive correlation between the PAgT and plasma GMP-140 levels in mild、 moderate and severe PIH group(r=0.653,P<0.05;r=0.737,P<0.05;r=0.778,P<0.01 respectively).
     轻、中、重度妊高征 PAgT 与血浆 GMP-140含量水平呈直线正相关关系(r=0.653,P<0.05;r=0.737,P<0.05;r=0.778,P<0.01)。
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  相似匹配句对
     The clinic significance of detecting blood plasma GMP-140 in liverish patients
     肝病患者血浆GMP-140检测及临床意义
短句来源
     The Significance of Determination of Plasma VWF、GMP-140 in Patients with Cerebral Apoplexy
     脑中风患者血浆VWF、GMP-140的检测意义
短句来源
     METHOD OF DETERMINATION FOR PLASMA CATECHO LAMINELEVEL
     血浆儿茶酚胺测定法
短句来源
     Measurement of Testosterone of Plasma by RIA
     血浆睾酮放射免疫测定
短句来源
     QUALITY CONTROL AND GMP MANAGEMENT OF BIOLOGICAL PRODUCTS.
     生物制品的GMP管理
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  gmp
Some other nucleoside phosphates also showed reactivating ability, in the following descending order: AMP = GMP >amp;gt; GDP >amp;gt; GTP >amp;gt; XMP >amp;gt; IMP.
      
Results of experimental implementation of the described algorithms in the GMP system are discussed.
      
coli purine regulon, such as genes involved in general nitrogen metabolism, biosynthesis of pyrimidines, and synthesis of AMP and GMP from IMP, and also upstream of the purine repressor gene.
      
Cyclic GMP-Binding Activity in Avena sativa Seedlings
      
Binding of 3H-labeled cyclic GMP (3H-cGMP) to the structural components of subcellular fractions was studied in oat seedlings.
      
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The platelet function in patients with chronic renal diseases was studied by radioimmunoassay methods. In the patients with nephrotic syndrome, the number of molecules of GMP-14 0 on the platelet surface and in plasma was greatly increased, and the concentrations of TXB2 and 3-TG in plasma was increased as well. In the patients with uremia,increased 3-TG and decreased TXB2 in plasma were found in comparison with those of control. In the patients with chronic glomerulonephritis, the platelet changed only slightly....

The platelet function in patients with chronic renal diseases was studied by radioimmunoassay methods. In the patients with nephrotic syndrome, the number of molecules of GMP-14 0 on the platelet surface and in plasma was greatly increased, and the concentrations of TXB2 and 3-TG in plasma was increased as well. In the patients with uremia,increased 3-TG and decreased TXB2 in plasma were found in comparison with those of control. In the patients with chronic glomerulonephritis, the platelet changed only slightly. These results suggest that the platelet function in patients with nephrotic syndrome and uremia changes greatly and plays an important role in the progress of chronic renal diseases.

利用放射免疫分析研究慢性肾病患者血小板膜表面活化标记蛋白(GMP-140)及血小板代谢、释放产物的变化。结果表明,肾病综合征患者血小板膜表面及血浆GMP-140分子数均明显升高,血浆TXB_2及β-TG显著升高;尿毒症患者血浆β-TG显著升高,血浆TxB_2较正常对照为低,而血小板膜表面及血浆GMP-140分子数未见明显变化;慢性肾小球肾炎患者的上述指标变化不明显。以上结果提示,肾病综合征和尿毒症患者体内的血小板均有明显变化,且对这些疾病的发生和发展起着重要作用。

Radioimmunoassay with two monoclonal antibodies to granule membrane protein (GMP-140) is used to determine whether plasma GMP-140 including its soluble and microparticle forms can be detected in patients with acute myocardial infarction (AMI) or during cardio-pulmonary bypass(CPB) and in platelet concentrates during storage. Monoclonal antibody (McAb) SZ-51 was used as a solid phase and 125I-la-beled McAb SI 2 was used as a fluid phase. The assay showed sufficient sensitivity to detect as few as 1 ng/mL of purified...

Radioimmunoassay with two monoclonal antibodies to granule membrane protein (GMP-140) is used to determine whether plasma GMP-140 including its soluble and microparticle forms can be detected in patients with acute myocardial infarction (AMI) or during cardio-pulmonary bypass(CPB) and in platelet concentrates during storage. Monoclonal antibody (McAb) SZ-51 was used as a solid phase and 125I-la-beled McAb SI 2 was used as a fluid phase. The assay showed sufficient sensitivity to detect as few as 1 ng/mL of purified GMP-140. There was only 10. Orb4. 5 ng/mL in normal plasma (? 20) with no significant difference between the male and the female controls. Ten patients undergoing CPB demonstrated a transient increase in the concentration of plasma GMP-140,especially 2 h after CPB,and its plasma level was inversely correlated with the platelet count during bypass(r=: ?0. 81 ,F<0. 01). Patients with AMI(n=16) were found to have significantly increased concentration of plasma GMP-140 after AMI,reaching the peak within 3 days and changing with the progression of AMI. The concentration of plasma GMP-140 increased progressively in platelet concentrates during storage,particularly 5 days after storage. In short,these data suggest that plasma GMP-140 can be reliably detected by radioimmunoassay with two McAbs to GMP-140 and its plasma level may serve as a useful marker of thrombosis and thrombotic diseases.

利用二株抗人活化血小板α-颗粒膜蛋白(GMP-140)单克隆抗体,建立了血浆内GMP-140含量测定的免疫放射分析法,对急性心肌梗塞、体外循环及库存血小板血浆内GMP-140含量进行了测定。此法能检出1ng/mL纯化的GMP-140,正常血浆内GMP-140浓度为10±4.5ng/mL,男性与女性间无显著差异。体外循环中血浆内GMP-140呈一过性升高,以转流结束后2h为高峰,它的升高与血小板数成负相关(r=-0.81,P血浆GMP-140的浓度,血浆GMP-140的水平是诊断血栓形成及血栓性疾病的有用指标。

The platelet function in patients with chronic renal diseases was studied by radioimmunoassay methods. In the patients with nephrotic syndrome, the number of molecules of GMP-140 on the platelet surface and in plasma was greatly increased, and the concentrations of TXB2 and B-TG in plasma was increased as well. In the patients with uremia, increased B-TG and decreased TXB2 in plasma were found in comparison with those of control. In the patients with chronic glomerulonephritis, the platelet changed only slightly....

The platelet function in patients with chronic renal diseases was studied by radioimmunoassay methods. In the patients with nephrotic syndrome, the number of molecules of GMP-140 on the platelet surface and in plasma was greatly increased, and the concentrations of TXB2 and B-TG in plasma was increased as well. In the patients with uremia, increased B-TG and decreased TXB2 in plasma were found in comparison with those of control. In the patients with chronic glomerulonephritis, the platelet changed only slightly. These results suggest that the platelet function in patients with nephrotic syndrome and uremia changes greatly and plays an important role in the progress of chronic renal diseases.

利用放射免疫分析研究慢性肾病患者血小板膜表面活化标记蛋白(GMP-140)及血小板代谢、释放产物的变化。结果表明,肾病综合征患者血小板膜表面及血浆GMP-140分子数均明显升高,血浆TXB_2及β-TG显著升高;尿毒症患者血浆β-TG显著升高,血浆TXB_2较正常对照为低,而血小板膜表面及血浆GMP-140分子数未见明显变化;慢性肾小球肾炎 患者的上述指标变化不明显。以上结果提示,肾病综合征和尿毒症患者体内的血小板均有明显变化,且对这些疾病的发生和发展起着重要作用。

 
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