Methods Dual- phase helical CT was performed on 21 patients with early pancreatic carcinoma. In the enhanced imaging the contrast material was intravenously injected in a dose of 1.5ml/kg at a rate of 3 ml/s.
Methods Dual- phase helical CT was performed on 21 patients with early pancreatic carcinoma. In the enhanced imaging the contrast material was intravenously injected in a dose of 1.5ml/kg at a rate of 3 ml/s.
Methods Dual- phase helical CT was performed on 21 patients with early pancreatic carcinoma. In the enhanced imaging the contrast material was intravenously injected in a dose of 1.5ml/kg at a rate of 3 ml/s.
Methods Dual- phase helical CT was performed on 21 patients with early pancreatic carcinoma. In the enhanced imaging the contrast material was intravenously injected in a dose of 1.5ml/kg at a rate of 3 ml/s.
Pdx-1, an important transcription factor highlighting in the early pancreatic development, islet functions and pancreatic disorders, needs to be more investigated in zebrafish, and siRNA is still seldom applied in zebrafish embryo-related research.
Only when we understand early pancreatic neoplasms will be able to detect tumors that are curable with surgical resection.
Recently detection of 18q deletions (at the DPC4 locus) in pancreatic secretions from early pancreatic cancers was also reported.
These advances raise the possibility that within well defined at risk groups it will be possible to use a combined set of molecular markers to screen clinical samples and detect early pancreatic cancer or even premalignant lesions.
The homeodomain protein PDX-1, an insulin gene transcription factor, is uniformly expressed in the early pancreatic bud, and null mutation of PDX-1 in mice results in a failure of the pancreatic bud to grow and differentiate.
This paper summerizes 93 cases of pancreas carcinoma demonstrated by CT scan and pathologtcal examination, emphasizing the CT diagnosis of the small pancreas, carcinoma less than 3cm. It showed that the varistion of the contour and the substantial appearance of the pancreas. the irregular and mildly increasing or the little local elevation of the pancreas head, the variation of the processus uncinatus as changed roundly and swellingly, the distention of the pancreas duct and the bile duct were the important...
This paper summerizes 93 cases of pancreas carcinoma demonstrated by CT scan and pathologtcal examination, emphasizing the CT diagnosis of the small pancreas, carcinoma less than 3cm. It showed that the varistion of the contour and the substantial appearance of the pancreas. the irregular and mildly increasing or the little local elevation of the pancreas head, the variation of the processus uncinatus as changed roundly and swellingly, the distention of the pancreas duct and the bile duct were the important sings of the early pancreas carcinoma. It indicates that the dynamic thin CT scan is an effective method to discover and to diagnose the early pancreas carcinoma. The assured rate is 83. 3%.
Abstract The four aspects are discussed in this paper. (1) The present conditions of the management of pancreatic cancer. It is difficult to make early diagnosis of pancreatic cancer,the three fourth of clinical cases is in the advanced stage ( Ⅲ or Ⅳ stage). Surgical resection rate is about 20% ,5-years survival rate is about 10% in resectable patients. In the authors'hospital, surgical resection rate is 9. 1% in 473 cases,5-years survival rate is 7% (3/ 43) in resectable patients. (2) The causes of delayed...
Abstract The four aspects are discussed in this paper. (1) The present conditions of the management of pancreatic cancer. It is difficult to make early diagnosis of pancreatic cancer,the three fourth of clinical cases is in the advanced stage ( Ⅲ or Ⅳ stage). Surgical resection rate is about 20% ,5-years survival rate is about 10% in resectable patients. In the authors'hospital, surgical resection rate is 9. 1% in 473 cases,5-years survival rate is 7% (3/ 43) in resectable patients. (2) The causes of delayed diagnosis and treatment. The misdiagnosis rate is 40. 4% before patients were admitted, preoperative misdiagnosis is still 12. 6% in our 292 cases with pancreatic cancer. The causes of misdiagnosis include difficulty in differential diagnosis with chronic pancratitis and benign obstructive jaundice,the location of tumor (tumor is located in uncinate process of pancreas). 5 misdiagnosed cases are discussed in this section. (3) How to find early cases. The high risk group is the group more than the age of 40 complained of nonspecial gastrointestnal symptoms with the history of pancreatitis or diabetes. After the common gastrointestinal disorders are ruled out, pancreatic cancer should be suspected. (4) How to improve prognosis. Total pancreatectomy decrease the life of quality. It is suggested to perform proper extensive pancreatoduodenectomy, which includs division of pancreas at the left margin of abdominal aorta, division of bile duct at the level of common hepatic duct, division of uncinate process of pancreas closed to the left margin of superior mesenteric artery ,and removal of parapancreatic lymph nodes (en-block resection ). The classical pancreatoduodenectomy is not enough for radical resection of tumor.
The CT features of 67 cases with pancreatic carcinoma proved pathologically were analyzed.The CT appearances of the pancreatic carcinoma were as following:Local enlargement of pancreas occurred in 50 patients(74.6%).Linear soft tissue densities extending into mesentery were found in 8 cases(11.9%)and isodense or homogeneous hypodense masses were seen in 41 cases(61.2%),According to the number of involved vessels,the order of frequency were as following:Inferior vena cava,superior mesenteric vein,superior mesenteric...
The CT features of 67 cases with pancreatic carcinoma proved pathologically were analyzed.The CT appearances of the pancreatic carcinoma were as following:Local enlargement of pancreas occurred in 50 patients(74.6%).Linear soft tissue densities extending into mesentery were found in 8 cases(11.9%)and isodense or homogeneous hypodense masses were seen in 41 cases(61.2%),According to the number of involved vessels,the order of frequency were as following:Inferior vena cava,superior mesenteric vein,superior mesenteric artery,aorta,etc.Enlarged spleens and secondary pseudocysts appeared in 15 and 11 cases respectively.Finally we discussed briefly the difficulties of the early diagnosis of pancreatic carcinoma,the CT features of the secondary pseudocysts and criteria of CT staging of pancreatic carcinoma.
早期胰腺癌
early pancreatic
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