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   肾细胞 在 泌尿科学 分类中 的翻译结果: 查询用时:1.356秒
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  renal cell
Semiquantitative RT-PCR revealed elevated transcription of RHOA in tumors (45 cases of breast cancer, renal cell carcinoma, and epithelial ovarian carcinoma; p >amp;lt; 10-4).
      
There is, for example, no justification for dialysis in a uremic patient with advanced renal cell carcinoma.
      
Late occurrence of renal cell carcinoma metastasis in the right heart detected by cardiac magnetic resonance imaging
      
Cardiac metastasis of a renal cell adenocarcinoma investigated by cardiac magnetic resonance imaging
      
Severe cardiomyopathy in a patient with renal cell carcinoma after treatment with the novel tyrosine kinase inhibitor sunitinib
      
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  renal cells
We studied certain aspects of interaction between (3H)aldosterone and the cytoplasmic as well as nuclear receptors of renal cells in the rats during compensatory renal hypertrophy at the background of reflex renal dystrophy.
      
Angiotensin II (ANG II) has multiple effects on cardiovascular and renal cells, including vasoconstriction, cell growth, induction of proinflammatory cytokines, and profibrogenic actions.
      
ANG II-induced ROS play a pivotal role in several pathophysiologic situations of vascular and renal cells such as hypertension, endothelial dysfunction, nitrate tolerance, atherosclerosis, and cellular remodeling.
      
These findings suggest that pHGF may non-specifically promote the DNA synthesis of renal cells.
      
The results suggested that NaF induces the apoptosis in renal tubules via activation of the Bax expression and Bcl-2 suppression; OPN probably acts as protective role against apoptosis in fluoride-treated renal cells.
      
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  renal-cell
Expression and significance of coxsackie and adenovirus receptor in renal-cell carcinoma
      
Allogeneic stem-cell transplantation in renal-cell carcinoma
      
Metastatic renal-cell carcinoma (RCC) remains resistant to nearly all standard cytotoxic therapies, but immune-based cytokine therapies benefit a small minority of patients with advanced RCC.
      
A phase I-II study of 9-cis retinoic acid and interferon-α2b in patients with advanced renal-cell carcinoma: An NCIC Clinical Tr
      
Although advanced renal-cell carcinoma (RCC) responds poorly to standardtherapies, phase I-II trials have shown activity for combinations ofinterferon-α2b (IFN) with a retinoid.
      
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  renal intracellular
Direct correlations have been observed between the renal intracellular concentration of phosphate ([Pi]i) and postnatal age (3-13 weeks in rats, 1-4 weeks in guinea pigs), as well as between the dietary supply of Pi and [Pi]i.
      


This paper presents 216 cases of ma- lignant renal tumor treated in this hospital during 1957~1984.The patients of over 31 years of age accounted for 86.8% and 6 patients were more than 20 years of age, the youngest being 7 years old.It is of great singnificance.of these 216 patients, 120 were renal cell carcinoma(55.6%), (the most common tumor in kidneys) of which 80 had pathological examination after operation.In this series,75 cases of clear cell carcinoma(91.5%),2 cases of granulose cell carcinoms and 5...

This paper presents 216 cases of ma- lignant renal tumor treated in this hospital during 1957~1984.The patients of over 31 years of age accounted for 86.8% and 6 patients were more than 20 years of age, the youngest being 7 years old.It is of great singnificance.of these 216 patients, 120 were renal cell carcinoma(55.6%), (the most common tumor in kidneys) of which 80 had pathological examination after operation.In this series,75 cases of clear cell carcinoma(91.5%),2 cases of granulose cell carcinoms and 5 cases of undiffirentiated renal cell carcinoms were found.In this series.75 cases had ne- phrotectomy.Follow-up studies that the three-yeat survival rate was 47.1% and the five-year survival rate was 32.9% The survival rate for 23 cases was more than 5 years,of which 17 cases were proved to be stage 1 and 6 stage 11,sug- gesting that in order to improve the survi- val rate,to early diagnosis and proper treatment must be paid special attentioe.

本文报告了我院1957~1984年共收治的肾脏恶性肿瘤216例其中肾细胞癌120例(55.6%),占肾脏肿瘤的第一位。有82例通过手术及活组织检查得到病理结果,透明细胞癌76例(占91.5%),颗粒细胞癌2例,未分化癌5例。在患者中31岁以上者占86.7%,而20岁以下者6例,其中年龄最小者为7岁(1例),值得注意。本组中75例做了肾切除术。术后随访,三年存活率为47.1%,五年存活率为32.9%,有23例存活五年以上。其中Ⅰ期17例,Ⅱ期6例。因此在今后应尽早诊断、治疗肾肿瘤,以提高长期存活率。

Although it is now generally accepted that renal cell carcinoma (RCC) arises from proximal convoluted tubules (PCT), there are some features of RCC difficult to interpret by the hypothesis. We employed four monoclonal antibodies (mAbs) against different tubules to determine the antigenic expression of adult kidney and RCC with the avidin-biotin peroxidase complex (ABC) technique.The results in 38 adult kidney showed: the mAb Uro-2 stained intensively the epithelial cell of PCT and weakly glomeruli; the mAb against...

Although it is now generally accepted that renal cell carcinoma (RCC) arises from proximal convoluted tubules (PCT), there are some features of RCC difficult to interpret by the hypothesis. We employed four monoclonal antibodies (mAbs) against different tubules to determine the antigenic expression of adult kidney and RCC with the avidin-biotin peroxidase complex (ABC) technique.The results in 38 adult kidney showed: the mAb Uro-2 stained intensively the epithelial cell of PCT and weakly glomeruli; the mAb against Tamm-Horsfall glycoprotein reacted with the cellular membranes of ascending thick limb of Henle's loop and distal tubules (DCT); the mAb Uro-5 bound to the epithelial cells of DCT, collecting ducts (CD); the mAb Uro-10 outlined the PCT. On the basis of immunoanatomic study of normal kidney we used these mAbs to detect the antigens of 32 cases of RCC. 13 cases (40.6%) only expressed the antigns of PCT and indicated the origin of this site. Five cases (15.6%) presented exclusively the antigen of DCT and were considered arising from the cells of them. Two cases 'had the antigen of CD and suggested deriving from this segment of nephron.Analysing the data in the literature and our results we have come to a preliminary conclusion that (1) not all RCC originate from the PCT, besides this portion of the nephron RCC also derive from the other segments of renal tubules, including DCT and CD; (2) the staining patterns of the mAbs are typical and consistent, and useful in immuno-microanatomy of kidney.

近年公认肾细胞癌起源于近曲小管,作者应用4种肾小管抗原的单克隆抗体(mAb)对38例成人肾及32例肾细胞癌进行免疫组化研究;发现这些mAb在肾脏有稳定的染色类型,肾细胞癌多数表达近曲小管抗原,少数表达远曲小管、集合管抗原。经肿瘤细胞类型分析,透明细胞癌主要起源于近曲小管,颗粒细胞癌可能起源于远曲小管。

30 cases ot RCC, including 16 clear, 1 spindle and 6 mixed (clear and granular), were carefully compared in their ultrastructural characteristics. The clear, granular and spindle cell type of RCC were not different in nature but rather in the quantity of lipid, glycogen and mitochondria present. So, ultrastructually, RCC may be classified into 3 types: that rich in lipid and/or glycogen (clear), that rich in mitochondria (granular) and that poor in lipid and mitochondria (spindle). It was also found that the...

30 cases ot RCC, including 16 clear, 1 spindle and 6 mixed (clear and granular), were carefully compared in their ultrastructural characteristics. The clear, granular and spindle cell type of RCC were not different in nature but rather in the quantity of lipid, glycogen and mitochondria present. So, ultrastructually, RCC may be classified into 3 types: that rich in lipid and/or glycogen (clear), that rich in mitochondria (granular) and that poor in lipid and mitochondria (spindle). It was also found that the degree in ultrastructural differention can be of value in prognosing the RCC.

本文对30例肾细胞癌(包括16例透明细胞型,7例颗粒细胞型,1例梭形细胞型和6例透明细胞与颗粒细胞混合型)的超微特征进行了仔细的比较。在电镜下,透明细胞、颗粒细胞和梭形细胞之间除了脂滴、糖原和线粒体的数量有所不同之外,并无本质上的差异。因此,本文建议将肾细胞癌分为三个超微结构类型:富于脂滴和/或糖原型(透明细胞型),富于线粒体型(颗粒细胞型)和脂滴和线粒体贫乏型(梭形细胞型)。超微结构的分化程度可能具有预后价值。

 
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