Studies on the Mechanism of Imbalance of Inflammatory Mediators and Anti-inflammatory Mediators in the Development of Acute Lung Injury by Endotoxin and the Protective Effects of Interleukin-10 and Dexamethasone
The pathogenesy of smoke inhalation acute lung injury/acute respiratory distress syndrome(ALI/ARDS) is not completely clear,perhaps concerned with oxidative damage,the change of pulmonary surfactant and cytokine,and apoptosis.
Acute lung injury (ALI), the acute and diffuse injuries to lung tissues caused by various factors, is mainly characterized by inflammatory over-reaction and increased permeability of alveolar-capillary membranes.
(2) The expression of NF-κB in the LPS group was significantly higher than that in the control group, (P<0.05), the inflammatory cell in the lung was higher than in the control group(P<0.05), and the pathomorphology in lung tissue showed sever injuries.
Results Compared with those of group A,the small airways in group B showed that the tissues and cells were injured and the inflammatory cells infiltrated the airway walls,and the average areas of alveolus increased(P<0.05).
Our studies demonstrated an in vivo cardioprotection effect of (N-(3,4,-dimethoxy-2-chlorobenzylideneamino)-guanidine: ME10092) in ischaemic reperfusion injury in the rodent.
Diclofenac (25 mg kg-1) and meloxicam (7.5 mg kg-1) produced 9.3 and 19.6 mm2 ulcer areas in stomachs of rats, respectively, when used alone, but when combined with nimesulide diclofenac and meloxicam did not cause any injury in rat stomachs.
These proteins may be involved in cardiovascular injury, and could play an important role in the treatment of coronary heart disease.
SOD and POD activities declined correspondingly, followed by significant increases of MDA and MP, and leaf injury was finally observed.
Hepatocellular injury was the predominant type in these cases (132 cases, 48%).
The proportion of acute drug-induced liver disease among all of the acute liver injuries was annually increased.
In the course of the solution of the originated minimization problem, it becomes possible to define the class of systems that involves the object under consideration with the preliminary accumulation of injuries in cancer cells.
It is assumed that without such a preliminary accumulation of injuries, the immune action does not lead to the extinction of cancer cells.
β-Blocker propranolol was shown to exert an antidystrophic effect in the case of local injuries of the neural system and, thus, prevented the development of neurogenic dystrophies.
Local capillary blood flow was studied in and around the spinal cord compression focus in humans with spinal injuries in the acute and early periods of the trauma.
The polyvinyl acetal sponge modified by chitosan was used as a hemostatic packing material for the injured rabbit nasal tissue.
Effects of Elicitors on the Accumulation of Proteinase Inhibitors in Injured Potato Tubers
Drug blockade of both neural and humoral transmission of the abnormal stimuli from the injured nerve to the kidney prevented development of trophic disorders as indicated by the status of the renal mineralocorticoid receptor system.
This adhesion protein significantly induced proliferation of corneal epithelial cells relative to control groups with the injured eyes treated with the serum adhesion protein at the same concentration or water.
Structural properties of regenerating muscle and the state of thymus after laser therapy of injured muscle in different periods