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bcr
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  bcr
     Syp Y279, Y304 Can Mediate the Binding of Bcr Abl to Grb2 and Other Proteins
     S(yp) Y279和Y304介导了BcrAbl与Grb2等蛋白的结合
短句来源
     Immunoprecipitation and Immunoblot have found that WT, Y279F, Y304F and Y546F Syp can bind directly to the Bcr Abl in vivo.
     免疫沉淀与免疫印迹结果发现WT、Y279F、Y304F和Y546F等4 种Syp 在胞内均能直接与BcrAbl 结合。
短句来源
     Results Apoptosis of K562 cells was significantly increased associated with inhibition of bcr abl expression.
     结果bcrabl融合基因表达受抑后,K562细胞凋亡显著增加。
短句来源
     Conclusion bcr abl fusion gene formation due to chromosome translocation may be the major mechanism of CML via inhibition of apoptosis.
     结论bcrabl融合基因可抑制CML细胞凋亡,这可能是CML发病的主要机制。
短句来源
     Objective To investigate the effect of bcr abl fusion gene on CML cell apoptosis.
     目的研究bcrabl融合基因在慢性粒细胞白血病细胞(CML)凋亡调控中的作用。
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  “bcr”译为未确定词的双语例句
     mutation of Syp Y304F can block the binding of Shc SH2 to Syp in vitro.
     结论是: 作为“接头蛋白”,Syp 可以介导BcrAbl 与Shc 和Grb2 之间的结合;
短句来源
     Objective:The current study was designed to investigate the specific killing effects against homo-leukemia hybrid cell induced b y BCR-ABL multiple epitope fusion pr otein and explore a powerful chronic myeloid leukemia(CML )immunotherapeutic strategy.
     目的:观察多表位BCRABL融合抗原在体外激发的免疫反应对同源白血病融合细胞的杀伤效应,探索慢性髓性白血病chronicmyeloidleukemiaCML免疫治疗的新途径。
短句来源
     Method:A multiple epitope antigen gene of BCR-ABL fusion antigen was used to immunize C57BL /6mice and the sple en cells were cultured as effective c ells. Specific lytic activities of t arget cells were detected by standard MTT assay.
     方法:用人工合成含有不同HLAhumanleukcyteantigen限制性的BCRABL多个表位的融合蛋白免疫C57BL/6小鼠,取小鼠脾细胞进行体外培养,以四唑盐MTT比色法测定鼠CTLscytotoxiclymphocytes介导的特异性杀伤效应。
短句来源
     Results:Only the CTLs (cytotoxic lymphocytes)of mice immunized with the fusion pro tein can lyse the target cells but not the c ontrol cells(P<0.01vs P>0.05). Conclusion:The multiple epitope BCR-ABL fusion antigen elicited antigen-sp ecific,CTL-mediated anti-leukemi a immune responses which provided a b asis for further study on the developing specific T cell immunotherapy of CML in vivo.
     结果:融合抗原激发产生的鼠CTL能特异性杀伤靶细胞(P<0.01但不杀伤对照组靶细胞(P>0.05。结论:设计的多表位BCRABL融合抗原能激发特异性免疫反应,并对同源白血病细胞产生特异性杀伤,为进一步实验奠定了关键基础。
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  相似匹配句对
     Gly.
     Gly。
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     Results Apoptosis of K562 cells was significantly increased associated with inhibition of bcr abl expression.
     结果bcrabl融合基因表达受抑后,K562细胞凋亡显著增加。
短句来源
     Objective To investigate the effect of bcr abl fusion gene on CML cell apoptosis.
     目的研究bcrabl融合基因在慢性粒细胞白血病细胞(CML)凋亡调控中的作用。
短句来源
     Some gene model for mammalian sex determination such as Zgene model and DSSgene model etc.
     X连锁的DAX基因;
短句来源
     (3) later processing of BCR.
     (3) BCR的后处理的一些知识。
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  bcr
Cross plots of Mrs/Ms versus Bcr/Bc and χfd% versus χarm/saturation isothermal remanent magnetization (SIRM) indicate that the main magnetic grain sizes in surface soil are pseudo single domain (PSD) and multidomain (MD).
      
Imatinib inhibits the activity of chimeric kinase BCR-ABL, which is responsible for the development of CML.
      
For example, the magnetic fields obtained for two magnetars with P=5.16 s and P=7.47 s are Bs=1.7×1013 and 2.9×1013 G, which are lower than the critical field Bcr=4.4×1013 G.
      
This is a consequence of the linearly growing term ?B/Bcr present in the vacuum polarization in an asymptotically strong magnetic field.
      
The quasi-stationary regime of electron leakage across the high magnetic field (B0/Bcr >amp;gt; 1.1, where Bcr is the insulation critical field) is realized.
      
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A pre-irradiation chemical seperation neutron activation analysis and instrumental epithermal neutron activation analysis are used for determination of trace elements in DZΣ-1 and DZΣ-2 std. The analytical method and experimental condition are discussed. Analytical results are shown in tables. Trace elements of USGS standard samples, BCR-1, BIR-1 and PCC-1 are simultaneouslyd etermined. The results are in agreementwith the values published.

本文介绍用化学前处理中子活化和超热中子活化分析方法,测定了两个超铁镁岩石标样DZΣ-1和DZΣ-2的微量元素。较详细地讨论了测试方法和条件,并将微量元素的分析值列于表中。为了检查工作的可靠性,对USGS发行的岩石标样BCR-1,BIR-1及PCC-1同时进行测定,其分析值与文献值基本符合。

A typical pottery sample has been prepared by mixing unearthed potshards from Song, Yuan and Ming dynasties in certain proportion. The potshards sample are cleaned, dried, ground and sieved, and 200 mesh powder is selected. The powdered sample is dried again before being sealed in polyethylene bottles, The sample is analysed for 24 elements(Sm, Ce, Lu, Yb, Nd, La, Tb, Eu, U, Th, Hf, As, Cs, Sb, Sc, Rb, Cr, Zn, Ta, Co, Ba, Fe,Na and K by INAA and K0 method. As a control for accuracy, standard reference materials...

A typical pottery sample has been prepared by mixing unearthed potshards from Song, Yuan and Ming dynasties in certain proportion. The potshards sample are cleaned, dried, ground and sieved, and 200 mesh powder is selected. The powdered sample is dried again before being sealed in polyethylene bottles, The sample is analysed for 24 elements(Sm, Ce, Lu, Yb, Nd, La, Tb, Eu, U, Th, Hf, As, Cs, Sb, Sc, Rb, Cr, Zn, Ta, Co, Ba, Fe,Na and K by INAA and K0 method. As a control for accuracy, standard reference materials SRM 1632a, BCR-1, GXR-4 and JG-1 are analysed. The agreement between our results and literature values is satisfactory.

按比例选取宋、元、明三个朝代具有代表性的瓷器碎片,制成标准样。利用仪器中子活化分析的相对法和K_0法测定了这个样品中24种元素(Sm,Ce,Lu,Yb,Nd,La,Tb,Eu,U,Th,Hf,As,Cs,Sb,Sc,Rb,Cr,Zn,Ta,Co,Ba,Fe,Na,K)的含量。同时平行的测定了国际标准参考物SRM1632a,BCR_(-1),GXR_(-4)和JG_(-1)。这些国际标准参考物的测定值与文献值是一致的。

The expressions of the borehole apparent complex resistivity(BCR)spectra for the buried volume-polarized sphere and spheroid are derived byd.c. electric field theory and the Cole-Cole relaxation model. In theelectrical image method, the asymmetrical influence of the imaginary andreal sphere on subsurface stations can be conducted by means of stackingmulti-geometrical factors which include Legendre function of variousindependent variables. The shape of the spectra curve is simpler than thatof the ground...

The expressions of the borehole apparent complex resistivity(BCR)spectra for the buried volume-polarized sphere and spheroid are derived byd.c. electric field theory and the Cole-Cole relaxation model. In theelectrical image method, the asymmetrical influence of the imaginary andreal sphere on subsurface stations can be conducted by means of stackingmulti-geometrical factors which include Legendre function of variousindependent variables. The shape of the spectra curve is simpler than thatof the ground spectra, because of getting smaller ground noise to subsurfacestations, and better for distinguishing sources. The BCR method can beexecuted in azimuthal measurements. The results are useful for thelocalization of a polarized body.

基于直流电场中球及椭球的电位函数及柯尔-柯尔张驰模型,导出地下埋藏体积极化球和椭球体井中视复电阻率解析表达式。镜象法实、虚球对地下测点作用不对称的问题,用多个含不同宗量勒让得函数的几何因子逐点迭加来解决。井中视复电阻率谱受地面影响小,曲线形态比地面谱更简单,更利于区分异常源的性质;其方位测量剖面曲线可判断极化体赋存位置。

 
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