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血清丙二醛     
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  serum malondialdehyde
     Methods The levels of serum malondialdehyde(MDA) and super-oxide dismutase(SOD) in 68 APP patients were measured by the methods of thiobarbiturate and xanthin oxidase at the time of hospitalization,24h,48h,72h after poisoning,and compared with 29 healthy individuals.
     方法采用硫代巴比妥酸法及黄嘌呤氧化酶法测定68例APP患者入院当时、中毒后24h、48h、72h及29例正常对照组血清丙二醛(MDA)及超氧化物歧化酶(SOD)的含量。
短句来源
     Objective To explore the relationship between the changes of serum malondialdehyde(MDA),superoxidation dismutase (SOD) and the level of serum-estriol (E 3), β-hCG, and expression of estrogen receptors(ER), HCG on placenta of intrahepatic cholestasis of pregnancy(ICP).
     目的 探讨妊娠肝内胆汁淤积症 (intrahepatic cholestasis of pregnancy,ICP)患者血清丙二醛 (MDA)和超氧化物岐化酶 (SOD)含量的变化与游离雌三醇 (E3 )和胎盘雌激素受体 (ER)水平之间的关系。
短句来源
     The levels of serum malondialdehyde(MDA),T-SOD,Mn-SOD,GSH-pxwere observed in 36 patients with coronary heart disease(CHD),22 hypertension and 25 no-mal subjects.
     本文观察了36例冠心病患者,22例高血压病患者血清丙二醛(malondialdehyde,MDA)、总超氧化物岐化酶(T-SOD)、锰-超氧比物岐化酶(Mn-SOD)、谷胱甘肽过氧化物酶(GSH-px)水平,并与25例正常人进行对照。
短句来源
     Then we examine their serum malondialdehyde (MDA) and superoxide dismutase (SOD), compare the difference of MDA and SOD every group, analysis the correlation of MDA and SOD with BMD.
     检测各组研究对象的血清丙二醛(MDA)、超氧化物歧化酶(SOD),比较各组之间的MDA、SOD的不同,分析MDA、SOD与BMD的相关性。
短句来源
     On 51st day, measuring the serum malondialdehyde (MDA), superoxide dis mutase (SOD) and glutathione peroxidase(GSH-Px).
     第 51天测血清丙二醛 (MDA)含量、超氧化物歧化酶(SOD)和谷胱甘肽过氧化物酶 (GSH -Px)活性 ;
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  serum mda
     In addition,the diets supplemented with taurine at 0.005%,0.02%,0.04% and 0.08% decreased the concentration of serum MDA in the later period(P<0.05).
     另外,日粮中添加牛磺酸降低了试验后期蛋鸡血清丙二醛含量,其中0.005%、0.02%、0.04%、0.08%组差异显著(P<0.05)。
短句来源
     ① Activity of serum SOD in model group was lower than that in other three groups (P < 0.05-0.01), and level of serum MDA in model group was higher than that in normal control group and ligustrazine + massage group (P < 0.01), but level in ligustrazine group was similar to that in model group.
     ①模型组大鼠血清超氧化物歧化酶活力明显低于其他3组(P<0.05~0.01),血清丙二醛水平明显高于正常对照组和川芎嗪+按摩组(P<0.01),川芎嗪组血清丙二醛水平与模型组相近。
短句来源
     The contents of serum MDA in RI group was also higher than other groups (P<0.01 or 0.05).
     再灌注损伤组血清丙二醛含量明显高于其它各组(P<0.01或0.05);
短句来源
     The contents of serum MDA in RI group was also higher than other groups (P<0.01).
     RI组的血清丙二醛含量明显高于其他各组(P<0.01);
短句来源
     The spleen T lymphocyte proliferation, IL-2 production and serum MDA were measured.
     测定小鼠T淋巴细胞功能,IL-2和血清丙二醛(MDA)水平。
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  serum levels of malondialdehyde
     The serum levels of malondialdehyde (MDA), superoxide dismutase (SOD) and estradiol(E_2)were determined and compared.
     检测各组研究对象的血清丙二醛(MDA)、超氧化物歧化酶(SOD)及雌二醇(E2),比较各组之间的MDA、SOD及E2的不同并分析MDA、SOD与E2的相关性。
短句来源
     Serum levels of malondialdehyde (MDA), superoxide dismutase (SOD), interleukin 6 (IL 6) and tumor necrosis factor α (TNF α) in patients' venous blood were measured at different time points, and the integrated left ventricular ejection isometric index (Tei) was determined by echocardiogram.
     分别在术前及术后不同时间点测定血清丙二醛 (MDA)、超氧化物歧化酶 (SOD)、白细胞介素 6 (IL 6 )、肿瘤坏死因子 (TNF α)水平 ,用超声心动图测定左心室综合射血等容期 (Tei)指数。
短句来源
     Objective: The serum levels of malondialdehyde (MDA), superoxide dismutase (SOD) and nitric oxide (NO) were measured to find out the clinical index in GDM.
     目的 :测定妊娠期糖尿病 (GDM)孕妇血清丙二醛 (MDA)、超氧化物歧化酶 (SOD)和一氧化氮(NO)含量 ,寻找监测GDM病情变化的临床指标 .
短句来源
     Methods:Serum levels of malondialdehyde (MDA),serum glutathione peroxidase (GSHPx) and serum superoxide dismutase (SOD) in 36 nondialyzed patients with various degrees and 12 hemodialyzed(HD) were determined with the method of chemistry colorimetry.
     方法 :采用化学比色法 ,对 36例 CRI患者、12例血液透析患者和 16例正常人的血清丙二醛 (MDA)、谷胱甘肽过氧化物酶(GSH Px)及血清超氧化物歧化酶 (SOD)的含量进行了检测。
短句来源
     Methods: Sixteen patients with MODS and ARF after cardiac surgery and sixteen healthy people were included in the study. The serum levels of malondialdehyde(MDA) ,superoxide dismutase(SOD), glutathione peroxidase(GSH-Px) and total anti-oxidant capacity(TAC) and MODS scores were examined and registered. The correlation between MODS scores and biomarkers of oxidative stress was analyzed.
     方法测定16例经体外循环心脏术后MODS伴ARF患者及16例健康人的血清丙二醛(MDA)、超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)、总抗氧化能力(TAC),同时对患者进行MODS评分,并将评分与氧化应激参数进行相关性分析。
短句来源
更多       
  serum levels of malonaldehyde
     Methods: Serum levels of malonaldehyde (MDA) and superoxide dismutase (SOD),glutathione peroxidase (GSH Px) were detected in 32 cases of ITP by RIA,and treatment of vitmine C was given.
     方法:采用放免法测定ITP血清丙二醛(MDA),总超氧化物歧化酶(TSOD)、锰超氧化物歧化酶(MnSOD)、谷胱甘肽过氧化物歧化酶(GSHPx)水平,并给予维生素C治疗。
短句来源
     Methods The plasma levels of β EP and the serum levels of malonaldehyde (MDA),superoxide dismutase (SOD) were measured by radioimmunoassay (RIA) in 46 patients with cerebral infarction in the acute stage,compared with those of 30 normal controls.
     方法 应用放射免疫分析法对 46例急性脑梗塞患者血浆β-内啡肽 (β- EP)及血清丙二醛 (MDA)、超氧化物歧化酶 (SOD)含量进行测定。
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      serum malondialdehyde
    Heat exposure increased concentrations of serum malondialdehyde (MDA) (p=0.001), glucose, and cholesterol (p=0.01), which were elevated by supplemental Diachrome (p≤0.05).
          
    Thus, increased serum malondialdehyde levels may be a sign of carcinoma.
          
    Disease activity score correlated positively with serum malondialdehyde level and CuZn superoxide dismutase activity.
          
    Our results revealed a significantly higher level of serum malondialdehyde, selenium in patients with active disease compared with the controls.
          
    Pre and post race serum malondialdehyde (MDA), creatine kinase (CK) and lactate dehydrogenase (LDH) levels were studied in runners following an 80 km (50 mile) race.
          
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      serum mda
    Separately or as a combination vitamins C and E increased serum vitamin C and vitamin E concentrations (p>amp;lt;0.001) but decreased serum MDA concentration (p>amp;lt;0.05).
          
    Serum concentrations of vitamin E and vitamin C were found highest but serum MDA concentration was lowest in the combination group.
          
    No children had increased serum MDA concentrations and the value is not influenced by the Zn concentration.
          
    Serum MDA concentrations were detected in terms of TBARS (thiobarbituric acid reactive substances) spectrophotometrically.
          
    The results of the study show that, separtely or as a combination, zinc and vitamin A supplementation resulted in an improved live weight gain, feed efficiency, and carcass traits, as well as a decrease in serum MDA concentrations.
          
    更多          
      serum levels of malondialdehyde
    Serum levels of malondialdehyde (MDA), α-tocopherol, cholesterol, albumin and ascorbic acid, and α-tocopherol/cholesterol ratio were determined.
          
    We examined serum levels of malondialdehyde, selenium, vitamin E and A, and the erythrocyte activities of glutathione peroxidase, superoxide dismutase, and catalase.
          
    Serum levels of malondialdehyde and 4-hydroxy-2,3-nonenal in patients affected by familial chronic nail candidiasis
          
    The serum levels of malondialdehyde and total antioxidative activity were measured.
          


    The kinetic changes of the amount of malonyldialdehyde ( MDA ) in the sera obtained from mice infected with Plasmodium berghei at different time after infec tion were investigated, using a simple fluorometric assay. Infected mice exhibited a linear increase of the amount of MDA in the sera, which was closely correlated with the degree of anemia and Parasitemia.The data suggest that the en hanced lipid peroxidation may be one of the causes leading to anemia and other pathological damages in the infected mice;...

    The kinetic changes of the amount of malonyldialdehyde ( MDA ) in the sera obtained from mice infected with Plasmodium berghei at different time after infec tion were investigated, using a simple fluorometric assay. Infected mice exhibited a linear increase of the amount of MDA in the sera, which was closely correlated with the degree of anemia and Parasitemia.The data suggest that the en hanced lipid peroxidation may be one of the causes leading to anemia and other pathological damages in the infected mice; it may also play a role in the oxidative killing of malaria parasites in vivo.

    本文采用TBA荧光法测定了伯氏疟原虫感染小鼠后不同时期小鼠血清中丙二醛的含量,结果表明小鼠血清丙二醛含量呈直线升高,并与原虫血症和贫血程度密切相关。提示脂质过氧化反应增强.可能是导致鼠体内溶血及其他病理损伤的原因之一,也可能在介导对疟原虫的氧化杀伤中起部分作用。

    Six hours after inhalation pulmonary injury,the pulmonary microvascular permeability (PMVP),pulmonary malondialdehyde (MDA) level,superoxide dismu-tase activity (SOD),the contents of protein and leucocytes in broncho-alveolar lavage fluid(BALF),and serum MDA level were determined in rats pretreated with allopurinol.In addition,the pathological changes of the lung tissues were also studied.It was found that early administration of allopurinol resulted in marked reduction of PMVP,and the protein content and leucocyte...

    Six hours after inhalation pulmonary injury,the pulmonary microvascular permeability (PMVP),pulmonary malondialdehyde (MDA) level,superoxide dismu-tase activity (SOD),the contents of protein and leucocytes in broncho-alveolar lavage fluid(BALF),and serum MDA level were determined in rats pretreated with allopurinol.In addition,the pathological changes of the lung tissues were also studied.It was found that early administration of allopurinol resulted in marked reduction of PMVP,and the protein content and leucocyte count in BALF.His-topathological examinations revealed that allopurinol could reduce the leucocyte accumulation in pulmonary vessels,interstitial leucocyte infiltration,interstitial and alveolar edema and hemorrhage,and vascular congestion.The serum and pulmonary levels of MDA also markedly decreased.The changes of pulmonary level of MDA were parallel to those of PMVP,and the protein content and leucocyte count in BALF in time course and in degree.The results listed here imply that the mechanism of the therapeutic effects of allopurinol on inhalation pulmonary injury is to reduce the production of superoxide anions through the inhibition of xanthine oxidase,in turn to inhibit the peroxidation of pulmonary lipids to alleviate pulmonary damage.

    本实验采用大鼠烟雾吸入模型,观察了预先给予别嘌呤醇对吸入性肺损伤后6h内肺微血管通透性、丙二醛生成、超氧化物歧化酶活性、肺灌洗液中蛋白浓度及白细胞计数和血清丙二醛的影响,并辅以肺脏病理检查。结果表明:别嘌呤醇对吸入伤大鼠可以显著降低肺微血管通透性,减少肺灌洗液中蛋白含量及白细胞计数,组织病理学检查也可见肺充血、出血、间质和肺泡水肿减轻,白细胞浸润减少等。别嘌呤醇在减轻肺水肿的同时,也使肺及血清丙二醛水平明显降低,而肺组织丙二醛含量的变化在伤后6h内与肺微血管通透性、肺灌洗液中蛋白含量及白细胞计数的变化在时间及程度上都一致。以上结果提示,别嘌呤醇通过抑制黄嘌呤氧化酶,减少超氧阴离子产生,从而抑制肺脂质过氧化,减轻吸入性肺损伤。

    This study was performed to investigate the possible source of lipid peroxides in atherosclerotic aorta with experimental atherosclerosis. We found that the level of serum malondialdehyde, a key intermediate in the formation of peroxides (58.82±8.43 vs.13.03±0.63μmol/L, P<0.001), and the activity of blood superoxide dismutase (403.65±21.35 vs. 289.35± 8.65U/ml, P<0.00l) were higher in experimental group than control. The results suggested that the lipid peroxides in atherosclerotic aorta probably resulted from...

    This study was performed to investigate the possible source of lipid peroxides in atherosclerotic aorta with experimental atherosclerosis. We found that the level of serum malondialdehyde, a key intermediate in the formation of peroxides (58.82±8.43 vs.13.03±0.63μmol/L, P<0.001), and the activity of blood superoxide dismutase (403.65±21.35 vs. 289.35± 8.65U/ml, P<0.00l) were higher in experimental group than control. The results suggested that the lipid peroxides in atherosclerotic aorta probably resulted from serum peroxides and that the increased superoxide dismutase activity was a defence mechanism against an increased level of free radicals in the blood.

    本实验利用动脉粥样硬化动物模型,观察了血清脂质过氧化产物(丙二醛)与血液超氧化物歧化酶(SOD)活力的变化情况。实验发现,动脉粥样硬化家免血清丙二醛与血液SOD活力均明显升高。结果提示,血清脂质过氧化物可能是动脉壁中脂质过氧化物的主要来源,血液SOD活力升高是对自由基损伤的代偿性防御反应。

     
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