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羟基维生素d
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  “25羟基维生素d3”译为未确定词的双语例句
     The results showed that urinary THP/Cr was elevated in children with rickets,The correlative analysis showed that there was a negative correlation between the urinary THP/Cr and the serum 25(OH)D 3.There was a postive correlation between the urinary THP/Cr and the serum ALP.
     相关分析显示尿THP/Cr与血清25羟基维生素D3(25(OH)D3)呈负相关,与血清碱性磷酸酶(ALP)呈正相关。
短句来源
     Methods: Thirty eight patients with epilepsy and thirty controls were involved. Serum calcium(Ca),serum phosphorum(P),alkaline phosphate(ALP),bone alkaline phosphate(BAP),bone gla protein (BGP),parathormone(PTH),25 hydroxy vitamim D 3 (25(OH) D 3 )and calcitonin(CT) were measured in healthy controls and in treatment group before,3 and 6 month after antiepileptic drugs treatment.
     方法 :正常对照组 30例 ,癫痫患者组 38例 ,于抗癫痫药(患者组 )治疗前 ,治疗后 3个月、6个月分别测定血钙 (Ca)、磷 (P)、碱性磷酸酶 (ALP)、骨特异性碱性磷酸酶(BAP)、骨钙素 (BGP)、甲状旁腺素 (PTH)、2 5羟基维生素D3 [2 5 (OH)D3 ]、降钙素 (CT)等生化指标。
短句来源
     But BAP and PTH levels were higher while BGP, CT and 25(OH)D 3 levels were lower than those before treatment.
     骨钙素、降钙素、2 5羟基维生素D3 均较治疗前下降 (P <0 .0 1 )。
短句来源
     Conclusion: AEDs can influence bone metabolism in patients treated with epilepsy, and BAP, PTH, BGP, CT and 25(OH)D 3 levels are sensitive markers of bone in formation and absorption.
     结论 :抗癫痫药可导致癫痫患者骨代谢异常 ,其中骨特异性碱性磷酸酶、甲状旁腺素、骨钙素、降钙素、2 5羟基维生素D3 可作为骨形成和骨吸收的敏感指标
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  相似匹配句对
     Determination of 25-OH-D_3 concentration in human serum by HPLC
     HPLC法测定血中25-羟基维生素D_3的含量
短句来源
     STUDY ON 25(OH)D_3 LEVELS FOR THE EARLY DIAGNOSIS OF RICKETS
     血清25羟基维生素D_3对佝偻病早期诊断的研究
短句来源
     Vitamine E3.2%;
     维生素E3.2%;
短句来源
     Immunomodulatory effects of 1,25-dihydroxyvitamin D3
     1,25-二羟维生素D3的免疫调节作用
短句来源
     Evaluation of serum 25-hydroxy vitamin D level in children of Beijing
     北京市儿童血清25羟基维生素D的水平探讨
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  25 (oh) d 3
10 μg pro Tier und Tag sowie von 400 μg 25(OH)D3 pro Tier und Tag hatten keinen Einflu? auf die Erkrankung.
      
The 25(OH)D3 levels were comparable in both groups.
      
There was no correlation between the 25(OH)D3 and 1,25(OH)2D3 concentrations.
      
A sensitive liquid chromatography-electrospray ionization-tandem mass spectrometric (LC-ESI-MS/MS) method for the determination of 25-hydroxyvitamin D3 [25(OH)D3] in human saliva has been developed and validated.
      
The PTAD derivative was much more easily ionized in positive-ESI-MS and efficiently produced a characteristic product ion during MS/MS, compared to the intact 25(OH)D3.
      
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1 α 25-dihydroxy-vitamin D3(1α 25 (OH)2 D3)induced differentiation of human promyelocytic leukaemia cells ( HL-60 ) into mature myeloid cells in vitro. The ratio of nuclei to cytoplasma decreased; Their nucleoli reduced; Cells became irrgular and extended the pseudopods. 1 α 25 (OH ) 2 D3 caused significant increase of nitroblue tetrazolium ( NBT ) reduction and α-non-specific acid esterase (α-NAE ) and acid phosphatase (ACP ) activities. These data and morphological characteristics suggest that HL-60 cells...

1 α 25-dihydroxy-vitamin D3(1α 25 (OH)2 D3)induced differentiation of human promyelocytic leukaemia cells ( HL-60 ) into mature myeloid cells in vitro. The ratio of nuclei to cytoplasma decreased; Their nucleoli reduced; Cells became irrgular and extended the pseudopods. 1 α 25 (OH ) 2 D3 caused significant increase of nitroblue tetrazolium ( NBT ) reduction and α-non-specific acid esterase (α-NAE ) and acid phosphatase (ACP ) activities. These data and morphological characteristics suggest that HL-60 cells were conclusively identified as monocytes/macrophages. The histogram of DNA distribution ahylyzed by flow cytometry demonstrated G0 + G1 phase increased and S phase increased and S phase decreased remarkably after treatment with lα, 25 ( OH ) 2 D3 as compared with untreated cells.

1α,25二羟基维生素D_3在体外可诱导HL-60细胞向单核/巨噬样细胞发展。在形态上,核/质比例减少,核仁减少,细胞变得不规则并伸出伪足;在细胞化学方面,细胞对NBT还原能力增强,α萘酚醋酸酯酶和酸性磷酸酶阳性率明显增加,细胞周期的变化是:二倍体细胞明显增多,G_0+G_1期增加和S期减少。表明在1α,25(OH)_2D_3作用下,HL-60细胞向成熟分化,细胞DNA合成受抑制。

Serum concentration of 25-hydroxyvitamin D [25(OH)D_3] in 592 Beijing normal subjects (age: O-87 years), 256 cases maternal and cord blood and 361 patients with 20 different disorders (altogether1209 subjects) were determined by competitive protein binding assay. Decreased serum levels of 25(OH)D_3 compared with normal ware observed in patients with rickets, tetany, pneumonia infantilehepatitis, bone tumor, diabetes and renal disease and increased serum levels of 26 (OH) D_3 was inpatients with Vitamin D overdose...

Serum concentration of 25-hydroxyvitamin D [25(OH)D_3] in 592 Beijing normal subjects (age: O-87 years), 256 cases maternal and cord blood and 361 patients with 20 different disorders (altogether1209 subjects) were determined by competitive protein binding assay. Decreased serum levels of 25(OH)D_3 compared with normal ware observed in patients with rickets, tetany, pneumonia infantilehepatitis, bone tumor, diabetes and renal disease and increased serum levels of 26 (OH) D_3 was inpatients with Vitamin D overdose and fatty liver. Serum values of 1,25-dihydroxyvitamin D_3 [1,25(OH)_2D_3] were detected by radioreceptor assay in35 Beijing normal subjects, 28 cases of maternal and cord blood and 68 patients (131 in total). Serumvalues of 1,25(OH)_2D_3 was lower than normal in uremic, nephrotic syndrome and osteoporotic patientsand higher than normal in pregnant women. The results show that the variations of serum 25(OH)D_3 and 1,26(OH)_2D_3 are valuble indicatorsfor diagnosis, evaluating treatment and prognosis of metabolic bone disease.

本文采用竞争性蛋白结合法(CPBA)测定1209例受检者血清25羟基维生素D_3[25(OH)D_3],其中包括0~87岁健康人592例,孕妇与新生儿256例,患者361例(20个病种);并采用放射受体法测定131例受检查者血清1,25二羟基维生素D_3[1,25(OH)_2D_3],其中健康人35例,孕妇与新生儿28例,患者68例。结果表明,血清25(OH)D_3和 1,25(OH)_2D_3水平的变化对钙磷代谢失调及代谢性骨病的诊断、评价治疗和预后有重要参考意义。

The hydroxycolecalciferol preparations(including its analogs) and its clinical uses are introduced. The emphasis is put on the methods of preparing stabilized preparations. Its uses in cosmetics and dermatoses are briefly mentained.

简述羟基维生素D_3(活性V_(D3),包括相关物质)的临床应用及制剂。着重介绍了制备稳定的活性V_(D3)制剂的方法。并涉及其在透皮吸收制剂、化妆品方面的应用。

 
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