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目的确定    
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  objective to determine
    Objective: To determine the influence of age on ke0 and EC_(50) of propofol when MAP was regarded as the index of effect.
    目的 :确定以MAP作为效应指标时 ,年龄对丙泊酚效应位的消除速率常数 (ke0 )和 5 0 %最大效应的效应位浓度 (EC50 )的影响。
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    Objective: To determine whether glutamine-supplemented parenteral nutrition improves nitrogen retention and reduces hospital morbidity compared with standard parenteral nutrition after bone marrow transplantation.
    目的:确定骨髓移植后补充谷氨酰胺的肠外营养与标准肠外营养液比较能否改善氮潴留,减少住院并发症。
短句来源
    Objective To determine the effects of platelet activating factor antagonist BN52021 for urine electrolytes excretion in control rats or in rats with nephrotic syndrome.
    目的确定血小板活化因子拮抗剂BN52021对正常和肾病大鼠尿电解质排泄的影响。
短句来源
    Objective To determine the frequent of ulnar nerve instability and its relationship to ageand ligament rdaxation in children.
    目的确定儿童尺神经不稳定的多发性及其与年龄和韧带松弛之间的关系。
短句来源
    Objective: To determine factors related to brain edema after γ knife radiosurgery.
    目的 :确定伽玛刀 (γ-刀 )治疗后脑水肿发生的相关因素。
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  objective to confirm
    OBJECTIVE:To confirm correlative factors of axillary lymph nodes metastasis from breast cancer and metastasis disciplinarian, and discuss the signification that the lymph node situation serves as prognosis of breast cancer.
    目的 :确定与乳腺癌腋窝淋巴结转移相关因素及转移规律 ,探讨淋巴结状况作为乳腺癌预后因素的意义。
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  aim to determine
    AIM: To determine the ultimate preservation time of murine cardiac grafts in 4℃ Ringer's solution.
    目的 :确定小鼠心脏移植的供心在体外 4℃林格氏液中保存时间的极限。
短句来源
    AIM: To determine the irreversible time limit of skeletal muscle in ischemic rabbits at 4 ℃and 6 ℃so as to provide a fast and reliable preoperative detecting index for the limb replantation.
    目的:确定4℃和6℃条件下缺血兔骨骼肌的不可逆变性时限,为断肢再植提供一种快速、可靠的术前检测指标。
短句来源
    AIM: To determine the influence of topical anaesthetic drops, age and central corneal thickness (CCT) in the determination of intraocular pressure (IOP) by non contact tonometry (NCT).
    目的:确定局麻药,年龄和角膜中央厚度对非接触眼压计眼压测量值的影响。
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  objective to determine
Objective To determine if organic vegetable soups have a higher salicylic acid content than non-organic vegetable soups.
      
Objective To determine factors influencing the wide variation of protein concentration in lumbar cerebrospinal fluid (CSF).
      
OBJECTIVE To determine whether Bcl-2 protein down-regulation can render NCl-460 cells more susceptible to gamma radiation-induced apoptosis by treatment with antisense oligonucleotide (ASODN) against the coding region of Bcl-2 mRNA.
      
OBJECTIVE To determine the ideal method of surgical preoperative treatment for perforation with esophageal carcinoma.
      
OBJECTIVE To determine the effect of short interference RNA (siRNA) against STAT3 induced inhibition of STAT3 gene expression and on the growth and apoptosis of Lewsis lung cancer cells.
      
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  aim to determine
A system consisting of a cold target and "hot" atoms generated by dissociation of tritium on a tungsten wire was studied with the aim to determine conditions for preparing tritium-labeled organic compounds with the maximal radiochemical yield.
      
The reaction of carboxymethyl polysaccharides and their ethyl esters with amines was studied with the aim to determine how the structure of the polymeric acylating agent affects the composition of the reaction products.
      
The complex study of barium metaborate crystals has been undertaken with the aim to determine the conditions of their growth with the minimum density of inclusions.
      
Aim To determine the shunt volume of iatrogenic arteriovenous fistula (AVF) following arterial puncture of the groin and to evaluate its impact on natural history and clinical outcome.
      
Dose response experiments aim to determine the complication probability as a function of dose.
      
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  objective to define
Each of these initiatives has the threefold objective to define, measure, and monitor quality.
      


Objective: To determine whether glutamine-supplemented parenteral nutrition improves nitrogen retention and reduces hospital morbidity compared with standard parenteral nutrition after bone marrow transplantation. Design:Double-blind,randomized,controlled clinical trial. Setting: University teaching hospital. Patients:Forty-five adults receiving allogeneic bone marrow transplants for hematologic malignancies. Intervention: Parenteral nutrition was intitiated the day after bone marrow transplantation (day 1).The...

Objective: To determine whether glutamine-supplemented parenteral nutrition improves nitrogen retention and reduces hospital morbidity compared with standard parenteral nutrition after bone marrow transplantation. Design:Double-blind,randomized,controlled clinical trial. Setting: University teaching hospital. Patients:Forty-five adults receiving allogeneic bone marrow transplants for hematologic malignancies. Intervention: Parenteral nutrition was intitiated the day after bone marrow transplantation (day 1).The experimental solution was supplemented with L-glutamine (0. 57g/ kg body weight per day)and provided estimated erquirements for energy and protein. The control solution was a standard,glutamine-free,isonitrogenous,isocaloric formula. Measurements:Nitrogen balance was determined between days 4 and 11 in the initial 23 patients. The incidence of clinical infection and microbial colonization,time until bone marrow engraftment,indices of clinical care,and other data related to hospital morbidity were recorded for all patients.Results:The glutamine-supplemented patients ( n = 24) were clinically similar to the controls ( n= 21) at entry. Nutrient intake was similar in both groups;However,nitrogen balance was improved in the glutamine-supplemented patients relative to the controls ( - 1. 4±0. 5g/d compared with -4. 2±l. 2; P =0. 002). Fewer experimental patients developed clinical infection (three compared with nine in the control group;P=0. 041),and the incidence of microbial colonization was also significantly reduced. Hospital stay was shortened in patients receiving glutamine supplementation (29±1 d compared with 36±2 d, P =0.017).Conclusion: patients receiving glutamine-supplemented parenteral nutrition after bone marrow transplantation had improved nitrogen balance,a diminished incidence of clinical infection,lower rates of microbial colonization, and shortened hospital stay compared with patients receiving standard parenteral nutrition. These effects occurred despite no differences between groups in the incidence of fever,antibiotic requirements,or time to neutrophil engraftment.

目的:确定骨髓移植后补充谷氨酰胺的肠外营养与标准肠外营养液比较能否改善氮潴留,减少住院并发症。设计:双盲、随机和对比临床研究。位置:大学教学医院。病人:45位因血液系恶性瘤而接受同种异体骨髓移植的成年人。介入:肠外营养从骨髓移植后的第一天开始。研究组补给L-谷氨酰胺(0.57g·kg~(-1)·d~(-1)),并供给估计需要的能量和蛋白质。对照组给予标准的、不含谷氨酰胺的、等氮等热卡营养液。监测:在开始的23个病人中,第4至第11天之间测定氮平衡,记录临床感染和细菌植入的发生率,至骨髓生长的时间,临床医疗指标及其他与住院并发症有关的数据。 结果:研究开始时补充谷氨酰胺组(n=24)病人的临床情况与对照组(n=21)病人类似。两组病人的营养摄入相仿。然而,与对照组相比,补充谷氨酰胺组病人的氮平衡改善(-1.4±0.5g/d比-4.2±1.2g/d,P=0.002)。研究组病人发生临床感染者更少(3例比对照组的9例,P=0.041)。细菌植入的发生率也明显降低。接受谷氨酰胺的病人住院时间缩短(29±1天比36±2天,P=0.017)。 结论:与接受标准肠外营养液的病人相比,接受谷氨酰胺肠外营养液的病人在骨髓移...

目的:确定骨髓移植后补充谷氨酰胺的肠外营养与标准肠外营养液比较能否改善氮潴留,减少住院并发症。设计:双盲、随机和对比临床研究。位置:大学教学医院。病人:45位因血液系恶性瘤而接受同种异体骨髓移植的成年人。介入:肠外营养从骨髓移植后的第一天开始。研究组补给L-谷氨酰胺(0.57g·kg~(-1)·d~(-1)),并供给估计需要的能量和蛋白质。对照组给予标准的、不含谷氨酰胺的、等氮等热卡营养液。监测:在开始的23个病人中,第4至第11天之间测定氮平衡,记录临床感染和细菌植入的发生率,至骨髓生长的时间,临床医疗指标及其他与住院并发症有关的数据。 结果:研究开始时补充谷氨酰胺组(n=24)病人的临床情况与对照组(n=21)病人类似。两组病人的营养摄入相仿。然而,与对照组相比,补充谷氨酰胺组病人的氮平衡改善(-1.4±0.5g/d比-4.2±1.2g/d,P=0.002)。研究组病人发生临床感染者更少(3例比对照组的9例,P=0.041)。细菌植入的发生率也明显降低。接受谷氨酰胺的病人住院时间缩短(29±1天比36±2天,P=0.017)。 结论:与接受标准肠外营养液的病人相比,接受谷氨酰胺肠外营养液的病人在骨髓移植后氮平衡改善,临床感染的发生率减少,细菌植入的发生率降低,住院时间缩短。而两组病人的发热发生率,抗菌素需要和中性粒细胞生?

To identify the accuracy and reliability of magnetic resonance angiography (MRA) in evaluating patients with lower peripheral vascular disease. Two-dimensional time-of-flight (2D TOF) MRA was used to evaluate 132 arterial segments in patients. Of which, 49 segments in six patients were studied with conventional arteriography. MRA findings were compared with that of the angiography. In 132 segments, MRA showed normal in 102 comfirmed by angiographies in all 35 undergoing arteriographies, and abnormal in 30 (mild...

To identify the accuracy and reliability of magnetic resonance angiography (MRA) in evaluating patients with lower peripheral vascular disease. Two-dimensional time-of-flight (2D TOF) MRA was used to evaluate 132 arterial segments in patients. Of which, 49 segments in six patients were studied with conventional arteriography. MRA findings were compared with that of the angiography. In 132 segments, MRA showed normal in 102 comfirmed by angiographies in all 35 undergoing arteriographies, and abnormal in 30 (mild stenosis in nine. significant stenosis in 11, occlusions in eight, and aneurysms in two) identified by angiographies in 14. In the 49 segments e valuated by both MRA and angiography, a good correlation between these two imaging modalities was found in 47 of the 49 segments, and a poor correlation in two because of loss of blood flow on the MR angiogram after implantation of a Strecker stent in one, of technical limitation in another one. 2D TOF MRA is accurate and reliable in evaluating the patency of the lower extremity arteries.

本文目的是确定二维TOF法磁共振血流成像对下肢周围血管性疾病诊断的准确性和可靠性。15例患者132段血管用二维TOF法磁共振血流成像检查,其中6例患者49段血管同时进行了常规血管造影检查。在132段血管中,MRA检查显示正常血管102段,异常血管30段。在30段异常血管中,轻度狭窄9段,明显狭窄11段,完全闭塞8段,动脉瘤2段。在同时进行MRA和常规血管造影检查的49段血管中,正常血管35段,异常血管14段。二者显示一致47段,仅2段显示有差异,其中1段是由于动脉内Strecker支架置入引起MRA信号丢失,考虑血管闭塞,而血管造影显示血管明显狭窄。另一段MRA显示一侧髂总动脉轻度狭窄,而血管造影正常。我们的研究结果证明MRA对下肢周围血管性疾病,特别是闭塞性血管疾病有较高准确性和可靠性。如能适当应用扫描序列和参数,将使其能达到常规血管造影对周围血管性疾病诊断的精确性。

Objective To determine the effects of platelet activating factor antagonist BN52021 for urine electrolytes excretion in control rats or in rats with nephrotic syndrome.Methods Made the model of nephrotic syndrome in rats with adriamycin, observed urine eletolytes excretion in rats injected with BN52021.Results We found that on the 7th day after BN52021, sodium and chloride excretion in urine was increased from 2.4876±0.1862 and 1.5149±0.2087 mmol/24h in control rats to 3.9806±1.0896 and 2.2400±0.6449 mmol/24h...

Objective To determine the effects of platelet activating factor antagonist BN52021 for urine electrolytes excretion in control rats or in rats with nephrotic syndrome.Methods Made the model of nephrotic syndrome in rats with adriamycin, observed urine eletolytes excretion in rats injected with BN52021.Results We found that on the 7th day after BN52021, sodium and chloride excretion in urine was increased from 2.4876±0.1862 and 1.5149±0.2087 mmol/24h in control rats to 3.9806±1.0896 and 2.2400±0.6449 mmol/24h in rats treated with BN52021; potassium excretion in urine was decreased from 1.2479±0.0547 in control ratsto 0.4507±0.2118 in rats treated with NB52021 (Ps<0.01); the Na+-K+-ATPase activity in rat renal medulla was inhibited in rats treated with BN52021 (4.6±1.1μmol P·mg-1 protein·h-1,in control rats vs. 1.8±1.7μmol P·mg-1 protein·h-1 in BN rats,P<0.01).Conclusion BN52021 inhibits reabsorption of sodium and chloride, and inhibits excretion of potassium in rat kidneys, the effects were found to be related to the inhibition of the activity of Na+-K+-ATPase in the renal medulla.

目的确定血小板活化因子拮抗剂BN52021对正常和肾病大鼠尿电解质排泄的影响。方法制备大鼠阿霉素肾病模型,观察NB52021使用后大鼠尿电解质的排泄情况。结果用BN52021后1周,大鼠尿Na+排泄量从对照组的2.4876±0.1862mmol/24h增加到处理组的3.9806±1.0896mmol/24h,Cl-1排泄量从1.5149±0.2087mmol/24h增加到2.2400±0.6449mmol/24h,而K+的排泄则从1.2479±0.0547mmol/24h减少到0.4507±0.2118mmol/24h(P均<0.01);且BN52021处理的大鼠,肾髓质的Na+-K+-ATP酶活性为1.8±1.7μmolP·mg-1蛋白·h-1,较对照组的4.6±1.1μmolP·mg-1蛋白·h-1(P<0.01),明显受到抑制。结论BN52021抑制大鼠肾脏Na+、Cl-1的重吸收及K+的分泌,这一作用与大鼠肾髓质的Na+、K+-ATP酶活性的抑制有关。

 
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