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   浅表性膀胱癌 的翻译结果: 查询用时:0.058秒
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浅表性膀胱癌     
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  superficial bladder cancer
     the expression of Ang-2、VEGF was found to be more intense inhigher grades(G2-G3),and invasive(≥T2)bladder cancer than that in lower grade (G1)and superficial bladder cancer (p<0.05);
     高分级(G2~3)组Ang-2、VEGF 的表达高于低分级(G1)组,浸润性膀胱癌(≥T2 期)组Ang-2、VEGF 的表达高于浅表性膀胱癌(
短句来源
     The clinical use of BCG-CWS and IL-2 for preventing recurrence of superficial bladder cancer
     BCG-CWS联合IL-2预防浅表性膀胱癌术后复发
短句来源
     The correlation between recurrence of superficial bladder cancer and histology manifestation or Ki-67, p53 expression
     浅表性膀胱癌组织学形态及Ki-67、p53表达与肿瘤复发的关系
短句来源
     Results Positive expression of endostatin was found in 61.5% patients with superficial bladder cancer,90.6% with invasive bladder cancer and 33.3% in normal bladder tissues.
     结果 浅表性膀胱癌组内皮抑素表达率 6 1.5 % ,浸润性癌组为 90 .6 % ,正常膀胱组织为 33.3%。
短句来源
     Objective To approach the correlation between histology manifestation or Ki-67, p53 expression and superficial bladder cancer.
     目的探讨浅表性膀胱癌组织学形态以及Ki67、p53表达与肿瘤复发的关系。
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  superficial bladder carcinoma
     Methods187 patients with superficial bladder carcinoma after TUR-Bt operation were randomly divided into the group A (85 cases) and group B (102 cases). Patients of the group A were treated with instillation of Brucea Javanica oil emulsion;
     方法187例浅表性膀胱癌TUR-Bt术后患者随机分为A组(85例)和B组(102例),A组应用鸦胆子油乳膀胱灌注,B组灌注丝裂霉素预防肿瘤复发。
短句来源
     Methods A total of 36 patients with superficial bladder carcinoma (10 cases of T a and 26 of T 1;11 cases of G 1,20 of G 2 and 5 of G 3) underwent partial cystectomy.
     方法 浅表性膀胱癌 36例 ,Ta10例 ,T12 6例 ; G111例 ,G2 2 0例 ,G3 5例 ,均行膀胱部分切除。
短句来源
     Methods 49 cases of (stages Ta-1,grades1-2)superficial bladder carcinoma with average age of 60 were recruited. 34 Cases were received TURBT and 15 of which were given partial cystectomy.
     方法 浅表性膀胱癌(Ta -1,G1-2 ) 49例,平均年龄60岁,施行经尿道膀胱电切(TURBT) 3 4例,部分膀胱切除15例。
短句来源
     47 postoperative patients with stages Ta to T1 primary superficial bladder carcinoma of grades 1or 2 were randomized into groups A: single 80 mg epirubicin;
     将 4 7例浅表性膀胱癌 (Ta~l,G1~ 2 )入选患者随机分为 3组 ,A组 ( 16例 )患者术后 6h内单次灌注表柔比星 80mg ; B组 ( 15例 )术后定期灌注表柔比星 4 0mg ,至术后 1年 ;
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     Objective To investigate the correlation between intravesical drug therapy and mdr 1 gene expression in superficial bladder carcinoma.
     目的探讨浅表性膀胱癌MMC和BCG/MMC膀胱灌注疗效与mdr1表达的相关性。
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  superficial bladder tumor
     Clinical grade by UICC: superficial bladder tumor ( Tis ~ Tl) period 23 cases, invasive bladder tumor (12 ~T4) period 28 cases .
     临床分期按UICC标准:浅表性膀胱癌Tis~T1期23例,浸润性膀既癌h-T4期28例。
短句来源
     The stromal expression of TIMP-2 would be an indicator of determining the recurrence of superficial bladder tumor.
     TIMP 2在间质中表达可作为判断浅表性膀胱癌复发的预后指标
短句来源
     Objective To study a new and practical method to prevent the superficial bladder tumor recurrence after transurethral resection of bladder tumor (TUR-Bt).
     目的 探讨预防浅表性膀胱癌经尿道膀胱肿瘤电切术 (TUR Bt)术后复发的新方法。
短句来源
     Methods: Partial cystectomy has been carried out for 13 cases of superficial bladder tumor and 5 cases of infiltrative cancer from April 1993 to December 1996.Before and in operation,intravesical instillation and submucosal local infiltrative injection with MTX have been used seperately.
     方法 :对 1 3例浅表性膀胱癌和 5例浸润性膀胱癌施以膀胱部分切除术 ,术前行 MTX膀胱灌注 ,术中和术后分别行 MTX膀胱粘膜下注射和直肠粘膜下注射 ,术后行小剂量 BCG膀胱灌注。
短句来源
     Methods We compared the effect of intravesical epirubicin or mitomycin C on tumor recurrence and disease free interval and their side effects after treatment of superficial bladder tumor.
     方法 了解表柔比星单次与多次灌注预防浅表性膀胱癌术后复发的长期疗效 ,并与丝裂霉素疗效比较。
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  primary superficial bladder carcinoma
     47 postoperative patients with stages Ta to T1 primary superficial bladder carcinoma of grades 1or 2 were randomized into groups A: single 80 mg epirubicin;
     将 4 7例浅表性膀胱癌 (Ta~l,G1~ 2 )入选患者随机分为 3组 ,A组 ( 16例 )患者术后 6h内单次灌注表柔比星 80mg ; B组 ( 15例 )术后定期灌注表柔比星 4 0mg ,至术后 1年 ;
短句来源
     Efficacy and safty of different dosages of intravesical epirubicin instillation for prevention of primary superficial bladder carcinoma from recurrence
     不同剂量表柔比星膀胱灌注预防浅表性膀胱癌复发的疗效与安全性
短句来源
     Conclusion Early postoperative single high dose intravesical instillation of epirubicin combined with repeated lower doses of the same drug every month may be an efficient and safe regimen to prevent the primary superficial bladder carcinoma from recurrence.
     结论表柔比星术后早期、单次、大剂量灌注配合每月1次低剂量灌注预防浅表性膀胱癌复发,可能是一种安全、经济、有效的方法。
短句来源
     Objective To investigate the efficiency and safety of different regimens by intravesical instillation of epirubicin, a derivative of adriamycin, for the prevention of primary superficial bladder carcinoma from recurrence.
     目的比较不同剂量表柔比星膀胱灌注预防浅表性膀胱癌术后复发的疗效和安全性。
短句来源
     Single instillation of epirubicin for the prophylaxis of recurrent primary superficial bladder carcinoma
     单次腔内灌注表柔比星预防浅表性膀胱癌术后复发
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  superficial bladder cancer
Presently, one of the most potent immunotherapies is the application of bacillus Calmette Guerin (BCG) to prevent recurrences of the superficial bladder cancer.
      
It could as possibly prove to be an effective intravesical treatment agent for superficial bladder cancer.
      
Substantial changes have been made in the therapeutic options for the management of superficial bladder cancer in the past 5 years.
      
Treatment goals for superficial bladder cancer are complete removal of the initial tumor, prevention of disease recurrence, and inhibition of progression to invasive disease.
      
This article reviews the pros and cons of a second staging TURBT and how it may impact the management of high-grade, low-stage superficial bladder cancer.
      
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  superficial bladder carcinoma
(Bacillus Calmette Guérin) has proven to be effective in the prophylaxis of recurrence of superficial bladder carcinoma after transurethral resection and in the treatment of carcinoma in situ (C.I.S.) in man.
      
The main problems presented by superficial bladder carcinoma, its high recurrence rate and multifocal appearance, require treatment of the bladder as a whole.
      
Photodynamic therapy (PDT) is one such experimental treatment for superficial bladder carcinoma, involving the administration of a photosensitizer that accumulates in the tumor tissue, and subsequent irradiation of the tumor with light.
      
The results show that ALA-induced photosensitization has a high potential for photodynamic therapy (PDT) of superficial bladder carcinoma.
      
In intravesical therapy for superficial bladder carcinoma urothelial cells may, through the production of cytokines, contribute to the bacillus Calmette-Guérin (BCG)-induced local immunological reaction and associated antitumor efficacy.
      
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  superficial bladder tumor
Large cooperative trials are more likely than series studied by small groups to bring about significant progress in the field of intravesical adjuvant chemotherapy of superficial bladder tumor
      
From October 1983 to September 1985, 84 patients with superficial bladder tumor (Ta, Tl, Tis) were treated with sequential instillation of mitomycin C (MMC) and adriamycin (ADM).
      
In superficial bladder tumor, abnormal expression of E-cadherin and a-catenin was demonstrated in 37 and 71% of the tumors, respectively.
      
Analysis of the expression of MAUB and MUC2 mucins in a human superficial bladder tumor specimen.
      
  其他


From January 1981 to December 1990 50 patients of superficial bladder cancer used Long-term intravesical instillation with mitomycin C in prophylaxis of recurrence after operation. The duration ranged from 16~94 (average 62) months. Complete response 60%, partial response 16%. No systemic effect on bone morrow suppression. Mitomycin C appeared to be a safe drug, but further studies are indicated when used as maintenance therapy.

对50例病人长期用丝裂霉素C膀胱内灌注预防浅表性膀胱癌术后复发,随访16~94个月,总有效率为76%。丝裂霉素C无骨髓抑制的全身副作用,持续应用证明安全有效。

23 cases of carcinoma of carcinoma of urinary bladder were treated postoperatively by intramuscular injection of IL-2 and intravesical irrigation of TTP from April 1989 to Oct 1992.Mean time of follow-up was 32 months.Only 2 cases had become recurrent(8.7%).Some complication of reversible leukopenia had happened.

对23例浅表性膀胱癌患者手术后联合应用IL-2肌注和TTP 灌注膀胱,预防膀胱癌术后复发。经随访平均32个月,复发2例,占8.7%。并发症仅少数病例有可复性的白细胞总数下降。

AbstractAlteration of p53 gene and the molecular biologi-cal difference between superficial and invasive bladdercancer were investigated by polymerase chain reaction-single strand conformation polymorphism analysis anddirect sequencing technique. p53 gene mutations wereexamined in exon region 5 to 8 in 21 bladder cancers.Only one of 14 superficial bladder cancers was found tohave p53 gene mutation. Four of 7 invasive bladdercancers with T_2,T_3and T_4were found to have p53 genemutation. p53 gene mutation was...

AbstractAlteration of p53 gene and the molecular biologi-cal difference between superficial and invasive bladdercancer were investigated by polymerase chain reaction-single strand conformation polymorphism analysis anddirect sequencing technique. p53 gene mutations wereexamined in exon region 5 to 8 in 21 bladder cancers.Only one of 14 superficial bladder cancers was found tohave p53 gene mutation. Four of 7 invasive bladdercancers with T_2,T_3and T_4were found to have p53 genemutation. p53 gene mutation was found none of the 4cancers with grade 1, only one of cancers with grade2, four of 12 cancers with grade 3. These results sug-gest that p53 gene play an important role in the devel-opment of human bladder cancer.

作者应用聚合酶链反应-单链构象多态性分析(PCR-SSCP)和直接测序等分子生物学技术,分析检测了21例膀胱移行上皮癌p53基因5~8外显子。结果,在14例浅表性膀胱癌中,发现1例(T_1期)p53基因突变;7例浸润性膀胱癌中,4例发现p53基因突变,其中T_2期1例,T_3期2例,T_4期1例。4例G_1级膀胱癌无一例检出p53突变,5例G_2级膀胱癌1例检出p53突变,12例G_3级肿瘤4例发现p53基因突变。结果表明:p53基因突变在膀胱癌的发生发展中起着重要作用。

 
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